Clomipramine Oral Capsule 25Mg Drug Medication Dosage Information
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Clomipramine: Oral capsule (25mg)

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Drug Image file DrugItem_14181.JPG
Clomipramine 25mg Cap
Taro Pharmaceuticals USA Inc
Pill Identification: CLOM 25 CLOM 25,TARO 25 
Drug Image file DrugItem_14181.JPG
Clomipramine 25mg Cap
Taro Pharmaceuticals USA Inc
Pill Identification: CLOM 25 CLOM 25,TARO 25 
Drug Image file DrugItem_1902.JPG
Clomipramine 25mg Cap
Mylan Pharmaceuticals Inc
Pill Identification: MYLAN 3025 MYLAN 3025 
Drug Image file DrugItem_3722.JPG
Clomipramine 25mg Cap
Sandoz Inc
Pill Identification: GG 822 GG 822 

What is this Medicine?

CLOMIPRAMINE (kloe MI pra meen) is an antidepressant. It is used to treat obsessive-compulsive disorder.

CVS Pharmacy Patient Statistics for Clomipramine: Oral capsule(25mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
Select a Medication

Clomipramine Hydrochloride 25mg Capsule

NDC: 516724011
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Obsessive-compulsive Disorder (OCD)

Sometimes used for but not FDA approved for the following conditions:
Autism, Premature Ejaculation, Depression

Storage Information
Protect from moisture
Store at controlled room temperature (between 68 and 77 degrees F)
Clomipramine Hydrochloride 25mg Capsule
Drug Image file DrugItem_1077.JPG
Taro Pharmaceuticals USA Inc
Pill Identification: CLOM 25 CLOM 25,TARO 25 
Shape: capsule
Color: blue
Drug Image file DrugItem_14181.JPG
Taro Pharmaceuticals USA Inc
Pill Identification: CLOM 25 CLOM 25,TARO 25 
Shape: capsule
Color: blue

Reported Side Effects for Clomipramine Hydrochloride 25mg Capsule

Unable To Speak Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Causing To Be Hungry Incidence:
<11.0%*
Severity: MILD
Onset: DELAYED
Weakness Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Increase In Breast Size Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Abnormal Cervical Cells Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Inflammation Of The Lip Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Chills Incidence:
<2.0%*
Severity: MILD
Onset: RAPID
Choreoathetosis Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Conjunctivitis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Cyanosis Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Dysarthria Incidence:
<3.0%*
Severity: MODERATE
Onset: DELAYED
Dystonic Reaction Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Bulging Eyes Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Galactorrhea Incidence:
<4.0%*
Severity: MODERATE
Onset: DELAYED
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Vaginal Infection Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Rapid Heart Rate Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Bundle-branch Block Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Difficulty Swallowing Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Endometrial Hyperplasia Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Intestinal Blockage Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Heart Attack Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Muscle Disease Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Convulsions Incidence:
<2.1%*
Severity: SEVERE
Onset: DELAYED
Fainting Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Large Pupil Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Night Blindness Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Paresis Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Bruises Incidence:
<3.0%*
Severity: MILD
Onset: DELAYED
Pus In Urine Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Dandruff Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Serotonin Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Skin Ulcer Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Stool Discoloration Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Wryneck Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Yawning Incidence:
<3.0%*
Severity: MILD
Onset: EARLY
Glycosuria Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Gynecomastia Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Bad Breath Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Bruise Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Coughing Up Blood Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Hiccups Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Hyperesthesia Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Overactive Reflexes Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Ambras Syndrome Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Hypoesthesia Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Shallow, Slow Breathing Incidence:
<0.1%*
Severity: MODERATE
Onset: RAPID
Impotence (erectile Dysfunction) Incidence:
<20.0%*
Severity: MODERATE
Onset: DELAYED
Increased Urination Incidence:
<6.0%*
Severity: MILD
Onset: EARLY
Inflamed Vocal Cords Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Vocal Cord Spasm Incidence:
<0.1%*
Severity: SEVERE
Onset: RAPID
Vaginal Discharge Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Decreased Sexual Desire Incidence:
<21.0%*
Severity: MILD
Onset: DELAYED
Fast Eye Movements Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Muscle Pain Incidence:
<13.0%*
Severity: MILD
Onset: EARLY
Migraine Incidence:
<3.0%*
Severity: MODERATE
Onset: EARLY
Breast Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Eye Inflammatoin Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Bowel Obstruction Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Heart Failure Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Enlarged Thyroid Gland Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Inflamed Hair Follicles Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Gas Incidence:
<6.0%*
Severity: MILD
Onset: EARLY
Fever Incidence:
<4.0%*
Severity: MILD
Onset: EARLY
Throat Inflammation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Shortness Of Breath Incidence:
<2.0%*
Severity: MODERATE
Onset: EARLY
Depression Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Bladder Infection Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Eye Twitch Incidence:
<2.0%*
Severity: MODERATE
Onset: EARLY
Inflamed Eyes Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Heart Block Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Irregular Heart Rate Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
No Menstrual Periods Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Distressed Incidence:
<3.0%*
Severity: MILD
Onset: EARLY
Mouth Ulcers Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Protein In The Urine Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Sore Throat Incidence:
<14.0%*
Severity: MILD
Onset: DELAYED
Enlarged Lymph Nodes Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Dehydration Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Delirium Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Diabetes Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Overbreathing Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Epididymis Inflammation Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Psoriasis Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Hyperkinesis Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Hyperacusis Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Hostility Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Brain Dysfunction Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Deafness Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Hallucinations Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Inflamed Stomach Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Gum Inflammation Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Inflamed Tongue Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Teeth Grinding Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Hair Loss Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Sleep-Walking Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Skin Discoloration Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Scaly And Itchy Rashes Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Uncontrolled Urination Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Slow Heart Beat Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: RAPID
Photosensitivity Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Perineal Pain Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Stomach Ulcer Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Parosmia Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Suddenly Stopped Heart Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Paranoia Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Pale Skin Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Ear Pain Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Inflamed Colon Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Nighttime Urination Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Coma Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Rash With Pustules Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Double Vision Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Tooth Cavities Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Extra Saliva Production Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Blood In The Urine Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
High Uric Acid Level Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Low Potassium Levels Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Liver Infection Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Underactive Thyroid Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Increased Blood Sugar Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Incoordination Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Mania Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Muscle Cramps Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Vaginal Bleeding Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Urination Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Thoughts Of Suicide Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Inceased Urination Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Psychosis Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Eye Pain Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Elated Mood Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Dyskinesia Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Hoarseness Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
High Cholesterol Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Hemorrhoids Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Gout Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Heartburn Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Light Sensitivity Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Blurred Vision Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Balance Problems Incidence:
>1.0%*
Severity: MILD
Onset: EARLY
Withdrawal Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: DELAYED
Muscle Weakness Incidence:
1.0-2.0%*
Severity: MODERATE
Onset: DELAYED
Nervousness Incidence:
2.0-9.0%*
Severity: MILD
Onset: DELAYED
Paresthesias Incidence:
2.0-9.0%*
Severity: MILD
Onset: DELAYED
Itching Incidence:
2.0-6.0%*
Severity: MILD
Onset: RAPID
Breathing Difficulties Incidence:
2.0-7.0%*
Severity: SEVERE
Onset: RAPID
Hot Flashes Incidence:
2.0-5.0%*
Severity: MODERATE
Onset: EARLY
Sinus Infection Incidence:
2.0-6.0%*
Severity: MILD
Onset: DELAYED
Rapid Muscle Twitches Incidence:
2.0-13.0%*
Severity: MODERATE
Onset: DELAYED
Retaining Urine Incidence:
2.0-7.0%*
Severity: MODERATE
Onset: EARLY
Confusion Incidence:
2.0-3.0%*
Severity: MODERATE
Onset: EARLY
Rapid Heart Rate Incidence:
2.0-4.0%*
Severity: MODERATE
Onset: RAPID
Excessive Mucle Tone Incidence:
2.0-4.0%*
Severity: MODERATE
Onset: DELAYED
Weight Gain Incidence:
2.0-18.0%*
Severity: MILD
Onset: DELAYED
Irritability Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Skin Rash Incidence:
4.0-8.0%*
Severity: MILD
Onset: EARLY
Postural Low Blood Pressure Incidence:
4.0-6.0%*
Severity: MODERATE
Onset: DELAYED
Rapid Heart Rate Incidence:
4.0%*
Severity: MODERATE
Onset: EARLY
Chest Pain Incidence:
4.0-7.0%*
Severity: MODERATE
Onset: EARLY
Ringing In Ears Incidence:
4.0-6.0%*
Severity: MILD
Onset: DELAYED
Metallic Taste Incidence:
4.0-8.0%*
Severity: MILD
Onset: EARLY
Weight Loss Incidence:
5.0%*
Severity: MILD
Onset: DELAYED
Ejaculation Dysfunction Incidence:
6.0-42.0%*
Severity: MODERATE
Onset: DELAYED
Flushing Incidence:
7.0-8.0%*
Severity: MILD
Onset: RAPID
Visual Impairment Incidence:
7.0-18.0%*
Severity: SEVERE
Onset: EARLY
Decreased Memory Incidence:
7.0-9.0%*
Severity: MODERATE
Onset: DELAYED
Rhinitis Incidence:
7.0-12.0%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
7.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
7.0-13.0%*
Severity: MILD
Onset: EARLY
Excessive Sweating Incidence:
9.0-29.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
9.0-33.0%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
11.0-25.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
11.0-13.0%*
Severity: MILD
Onset: EARLY
Decreased Appetite Incidence:
12.0-22.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
13.0-22.0%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
22.0-47.0%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
28.0-52.0%*
Severity: MILD
Onset: EARLY
Shaking Incidence:
33.0-54.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
35.0-39.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
41.0-54.0%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
46.0-54.0%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
63.0-84.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Clomipramine Hydrochloride 25mg Capsule

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Clomipramine Hydrochloride 25mg Capsule(Clomipramine Hydrochloride)
Alcohol and CNS Depressants(Clomipramine Hydrochloride)
Avoid alcohol-containing drinks while taking this medicine. Using this drug along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how this drug affects you, and especially if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Major Lifestyle Interaction
Marijuana and Clomipramine Hydrochloride 25mg Capsule(Clomipramine Hydrochloride)
Marijuana and Tricyclic antidepressants(Clomipramine Hydrochloride)
Do not take Marijuana, Medical and Tricyclic Antidepressants together without talking to your health care provider. Taking these drugs together might increase the risk of high blood pressure or heart rate, nervousness, palpitations, problems with sleep, severe headache, or other side effects.
Moderate Lifestyle Interaction
Tobacco and Clomipramine Hydrochloride 25mg Capsule(Clomipramine Hydrochloride)
Tobacco and Tricyclic antidepressants(Clomipramine Hydrochloride)
Tobacco smoking may reduce the effectiveness of this drug in treating your condition. Tobacco smoke contains substances that speed the removal of this drug from the body, which in theory can make this drug less effective. Alternatively, if you take this drug and suddenly stop Tobacco smoking, you may experience drug-related side effects like confusion, constipation, dizziness, difficulty with urination, dry mouth and eyes or drowsiness. Make sure your prescriber is aware that you smoke Tobacco or if you plan to stop smoking.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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Patient Experiences with Clomipramine

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