They need to know if you have any of these conditions: -brain tumor -cigarette smoker -constipation or other intestinal problems -drink more than 3 alcohol containing drinks per day -drug abuse or addiction -kidney disease -lung or breathing disease, like asthma -recent head injury -stomach ulcers -an unusual or allergic reaction to oxycodone, codeine, ibuprofen, aspirin, other NSAIDs, other medicines, foods, dyes, or preservatives -pregnant or trying to get pregnant -breast-feeding
Take this medicine by mouth with a full glass of water. Follow the directions on the prescription label. You can take it with or without food. If it upsets your stomach, take it with food. Take your medicine at regular intervals. Do not take your medicine more often than directed.
A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.
Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.
Do not take this medication with any of the following medicines:
-cidofovir -ketorolacThis medicine may interact with the following medications:
-alcohol -antihistamines for allergy, cough and cold -antiviral medicines for HIV or AIDS -aspirin and aspirin-like drugs -atropine -certain antibiotics like clarithromycin, erythromycin, linezolid, rifampin -certain medicines for anxiety or sleep -certain medicines for bladder problems like oxybutynin, tolterodine -certain medicines for blood pressure, heart disease, irregular heart beat -certain medicines for depression like amitriptyline, fluoxetine, lithium, sertraline -certain medicines for fungal infections like ketoconazole, itraconazole, voriconazole -certain medicines for migraine headache like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan -certain medicines for nausea or vomiting like dolasetron, ondansetron, palonosetron -certain medicines for Parkinson's disease like benztropine, trihexyphenidyl -certain medicines for seizures like phenobarbital, primidone -certain medicines for stomach problems like dicyclomine, hyoscyamine -certain medicines for travel sickness like scopolamine -certain medicines to treat or prevent blood clots like warfarin -diuretics -general anesthetics like halothane, isoflurane, methoxyflurane, propofol -ipratropium -local anesthetics like lidocaine, pramoxine, tetracaine -MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate -medicines that relax muscles for surgery -methotrexate -methylene blue -NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen -nilotinib -other narcotic medicines for pain or cough -pemetrexed -phenothiazines like chlorpromazine, mesoridazine, prochlorperazine, thioridazine -steroid medicines like prednisone or cortisone
What should I watch for while using this medicine?
Tell your doctor or health care professional if your pain does not go away, if it gets worse, or if you have new or a different type of pain. You may develop tolerance to the medicine. Tolerance means that you will need a higher dose of the medicine for pain relief. Tolerance is normal and is expected if you take the medicine for a long time.
Do not suddenly stop taking your medicine because you may develop a severe reaction. Your body becomes used to the medicine. This does NOT mean you are addicted. Addiction is a behavior related to getting and using a drug for a non-medical reason. If you have pain, you have a medical reason to take pain medicine. Your doctor will tell you how much medicine to take. If your doctor wants you to stop the medicine, the dose will be slowly lowered over time to avoid any side effects.
There are different types of narcotic medicines (opiates). If you take more than one type at the same time or if you are taking another medicine that also causes drowsiness, you may have more side effects. Give your health care provider a list of all medicines you use. Your doctor will tell you how much medicine to take. Do not take more medicine than directed. Call emergency for help if you have problems breathing or unusual sleepiness.
Do not take other medicines that contain aspirin, ibuprofen, or naproxen with this medicine. Side effects such as stomach upset, nausea, or ulcers may be more likely to occur. Many medicines available without a prescription should not be taken with this medicine.
This medicine can cause ulcers and bleeding in the stomach and intestines at any time during treatment. This can happen with no warning and may cause death. There is increased risk with taking this medicine for a long time. Smoking, drinking alcohol, older age, and poor health can also increase risks. Call your doctor right away if you have stomach pain or blood in your vomit or stool.
This medicine does not prevent heart attack or stroke. In fact, this medicine may increase the chance of a heart attack or stroke. The chance may increase with longer use of this medicine and in people who have heart disease. If you take aspirin to prevent heart attack or stroke, talk with your doctor or health care professional.
You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.
This medicine will cause constipation. Try to have a bowel movement at least every 2 to 3 days. If you do not have a bowel movement for 3 days, call your doctor or health care professional.
Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.
What side effects may I notice from receiving this medicine?
Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue -breathing problems -confusion -signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark-brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eye, gums, or nose -signs and symptoms of a blood clot such as breathing problems; changes in vision; chest pain; severe, sudden headache; pain, swelling, warmth in the leg; trouble speaking; sudden numbness of the face, arm, or leg -signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin -signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired -trouble passing urine or change in the amount of urine -unexplained weight gain or swelling Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
Keep out of the reach of children. This medicine can be abused. Keep your medicine in a safe place to protect it from theft. Do not share this medicine with anyone. Selling or giving away this medicine is dangerous and against the law.
This medicine may cause accidental overdose and death if it taken by other adults, children, or pets. Mix any unused medicine with a substance like cat litter or coffee grounds. Then throw the medicine away in a sealed container like a sealed bag or a coffee can with a lid. Do not use the medicine after the expiration date.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Keep container tightly closed.