Cardene Iv Solution For Injection 0.1Mg Drug Medication Dosage Information
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Cardene IV: Solution for injection (0.1mg)

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What is this Medicine?

NICARDIPINE (nye KAR de peen) is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used for the short-term treatment of high blood pressure when the patient is not able to take oral therapy.

In-Depth Information
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Cardene I.V. 20mg/200ml in Dextrose 4.8% Premixed Solution for Injection

NDC: 244770312
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Hypertension

Sometimes used for but not FDA approved for the following conditions:
Hypertensive Emergency, Hypertensive Urgency, Postoperative Hypertension

Storage Information
Protect from light
Store in carton until time of use
Store at controlled room temperature (between 68 and 77 degrees F)
Protect from freezing
Avoid excessive heat (above 104 degrees F)
Cardene I.V. 20mg/200ml in Dextrose 4.8% Premixed Solution for Injection

Reported Side Effects for Cardene I.V. 20mg/200ml in Dextrose 4.8% Premixed Solution for Injection

Rapid Heart Rate Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Heart Attack Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Confusion Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Heart Block Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Depression Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Irregular Heart Beat Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Nervousness Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Inflamed Heart Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Vomiting Incidence:
0.4-7.0%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
0.4-1.4%*
Severity: MILD
Onset: EARLY
Shaking Incidence:
0.6%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
0.6%*
Severity: MODERATE
Onset: DELAYED
Feeling Sick Incidence:
0.6%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
0.6%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
0.8-1.5%*
Severity: MILD
Onset: EARLY
Fainting Incidence:
0.8%*
Severity: MILD
Onset: EARLY
Rapid Heart Rate Incidence:
0.8-5.0%*
Severity: MODERATE
Onset: RAPID
Weakness Incidence:
0.9-5.2%*
Severity: MILD
Onset: DELAYED
Low Blood Pressure Incidence:
0.9-8.0%*
Severity: MODERATE
Onset: RAPID
Chest Pain Incidence:
1.0-7.0%*
Severity: MODERATE
Onset: EARLY
Paresthesias Incidence:
1.0%*
Severity: MILD
Onset: DELAYED
Swelling Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Postural Low Blood Pressure Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Drowsiness Incidence:
1.1-1.4%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
1.6-6.9%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
1.9-7.0%*
Severity: MILD
Onset: EARLY
Rapid Heart Rate Incidence:
2.8-4.1%*
Severity: MODERATE
Onset: EARLY
Fluid Retention Incidence:
5.9-8.0%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
6.2-21.0%*
Severity: MILD
Onset: EARLY
Flushing Incidence:
9.7%*
Severity: MILD
Onset: RAPID
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Cardene I.V. 20mg/200ml in Dextrose 4.8% Premixed Solution for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Grapefruit juice and Cardene I.V. 20mg/200ml in Dextrose 4.8% Premixed Solution for Injection(Nicardipine Hydrochloride)
Grapefruit juice and Nicardipine Hydrochloride(Nicardipine Hydrochloride)
Avoid taking Nicardipine with grapefruit juice. Grapefruit juice and grapefruit-containing foods may increase the effects of Nicardipine. If the blood pressure drops too low while taking this medicine, you may become dizzy or feel faint; do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away while taking this medicine. If you notice new or increased swelling of your legs or ankles, tell your health care provider.
Moderate Lifestyle Interaction
Marijuana and Cardene I.V. 20mg/200ml in Dextrose 4.8% Premixed Solution for Injection(Nicardipine Hydrochloride)
Marijuana and Nicardipine Hydrochloride(Nicardipine Hydrochloride)
Nicardipine can theoretically decrease the elimination of Marijuana, Medical from the body. Side effects from Marijuana, Medical may worsen if you take Nicardipine. You may feel drowsy or more tired. Do not drive or operate machinery until you know how these drugs affect you. Contact your health care provider immediately if you notice slurred speech, confusion, increases heart rate, or palpitations while taking Marijuana, Medical.
Moderate Lifestyle Interaction
Alcohol and Cardene I.V. 20mg/200ml in Dextrose 4.8% Premixed Solution for Injection(Nicardipine Hydrochloride)
Alcohol and Antihypertensives(Nicardipine Hydrochloride)
Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Compatible - This drug is generally safe to take by nursing mothers.


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