(Drug Name) (Drug Form) (Drug Strength)
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Afinitor DISPERZ: Tablet for oral suspension (2mg)

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What is this Medicine?

EVEROLIMUS (eve ROE li mus) decreases the activity of your immune system. Afinitor is used to treat certain types of cancer.

In-Depth Information

Afinitor DISPERZ 2mg Tablet for Suspension

NDC: 000780626
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Carcinoid, Neuroendocrine Tumor (NET), Astrocytoma

Storage Information
Protect from light
Store in original container
Protect from moisture
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Afinitor DISPERZ 2mg Tablet for Suspension

Reported Side Effects for Afinitor DISPERZ 2mg Tablet for Suspension

Lung Inflammation Incidence:
<4.2%*
Severity: SEVERE
Onset: DELAYED
Decreased Healing Incidence:
<10.0%*
Severity: MODERATE
Onset: DELAYED
Nose Bleed Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hemolytic-uremic Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Moschcowitz Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Angioedema Incidence:
<6.8%*
Severity: SEVERE
Onset: RAPID
Increased Blood Sugar Incidence:
<17.0%*
Severity: SEVERE
Onset: DELAYED
Fluid Retention Incidence:
<3.0%*
Severity: SEVERE
Onset: DELAYED
Fever Incidence:
0.2-6.0%*
Severity: SEVERE
Onset: EARLY
Back Pain Incidence:
0.2-1.0%*
Severity: SEVERE
Onset: DELAYED
Metallic Taste Incidence:
0.2-1.0%*
Severity: SEVERE
Onset: EARLY
Itching Incidence:
0.2-1.0%*
Severity: SEVERE
Onset: RAPID
Headache Incidence:
0.4-1.0%*
Severity: SEVERE
Onset: EARLY
Weight Loss Incidence:
0.5-2.0%*
Severity: SEVERE
Onset: DELAYED
Onycholysis Incidence:
0.5%*
Severity: SEVERE
Onset: DELAYED
Lightheadedness Incidence:
0.5%*
Severity: SEVERE
Onset: EARLY
Migraine Incidence:
0.5%*
Severity: SEVERE
Onset: EARLY
Cough Incidence:
0.6%*
Severity: SEVERE
Onset: DELAYED
Joint Pain Incidence:
0.8-1.5%*
Severity: SEVERE
Onset: DELAYED
Chills Incidence:
1.0-10.0%*
Severity: MILD
Onset: RAPID
Chest Pain Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Blurred Vision Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Drug-Induced Acne Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Conjunctivitis Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Cushingoid Features Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Bruise Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
High Blood Pressure Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: EARLY
Hypoesthesia Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Cyst Of Lymph Fluid Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Muscle And/Or Bone Pain Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Osteopenia Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Paresis Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Paresthesias Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Skin Rash Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Kidney Damage Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: RAPID
Weakness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Wheezing Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: RAPID
Dead Bone Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Low Calcium Levels Incidence:
1.0-37.0%*
Severity: MODERATE
Onset: DELAYED
High Uric Acid Level Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
High Blood Pressure Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Low Blood Sodium Levels Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Low Phosphate Level Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Heart Failure Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Pain Incidence:
1.0-11.0%*
Severity: MILD
Onset: EARLY
Stuffy Nose Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Osteoporosis Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Around The Lungs Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Fluid In Lungs Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: EARLY
Runny Nose Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Gout Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Drowsiness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Hair Loss Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Cataracts Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Fainting Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Wound Dehiscence Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Swelling Incidence:
1.5%*
Severity: SEVERE
Onset: DELAYED
Diabetes Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Low Potassium Levels Incidence:
2.0-4.2%*
Severity: SEVERE
Onset: DELAYED
Weakness Incidence:
2.2-3.0%*
Severity: SEVERE
Onset: DELAYED
Shortness Of Breath Incidence:
2.5-7.0%*
Severity: SEVERE
Onset: EARLY
Bleeding Incidence:
3.0%*
Severity: MODERATE
Onset: EARLY
Dehydration Incidence:
>3.0%*
Severity: SEVERE
Onset: DELAYED
Prolonged Bleeding Time Incidence:
3.0%*
Severity: SEVERE
Onset: DELAYED
Tired Incidence:
3.5-5.0%*
Severity: SEVERE
Onset: EARLY
Feeling Sick Incidence:
3.5%*
Severity: SEVERE
Onset: EARLY
Mouth Ulcers Incidence:
4.0-9.0%*
Severity: SEVERE
Onset: DELAYED
Skin Redness Incidence:
4.0%*
Severity: MODERATE
Onset: EARLY
Mouth Sores Incidence:
4.0-9.0%*
Severity: SEVERE
Onset: DELAYED
Hand And Foot Syndrome Incidence:
5.0%*
Severity: MODERATE
Onset: DELAYED
High Potassium Level Incidence:
7.0-18.0%*
Severity: SEVERE
Onset: DELAYED
Shaking Incidence:
8.0%*
Severity: MILD
Onset: EARLY
Acne Incidence:
10.0-22.0%*
Severity: MILD
Onset: DELAYED
Dry Skin Incidence:
13.0%*
Severity: MILD
Onset: DELAYED
Low Magnesium Levels Incidence:
14.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Afinitor DISPERZ 2mg Tablet for Suspension

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Grapefruit juice and Afinitor DISPERZ 2mg Tablet for Suspension(Everolimus)
Grapefruit juice and Everolimus(Everolimus)
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
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Patient Experiences with Afinitor DISPERZ

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