Busulfex Solution For Injection 6Mg Drug Medication Dosage Information
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Busulfex: Solution for injection (6mg)

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What is this Medicine?

BUSULFAN (byoo SUL fan) is a chemotherapy drug. It is used prior to a stem cell transplant in patients with chronic myelogenous leukemia.

In-Depth Information
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Busulfex 6mg/ml Solution for Injection

NDC: 591480070
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Stem Cell Transplant Preparation

Storage Information
Refrigerate (between 36 and 46 degrees F)
Busulfex 6mg/ml Solution for Injection

Reported Side Effects for Busulfex 6mg/ml Solution for Injection

Pancytopenia Incidence:
<100.0%*
Severity: SEVERE
Onset: DELAYED
Fever Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Rash With Pustules Incidence:
<8.0%*
Severity: MILD
Onset: EARLY
High Bilirubin Level Incidence:
<30.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cells Incidence:
<100.0%*
Severity: MODERATE
Onset: DELAYED
Pulmonary Fibrosis Incidence:
<16.9%*
Severity: SEVERE
Onset: DELAYED
Mouth Ulcers Incidence:
<26.0%*
Severity: SEVERE
Onset: DELAYED
Low Platelet Count Incidence:
<100.0%*
Severity: MODERATE
Onset: DELAYED
Dry Mouth Incidence:
<26.0%*
Severity: MILD
Onset: EARLY
Blistery Rash Incidence:
<10.0%*
Severity: MODERATE
Onset: EARLY
Infection Incidence:
<51.0%*
Severity: MILD
Onset: DELAYED
Yellow Skin Incidence:
<12.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
<100.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
<7.0%*
Severity: SEVERE
Onset: EARLY
Hair Loss Incidence:
<17.0%*
Severity: MILD
Onset: DELAYED
Anemia Incidence:
<69.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Appetite Incidence:
<21.0%*
Severity: SEVERE
Onset: DELAYED
Aplastic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Vesicular Rash Incidence:
<10.0%*
Severity: MILD
Onset: DELAYED
Constipation Incidence:
<38.0%*
Severity: MODERATE
Onset: DELAYED
Cough Incidence:
<28.0%*
Severity: MILD
Onset: DELAYED
Skin Rash Incidence:
<57.0%*
Severity: MILD
Onset: EARLY
Shortness Of Breath Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Skin Discoloration Incidence:
<8.0%*
Severity: MILD
Onset: DELAYED
Loose Stools Incidence:
<5.0%*
Severity: SEVERE
Onset: EARLY
Inability To Sleep Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Bleeding In The Brain Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Coma Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Prolonged Bleeding Time Incidence:
2.0%*
Severity: MODERATE
Onset: DELAYED
Distressed Incidence:
2.0%*
Severity: MILD
Onset: EARLY
Convulsions Incidence:
2.0-6.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Pancreas Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Weakness Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Throat Inflammation Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Overbreathing Incidence:
2.0%*
Severity: SEVERE
Onset: EARLY
Heart Failure Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Brain Dysfunction Incidence:
2.0%*
Severity: MODERATE
Onset: DELAYED
Drowsiness Incidence:
2.0%*
Severity: MILD
Onset: EARLY
Irregular Heart Beat Incidence:
2.0%*
Severity: SEVERE
Onset: EARLY
Low Blood Sodium Levels Incidence:
2.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Of Blood Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Delirium Incidence:
2.0%*
Severity: MODERATE
Onset: EARLY
Rash Of Red Skin Bumps Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Fluid Around The Heart Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Hypoxia Incidence:
2.0%*
Severity: MODERATE
Onset: EARLY
Coughing Up Blood Incidence:
3.0%*
Severity: MODERATE
Onset: DELAYED
Low Blood Pressure Incidence:
3.0%*
Severity: SEVERE
Onset: RAPID
Low Calcium Levels Incidence:
3.0%*
Severity: SEVERE
Onset: DELAYED
Fluid Around The Lungs Incidence:
3.0%*
Severity: SEVERE
Onset: DELAYED
Stomach Pain Incidence:
3.0%*
Severity: SEVERE
Onset: EARLY
Sinus Infection Incidence:
3.0%*
Severity: MILD
Onset: DELAYED
Headache Incidence:
5.0%*
Severity: SEVERE
Onset: EARLY
Hallucinations Incidence:
5.0%*
Severity: MODERATE
Onset: EARLY
Enlarged Liver Incidence:
6.0%*
Severity: MODERATE
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
7.0%*
Severity: SEVERE
Onset: DELAYED
Tiredness Incidence:
7.0%*
Severity: MILD
Onset: EARLY
Acne Incidence:
7.0%*
Severity: MILD
Onset: DELAYED
Painful Urination Incidence:
7.0%*
Severity: MODERATE
Onset: EARLY
Painful Bloody Urine Incidence:
7.0-24.0%*
Severity: SEVERE
Onset: DELAYED
High Blood Pressure Incidence:
7.0%*
Severity: SEVERE
Onset: EARLY
Sinusoidal Obstruction Syndrome (SOS) Incidence:
7.7-12.0%*
Severity: SEVERE
Onset: DELAYED
Veno-occlusive Disease (VOD) Incidence:
7.7-12.0%*
Severity: SEVERE
Onset: DELAYED
Weight Gain Incidence:
8.0%*
Severity: MILD
Onset: DELAYED
Blood In The Urine Incidence:
8.0%*
Severity: MODERATE
Onset: DELAYED
Bowel Obstruction Incidence:
8.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Confusion Incidence:
11.0%*
Severity: MODERATE
Onset: EARLY
Joint Pain Incidence:
13.0%*
Severity: MILD
Onset: DELAYED
Decreased Urination Incidence:
15.0%*
Severity: SEVERE
Onset: EARLY
Increased Blood Sugar Incidence:
15.0%*
Severity: SEVERE
Onset: DELAYED
Injection Site Reaction Incidence:
15.0-25.0%*
Severity: MILD
Onset: RAPID
Muscle Pain Incidence:
16.0%*
Severity: MILD
Onset: EARLY
Low Phosphate Level Incidence:
17.0%*
Severity: MODERATE
Onset: DELAYED
Sore Throat Incidence:
18.0%*
Severity: MILD
Onset: DELAYED
Hiccups Incidence:
18.0%*
Severity: MILD
Onset: EARLY
Back Pain Incidence:
23.0%*
Severity: MILD
Onset: DELAYED
Depression Incidence:
23.0%*
Severity: MODERATE
Onset: DELAYED
Nose Bleed Incidence:
25.0%*
Severity: MILD
Onset: DELAYED
Hot Flashes Incidence:
25.0%*
Severity: MODERATE
Onset: EARLY
Flushing Incidence:
25.0%*
Severity: MILD
Onset: RAPID
Chest Pain Incidence:
26.0%*
Severity: MODERATE
Onset: EARLY
Itching Incidence:
28.0%*
Severity: MILD
Onset: RAPID
Lightheadedness Incidence:
30.0%*
Severity: MILD
Onset: EARLY
Blood Clot Incidence:
33.0%*
Severity: SEVERE
Onset: DELAYED
Rhinitis Incidence:
44.0%*
Severity: MILD
Onset: EARLY
Rapid Heart Rate Incidence:
44.0%*
Severity: MODERATE
Onset: RAPID
Upset Stomach Incidence:
44.0%*
Severity: MILD
Onset: EARLY
Chills Incidence:
46.0%*
Severity: MILD
Onset: RAPID
Low Potassium Levels Incidence:
>62.0%*
Severity: MODERATE
Onset: DELAYED
Nervousness Incidence:
72.0%*
Severity: MILD
Onset: DELAYED
Low Magnesium Levels Incidence:
77.0%*
Severity: MODERATE
Onset: DELAYED
Low Lymphocytes Incidence:
79.0%*
Severity: MODERATE
Onset: DELAYED
Swelling Incidence:
79.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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