Bosulif Oral Tablet 100Mg Drug Medication Dosage Information
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BOSULIF: Oral tablet (100mg)

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What is this Medicine?

BOSUTINIB (boe SUE ti nib) is medicine that targets proteins in cancer cells and stops the cancer cell from growing. It is used to treat chronic myelogenous leukemia.

In-Depth Information

Bosulif 100mg Tablet

NDC: 000690135
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Chronic Myelogenous Leukemia (CML)

Storage Information
Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees F
Bosulif 100mg Tablet

Reported Side Effects for Bosulif 100mg Tablet

Joint Pain Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Lightheadedness Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Swelling Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Fluid Retention Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Infection Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Severe Allergy Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: RAPID
Fluid In Lungs Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Inflamed Heart Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
High Pressure In Lungs Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Erythema Multiforme Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Pancreas Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Intestinal Bleeding Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Long Qt Syndrome Incidence:
0.2-10.0%*
Severity: MODERATE
Onset: RAPID
Itching Incidence:
1.0%*
Severity: SEVERE
Onset: RAPID
Ringing In Ears Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Hives Incidence:
1.0-10.0%*
Severity: MILD
Onset: RAPID
Liver Infection Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Flu Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Weakness Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Back Pain Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Chest Pain Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Metallic Taste Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Kidney Failure Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Upset Stomach Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Acne Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Decreased Appetite Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Dehydration Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Fever Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Inflamed Stomach Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
High Bilirubin Level Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
High Potassium Level Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Fluid Around The Lungs Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Pain Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Fluid Around The Heart Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Stomach Pain Incidence:
2.0%*
Severity: SEVERE
Onset: EARLY
Headache Incidence:
2.0%*
Severity: SEVERE
Onset: EARLY
Feeling Sick Incidence:
2.0%*
Severity: SEVERE
Onset: EARLY
Tired Incidence:
2.0%*
Severity: SEVERE
Onset: EARLY
Shortness Of Breath Incidence:
2.0%*
Severity: SEVERE
Onset: EARLY
Vomiting Incidence:
3.0%*
Severity: SEVERE
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
3.0-7.0%*
Severity: SEVERE
Onset: DELAYED
Skin Rash Incidence:
7.0%*
Severity: SEVERE
Onset: EARLY
Low Phosphate Level Incidence:
7.0%*
Severity: SEVERE
Onset: DELAYED
Loose Stools Incidence:
8.0%*
Severity: SEVERE
Onset: EARLY
Sore Throat Incidence:
10.0%*
Severity: MILD
Onset: DELAYED
Low White Blood Cells Incidence:
12.0%*
Severity: SEVERE
Onset: DELAYED
Anemia Incidence:
14.0%*
Severity: MODERATE
Onset: DELAYED
Cough Incidence:
20.0%*
Severity: MILD
Onset: DELAYED
Low Platelet Count Incidence:
29.0%*
Severity: SEVERE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Bosulif 100mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Grapefruit juice and Bosulif 100mg Tablet(Bosutinib)
Grapefruit juice and Bosutinib(Bosutinib)
If you drink grapefruit juice, talk to your health care professional. Taking bosutinib and grapefruit juice together may result in increased levels of bosutinib in your body and increased risk for bosutinib side effects such as diarrhea, nausea/vomiting, low blood counts, and/or liver problems.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
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