Clolar Solution For Injection 1Mg Drug Medication Dosage Information
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Clolar: Solution for injection (1mg)

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What is this Medicine?

CLOFARABINE (kloe FAR a been) is a chemotherapy drug. It reduces the growth of cancer cells and can suppress the immune system. It is used for treating leukemia.

In-Depth Information
Select a Medication

Clolar 1mg/ml Solution for Injection

NDC: 584680100
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Acute Lymphocytic Leukemia (ALL)

Storage Information
Store diluted product at room temperature (59 to 86 degrees F) for up to 24 hours
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Clolar 1mg/ml Solution for Injection

Reported Side Effects for Clolar 1mg/ml Solution for Injection

Intestinal Bleeding Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Skin Rash Incidence:
<7.0%*
Severity: SEVERE
Onset: EARLY
Infection Incidence:
0.9-11.3%*
Severity: SEVERE
Onset: DELAYED
Irritability Incidence:
0.9%*
Severity: SEVERE
Onset: DELAYED
Stomach Pain Incidence:
0.9-12.2%*
Severity: SEVERE
Onset: EARLY
Mouth Ulcers Incidence:
0.9%*
Severity: SEVERE
Onset: DELAYED
Tiredness Incidence:
0.9%*
Severity: SEVERE
Onset: EARLY
Itching Incidence:
0.9%*
Severity: SEVERE
Onset: RAPID
Distressed Incidence:
0.9%*
Severity: SEVERE
Onset: EARLY
Drowsiness Incidence:
0.9%*
Severity: SEVERE
Onset: EARLY
Yeast Infection Incidence:
0.9-1.7%*
Severity: SEVERE
Onset: DELAYED
Inflamed Pancreas Incidence:
1.0-4.0%*
Severity: SEVERE
Onset: DELAYED
Flu Incidence:
1.0-4.0%*
Severity: MILD
Onset: DELAYED
Fluid In Lungs Incidence:
1.0-4.0%*
Severity: SEVERE
Onset: EARLY
Sinus Infection Incidence:
1.0-4.0%*
Severity: MILD
Onset: DELAYED
Nervousness Incidence:
1.7%*
Severity: SEVERE
Onset: DELAYED
Blood In The Urine Incidence:
1.7%*
Severity: SEVERE
Onset: DELAYED
Swelling Incidence:
1.7%*
Severity: SEVERE
Onset: DELAYED
Weakness Incidence:
1.8%*
Severity: SEVERE
Onset: DELAYED
Yellow Skin Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Veno-occlusive Disease (VOD) Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Sinusoidal Obstruction Syndrome (SOS) Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Bone Pain Incidence:
2.6%*
Severity: SEVERE
Onset: DELAYED
Chills Incidence:
2.6%*
Severity: SEVERE
Onset: RAPID
Back Pain Incidence:
2.6%*
Severity: SEVERE
Onset: DELAYED
Joint Pain Incidence:
2.6%*
Severity: SEVERE
Onset: DELAYED
Blood Vessel Fluid Leak Incidence:
4.0%*
Severity: SEVERE
Onset: EARLY
Tired Incidence:
4.3%*
Severity: SEVERE
Onset: EARLY
Rapid Breathing Incidence:
4.4%*
Severity: SEVERE
Onset: EARLY
Kidney Failure Incidence:
5.0%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
5.2%*
Severity: SEVERE
Onset: RAPID
High Blood Pressure Incidence:
5.2%*
Severity: SEVERE
Onset: EARLY
Inflamed Colon Incidence:
5.2%*
Severity: SEVERE
Onset: DELAYED
Headache Incidence:
5.2%*
Severity: SEVERE
Onset: EARLY
Tumor Lysis Syndrome (TLS) Incidence:
6.1%*
Severity: SEVERE
Onset: DELAYED
Red Spotted Rash Incidence:
6.1%*
Severity: SEVERE
Onset: DELAYED
Shortness Of Breath Incidence:
6.9%*
Severity: SEVERE
Onset: EARLY
Hand And Foot Syndrome Incidence:
7.0%*
Severity: SEVERE
Onset: DELAYED
Fluid Around The Heart Incidence:
7.8%*
Severity: SEVERE
Onset: DELAYED
Vomiting Incidence:
8.7%*
Severity: SEVERE
Onset: EARLY
Skin Redness Incidence:
11.3%*
Severity: MODERATE
Onset: EARLY
Loose Stools Incidence:
12.2%*
Severity: SEVERE
Onset: EARLY
Fluid Around The Lungs Incidence:
12.2%*
Severity: SEVERE
Onset: DELAYED
Decreased Appetite Incidence:
12.2%*
Severity: SEVERE
Onset: DELAYED
High Bilirubin Level Incidence:
13.0%*
Severity: SEVERE
Onset: DELAYED
Nose Bleed Incidence:
13.0%*
Severity: SEVERE
Onset: DELAYED
Fever Incidence:
13.9%*
Severity: SEVERE
Onset: EARLY
Muscle Pain Incidence:
13.9%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
14.8%*
Severity: SEVERE
Onset: EARLY
Flushing Incidence:
19.1%*
Severity: MILD
Onset: RAPID
Low Blood Pressure Incidence:
19.1%*
Severity: SEVERE
Onset: RAPID
Elevated Hepatic Enzymes Incidence:
36.0-43.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cells Incidence:
63.7%*
Severity: SEVERE
Onset: DELAYED
Anemia Incidence:
75.4%*
Severity: SEVERE
Onset: DELAYED
Low Platelet Count Incidence:
79.8%*
Severity: SEVERE
Onset: DELAYED
Low Lymphocytes Incidence:
82.3%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
87.7%*
Severity: SEVERE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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