Arthrotec Oral Tablet, Gastro-Resistant 50-200Mcg Drug Medication Dosage Information
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Arthrotec: Oral tablet, gastro-resistant (50-200mcg)

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Drug Image file DrugItem_745.JPG
Arthrotec 50 DR Tab
Pfizer US Pharmaceuticals
Pill Identification: SEARLE 1411  |  A A A A 50

What is this Medicine?

DICLOFENAC; MISOPROSTOL (dye KLOE fen ak; mye soe PROST ole) is a combination of two different drugs. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It is used to reduce swelling and to treat pain. Misoprostol protects the stomach against ulcers. This medicine is used for arthritis in people who are at high risk for stomach ulcers from NSAID treatment.

CVS Pharmacy Patient Statistics for Arthrotec: Oral tablet, gastro-resistant(50-200mcg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Arthrotec 50 Delayed-Release Tablet

NDC: 000251411
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Rheumatoid Arthritis, Osteoarthritis

Storage Information
Store in a dry place
Store below 77 degrees F
Arthrotec 50 Delayed-Release Tablet
Drug Image file DrugItem_745.JPG
Pfizer US Pharmaceuticals
Pill Identification: SEARLE 1411  |  A A A A 50
Shape: round
Color: white

Reported Side Effects for Arthrotec 50 Delayed-Release Tablet

Elevated Hepatic Enzymes Incidence:
1.0-15.0%*
Severity: MODERATE
Onset: DELAYED
Stomach Ulcer Incidence:
3.0-11.0%*
Severity: SEVERE
Onset: DELAYED
Gas Incidence:
9.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
11.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
14.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
19.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
21.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Arthrotec 50 Delayed-Release Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Arthrotec 50 Delayed-Release Tablet(Diclofenac Sodium)
Alcohol and Nonsteroidal antiinflammatory drugs (systemic)(Diclofenac Sodium)
Side effects from this drug may get worse if you drink alcohol-containing drinks. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. It is best to limit or avoid alcohol containing drinks while taking this drug, even with short term use. Many non-prescription products for headaches, pain, arthritis, or sinus pain contain drugs that may cause stomach problems along with alcohol; closely read labels before taking any medicines with alcohol-containing drinks.
Moderate Lifestyle Interaction
Tobacco and Arthrotec 50 Delayed-Release Tablet(Diclofenac Sodium)
Tobacco and Nonsteroidal antiinflammatory drugs (systemic)(Diclofenac Sodium)
Side effects from Nonsteroidal anti-inflammatory drugs may get worse if you use tobacco-containing products such as cigarettes. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. Many non-prescription products contain NSAIDs; closely read labels before taking any medicines. Eye or Skin products containing NSAIDs should not interact with tobacco.
Moderate Lifestyle Interaction
Marijuana and Arthrotec 50 Delayed-Release Tablet(Diclofenac Sodium)
Marijuana and Nonsteroidal antiinflammatory drugs (systemic)(Diclofenac Sodium)
Although an interaction is possible, these drugs may be used together. In therory, the actions of Marijuana, Medical may be decreased if you take Nonsteroidal Antiinflammatory Drugs (NSAIDs). However, the importance of this interaction is not known. Patients receiving this drug combination may notice decreased euphoria and heart rate.
Pregnancy & Lactation Information
FIRST Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

SECOND Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

THIRD Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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