Avastin Solution For Injection 25Mg Drug Medication Dosage Information
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Avastin: Solution for injection (25mg)

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What is this Medicine?

BEVACIZUMAB (be va SIZ yoo mab) is a chemotherapy drug. It targets a protein found in many cancer cell types, and halts cancer growth. This drug treats many cancers including non-small cell lung cancer, ovarian cancer, cervical cancer, and colon or rectal cancer. It is usually given with other chemotherapy drugs.

In-Depth Information
Select a Medication

Avastin 100mg/4ml Solution for Injection

NDC: 502420060
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Colorectal Cancer, Cervical Cancer, Non-small Cell Lung Cancer (NSCLC), Renal Cell Cancer, Glioblastoma Multiforme

Sometimes used for but not FDA approved for the following conditions:
Breast Cancer, Macular Degeneration, Ovarian Cancer, Diabetic Retinopathy, Diabetic Macular Edema

Storage Information
Store reconstituted product in refrigerator (36 to 46 degrees F), discard if not used within 8 hours
Refrigerate (between 36 and 46 degrees F)
Protect from light
Discard product if it contains particulate matter, is cloudy, or discolored
Store in carton until time of use
Discard unused portion. Do not store for later use.
Do not freeze
Avastin 100mg/4ml Solution for Injection

Reported Side Effects for Avastin 100mg/4ml Solution for Injection

Low Magnesium Levels Incidence:
<24.0%*
Severity: MODERATE
Onset: DELAYED
Low Blood Sodium Levels Incidence:
<3.7%*
Severity: SEVERE
Onset: DELAYED
Nephrotic Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Dysarthria Incidence:
<8.0%*
Severity: MODERATE
Onset: DELAYED
Back Pain Incidence:
<5.5%*
Severity: SEVERE
Onset: DELAYED
Increased Blood Sugar Incidence:
<26.0%*
Severity: MODERATE
Onset: DELAYED
Low Albumin In Blood Incidence:
<16.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
<15.0%*
Severity: MODERATE
Onset: DELAYED
Nervousness Incidence:
<17.0%*
Severity: MILD
Onset: DELAYED
Kidney Failure Incidence:
<16.0%*
Severity: SEVERE
Onset: DELAYED
Dehydration Incidence:
<4.1%*
Severity: SEVERE
Onset: DELAYED
Heart Failure Incidence:
<2.2%*
Severity: SEVERE
Onset: DELAYED
Brain Deterioration Incidence:
<0.5%*
Severity: SEVERE
Onset: DELAYED
Low Lymphocytes Incidence:
<6.0%*
Severity: SEVERE
Onset: DELAYED
Hand And Foot Syndrome Incidence:
<4.5%*
Severity: SEVERE
Onset: DELAYED
Pelvic Pain Incidence:
<5.5%*
Severity: SEVERE
Onset: DELAYED
Bleeding Incidence:
0.4-6.9%*
Severity: SEVERE
Onset: EARLY
Antibody Formation Incidence:
0.6%*
Severity: MODERATE
Onset: DELAYED
Protein In The Urine Incidence:
0.7-7.4%*
Severity: SEVERE
Onset: DELAYED
Inflamed Colon Incidence:
1.0-6.0%*
Severity: MODERATE
Onset: DELAYED
Wound Dehiscence Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Loose Stools Incidence:
1.0-34.0%*
Severity: MILD
Onset: EARLY
High Bilirubin Level Incidence:
1.0-7.0%*
Severity: MODERATE
Onset: DELAYED
Bleeding In The Brain Incidence:
1.2-4.9%*
Severity: SEVERE
Onset: DELAYED
Acne Incidence:
1.5%*
Severity: MILD
Onset: DELAYED
Blood Clot In Lung Incidence:
1.5%*
Severity: SEVERE
Onset: DELAYED
Inflamed Stomach Incidence:
1.5%*
Severity: MODERATE
Onset: DELAYED
Mouth Sores Incidence:
1.8%*
Severity: MODERATE
Onset: DELAYED
Blood Clot Incidence:
2.0-31.5%*
Severity: SEVERE
Onset: DELAYED
Blood Clot Incidence:
2.0-31.5%*
Severity: SEVERE
Onset: DELAYED
Skin Discoloration Incidence:
2.0-16.0%*
Severity: MILD
Onset: DELAYED
Ringing In Ears Incidence:
2.1%*
Severity: MILD
Onset: DELAYED
Gum Inflammation Incidence:
2.4%*
Severity: MILD
Onset: DELAYED
Heartburn Incidence:
2.4%*
Severity: MILD
Onset: DELAYED
Blurred Vision Incidence:
2.4%*
Severity: MODERATE
Onset: EARLY
Headache Incidence:
3.0-4.0%*
Severity: SEVERE
Onset: EARLY
Increased Urination Incidence:
3.0-6.0%*
Severity: MILD
Onset: EARLY
Urinary Urgency Incidence:
3.0-6.0%*
Severity: MILD
Onset: EARLY
Skin Rash Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Decreased Healing Incidence:
3.0-6.0%*
Severity: MODERATE
Onset: DELAYED
Fainting Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Infection Incidence:
3.2-10.0%*
Severity: SEVERE
Onset: DELAYED
Bowel Obstruction Incidence:
4.0%*
Severity: SEVERE
Onset: DELAYED
Tired Incidence:
4.0-80.0%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
4.0%*
Severity: SEVERE
Onset: DELAYED
Bone Pain Incidence:
4.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
4.0-12.0%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
4.0-7.0%*
Severity: MILD
Onset: EARLY
Vaginal Bleeding Incidence:
4.0%*
Severity: MODERATE
Onset: DELAYED
High Blood Pressure Incidence:
5.0-18.0%*
Severity: SEVERE
Onset: EARLY
Lung Inflammation Incidence:
5.0%*
Severity: MODERATE
Onset: DELAYED
Low Platelet Count Incidence:
5.0%*
Severity: MODERATE
Onset: DELAYED
Nose Bleed Incidence:
5.0-35.0%*
Severity: MILD
Onset: DELAYED
Skin Ulcer Incidence:
6.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
6.0-52.0%*
Severity: MILD
Onset: EARLY
Hair Loss Incidence:
6.0-32.0%*
Severity: MILD
Onset: DELAYED
Low Blood Pressure Incidence:
7.0-15.0%*
Severity: MODERATE
Onset: RAPID
Dry Skin Incidence:
7.0-20.0%*
Severity: MILD
Onset: DELAYED
Low Potassium Levels Incidence:
7.3%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cells Incidence:
7.8-26.2%*
Severity: SEVERE
Onset: DELAYED
Stomach Pain Incidence:
8.0%*
Severity: SEVERE
Onset: EARLY
Weight Loss Incidence:
9.0-21.0%*
Severity: MILD
Onset: DELAYED
Rhinitis Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
10.0%*
Severity: SEVERE
Onset: DELAYED
Mouth Ulcers Incidence:
12.8-32.0%*
Severity: MODERATE
Onset: DELAYED
Metallic Taste Incidence:
14.0-21.0%*
Severity: MILD
Onset: EARLY
Muscle Pain Incidence:
14.0-19.0%*
Severity: MILD
Onset: EARLY
Nerve Pain Incidence:
17.0-24.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
17.0-24.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
19.0-26.0%*
Severity: MILD
Onset: EARLY
Intestinal Bleeding Incidence:
24.0%*
Severity: SEVERE
Onset: DELAYED
Shortness Of Breath Incidence:
25.0-27.0%*
Severity: MODERATE
Onset: EARLY
Decreased Appetite Incidence:
34.0-43.0%*
Severity: MILD
Onset: DELAYED
No Menstrual Periods Incidence:
34.0%*
Severity: MILD
Onset: DELAYED
Low White Blood Cell Counts Incidence:
37.0%*
Severity: MODERATE
Onset: DELAYED
Exfoliative Dermatitis Incidence:
84.0%*
Severity: SEVERE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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