Cimetidine, Sodium Chloride Solution For Injection 300-0.9pct Drug Medication Dosage Information
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Cimetidine, Sodium Chloride: Solution for injection (300-0.9%)

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What is this Medicine?

CIMETIDINE (sye MET i deen) is a type of antihistamine that blocks the release of stomach acid. It is used to treat stomach or intestinal ulcers. It can relieve ulcer pain and discomfort, and the heartburn from acid reflux.

In-Depth Information
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Cimetidine Hydrochloride 300mg/50ml in Sodium Chloride 0.9% Solution for Injection

NDC: 000747447
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Multiple Endocrine Adenoma Syndrome, Upper GI Bleeding, Systemic Mastocytosis, Gastric Ulcer, Zollinger-Ellison Syndrome, Gastritis, Duodenal Ulcer, Stress Gastritis Prophylaxis

Sometimes used for but not FDA approved for the following conditions:
Angioedema, Aspiration Prophylaxis, Urticaria

Cimetidine Hydrochloride 300mg/50ml in Sodium Chloride 0.9% Solution for Injection

Reported Side Effects for Cimetidine Hydrochloride 300mg/50ml in Sodium Chloride 0.9% Solution for Injection

Retaining Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
No White Blood Cells Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Cholestasis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Infection Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Low White Blood Cell Counts Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Blood Vessels Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Kidney Inflammation Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Lyell'S Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hair Loss Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Joint Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Heart Block Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Slow Heart Beat Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Erythema Multiforme Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Exfoliative Dermatitis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Fever Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Low Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Muscle Pain Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Low White Blood Cells Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Stevens-Johnson Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Low Platelet Count Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Gynecomastia Incidence:
0.3-4.0%*
Severity: MILD
Onset: DELAYED
Lightheadedness Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
2.1-3.5%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Cimetidine Hydrochloride 300mg/50ml in Sodium Chloride 0.9% Solution for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Marijuana and Cimetidine Hydrochloride 300mg/50ml in Sodium Chloride 0.9% Solution for Injection(Cimetidine Hydrochloride)
Marijuana and Cimetidine(Cimetidine Hydrochloride)
Cimetidine can theoretically decrease the elimination of Marijuana, Medical from the body. Side effects from Marijuana, Medical may worsen if you take Cimetidine. You may feel drowsy or more tired. Do not drive or operate machinery until you know how these drugs affect you. Contact your health care provider immediately if you notice slurred speech, confusion, increases heart rate, or palpitations while taking Marijuana, Medical.
Minor Lifestyle Interaction
Caffeine-containing Foods/Beverages and Cimetidine Hydrochloride 300mg/50ml in Sodium Chloride 0.9% Solution for Injection(Cimetidine Hydrochloride)
Caffeine-containing Foods/Beverages and Cimetidine(Cimetidine Hydrochloride)
Although an interaction is possible, these drugs are often used together. Side effects from Caffeine may get worse if you take Cimetidine. Too much Caffeine can cause effects like nausea, nervousness, or sleeplessness. You may need to limit your Caffeine intake. Common foods and beverages containing caffeine include coffee, teas, colas and chocolate. Many non-prescription drugs and diet aids may also contain caffeine.
Minor Lifestyle Interaction
Alcohol and Cimetidine Hydrochloride 300mg/50ml in Sodium Chloride 0.9% Solution for Injection(Cimetidine Hydrochloride)
Alcohol and H2-blockers(Cimetidine Hydrochloride)
Side effects from drinking alcohol-containing drinks may get worse if you take H2-blockers such as cimetidine, famotidine, nizatidine, and ranitidine. Avoid or minimize your intake of alcohol-containing drinks while taking H2-blockers.
Pregnancy & Lactation Information
FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Compatible - This drug is generally safe to take by nursing mothers.


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