Cenestin Oral Tablet 0.45Mg Drug Medication Dosage Information
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Cenestin: Oral tablet (0.45mg)

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Drug Image file DrugItem_3478.JPG
Cenestin 0.45mg Tab
Teva Women's Health, Inc.
Pill Identification: 46  |  dp

What is this Medicine?

SYNTHETIC CONJUGATED ESTROGENS (A) (sin THET ic CON ju gate ed ESS troe jenz A) is an estrogen. It is mostly used as hormone replacement in menopausal women to treat hot flashes.

CVS Pharmacy Patient Statistics for Cenestin: Oral tablet(0.45mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information

Cenestin 0.45mg Tablet

NDC: 512850446
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Menopause, Dyspareunia, Hot Flashes, Atrophic Vaginitis

Sometimes used for but not FDA approved for the following conditions:
Oophorectomy, Hypogonadism, Osteoporosis Prophylaxis, Prostate Cancer, Palliative Treatment Of Breast Cancer

Storage Information
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Cenestin 0.45mg Tablet
Drug Image file DrugItem_3478.JPG
Teva Women's Health, Inc.
Pill Identification: 46  |  dp
Shape: round
Color: orange

Reported Side Effects for Cenestin 0.45mg Tablet

Elevated Hepatic Enzymes Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Abnormal Cervical Cells Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Increase In Breast Size Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Fluid From Breast Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Drug-Induced Acne Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Vomiting Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Yellow Skin Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Increased Blood Sugar Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Weight Gain Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Blood Clot In Eye Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Skin Rash Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Paresthesias Incidence:
<6.0%*
Severity: MILD
Onset: DELAYED
Heavy Menstrual Period Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Increased Sexual Desire Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Decreased Sexual Desire Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Irritability Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Galactorrhea Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Rash Of Red Skin Bumps Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Emotional Lability Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Erythema Multiforme Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hirsutism Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
High Blood Pressure Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
High Triglycerides Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Swelling Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
<7.0%*
Severity: MILD
Onset: EARLY
Breast Pain Incidence:
<14.0%*
Severity: MILD
Onset: DELAYED
Melasma Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Gallstones Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Cholecystitis Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Itching Incidence:
<5.0%*
Severity: MILD
Onset: RAPID
Hives Incidence:
<5.0%*
Severity: MILD
Onset: RAPID
Hair Loss Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Stomach Pain Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Blockage Of Bile Duct Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Cholestasis Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Acne Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Menstrual Cramps Incidence:
1.0-8.0%*
Severity: MILD
Onset: DELAYED
Endometrial Hyperplasia Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Lightheadedness Incidence:
1.0-7.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
1.4-8.0%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
1.4-8.0%*
Severity: MILD
Onset: DELAYED
Breakthrough Bleeding Incidence:
2.0-14.0%*
Severity: MILD
Onset: DELAYED
Nervousness Incidence:
2.0-5.0%*
Severity: MILD
Onset: DELAYED
Inability To Sleep Incidence:
2.9-7.0%*
Severity: MILD
Onset: EARLY
Muscle Cramps Incidence:
3.0-7.0%*
Severity: MILD
Onset: DELAYED
Vaginal Discharge Incidence:
3.0-7.0%*
Severity: MILD
Onset: DELAYED
Vaginal Discharge Incidence:
3.0-7.0%*
Severity: MILD
Onset: DELAYED
Peripheral Vasodilation Incidence:
3.0-5.0%*
Severity: MODERATE
Onset: RAPID
Joint Pain Incidence:
3.5-14.0%*
Severity: MILD
Onset: DELAYED
Gas Incidence:
4.0-7.0%*
Severity: MILD
Onset: EARLY
Vaginal Infection Incidence:
4.2-7.0%*
Severity: MODERATE
Onset: DELAYED
Yeast Infection Incidence:
5.0-6.0%*
Severity: MODERATE
Onset: DELAYED
Muscle Pain Incidence:
5.0-9.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
5.0-7.0%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
6.0-12.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
9.0-11.0%*
Severity: MILD
Onset: EARLY
No Menstrual Periods Incidence:
>10.0%*
Severity: MILD
Onset: DELAYED
Back Pain Incidence:
13.0-14.0%*
Severity: MILD
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Cenestin 0.45mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Minor Lifestyle Interaction
Grapefruit juice and Cenestin 0.45mg Tablet(Synthetic Conjugated Estrogens (A))
Grapefruit juice and Estrogens(Synthetic Conjugated Estrogens (A))
Grapefruit juice and grapefruit-containing foods may increase the side effects of estrogen in some females, such as nausea, breast tenderness, headache or fluid retention. There may be no interaction. Do not significantly change your grapefruit intake while taking estrogens for hormone replacement therapy or as part of hormonal birth control products. Report any unusual side effects, like unusual non-menstrual vaginal bleeding, promptly for evaluation.
Pregnancy & Lactation Information
FIRST Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

SECOND Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

THIRD Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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