Amiloride, Hydrochlorothiazide Oral Tablet 5-50Mg Drug Medication Dosage Information
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Amiloride, Hydrochlorothiazide: Oral tablet (5-50mg)

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Drug Image file DrugItem_1206.JPG
Amiloride/HCTZ 5mg-50mg Tab
Mylan Pharmaceuticals Inc
Pill Identification: M 577 
Drug Image file DrugItem_3853.JPG
Amiloride/HCTZ 5mg-50mg Tab
Barr Laboratories Inc a Division of Teva USA
Pill Identification: barr  |  555 483

What is this Medicine?

AMILORIDE; HYDROCHLOROTHIAZIDE (a MIL oh ride; hye droe klor oh THYE a zide) is a combination of two types of diuretics. It helps you make more urine and to lose excess water from your body. This medicine is used to treat high blood pressure and heart failure.

Similar Brand Name Drugs : Moduretic: Oral tablet (5-50mg)
CVS Pharmacy Patient Statistics for Amiloride, Hydrochlorothiazide: Oral tablet(5-50mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Amiloride Hydrochloride/Hydrochlorothiazide 5mg-50mg Tablet

NDC: 003780577
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Edema, Hypertension, Heart Failure

Storage Information
Store at room temperature (between 59 to 86 degrees F)
Protect from light
Amiloride Hydrochloride/Hydrochlorothiazide 5mg-50mg Tablet
Drug Image file DrugItem_1206.JPG
Mylan Pharmaceuticals Inc
Pill Identification: M 577 
Shape: round
Color: peach

Reported Side Effects for Amiloride Hydrochloride/Hydrochlorothiazide 5mg-50mg Tablet

Back Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Vomiting Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Fainting Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Muscle Cramps Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Low White Blood Cell Counts Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Intestinal Bleeding Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
No White Blood Cells Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Balance Problems Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Lyell'S Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Paresthesias Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Pancytopenia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Feeling Sick Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Hiccups Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Flushing Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Diaphoresis Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Confusion Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Hemolytic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hair Loss Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Gas Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Exfoliative Dermatitis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Erythema Multiforme Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Drowsiness Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Constipation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Aplastic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Low Platelet Count Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Stevens-Johnson Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Postural Low Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cells Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Inability To Sleep Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Painful Urination Incidence:
>1.0%*
Severity: MODERATE
Onset: EARLY
Shortness Of Breath Incidence:
>1.0%*
Severity: MODERATE
Onset: EARLY
Nighttime Urination Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Itching Incidence:
1.0-3.0%*
Severity: MILD
Onset: RAPID
Loose Stools Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Impotence (erectile Dysfunction) Incidence:
>1.0%*
Severity: MODERATE
Onset: DELAYED
Uncontrolled Urination Incidence:
>1.0%*
Severity: MODERATE
Onset: EARLY
Kidney Failure Incidence:
>1.0%*
Severity: SEVERE
Onset: DELAYED
High Potassium Level Incidence:
1.0-2.0%*
Severity: SEVERE
Onset: DELAYED
Upset Stomach Incidence:
3.0-8.0%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
3.0-8.0%*
Severity: MILD
Onset: EARLY
Decreased Appetite Incidence:
3.0-8.0%*
Severity: MILD
Onset: DELAYED
Skin Rash Incidence:
3.0-8.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
3.0-8.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
3.0-8.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Amiloride Hydrochloride/Hydrochlorothiazide 5mg-50mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Alcohol and Amiloride Hydrochloride/Hydrochlorothiazide 5mg-50mg Tablet(Amiloride Hydrochloride)
Alcohol and Antihypertensives(Amiloride Hydrochloride)
Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Pregnancy & Lactation Information
FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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