Complera Oral Tablet 200-25-300Mg Drug Medication Dosage Information
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COMPLERA: Oral tablet (200-25-300mg)

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Drug Image file DrugItem_16670.JPG
COMPLERA Tablet
Gilead Sciences Inc
Pill Identification: GSI 

What is this Medicine?

EMTRICITABINE; RILPIVIRINE; TENOFOVIR DISOPROXIL FUMARATE (em tri SIT uh bean; ril pi VIR een; te NOE fo veer) is three antiretroviral medicines in one tablet. It is used to treat HIV. This medicine is not a cure for HIV. It will not stop the spread of HIV to others.

CVS Pharmacy Patient Statistics for COMPLERA: Oral tablet(200-25-300mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information

COMPLERA 200mg-25mg-300mg Tablet

NDC: 619581101
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Human Immunodeficiency Virus (HIV) Infection

Sometimes used for but not FDA approved for the following conditions:
Human Immunodeficiency Virus (HIV) Prophylaxis

Storage Information
Store in original container
Store at 77 degrees F; excursions permitted to 59-86 degrees F
COMPLERA 200mg-25mg-300mg Tablet
Drug Image file DrugItem_16670.JPG
Gilead Sciences Inc
Pill Identification: GSI 
Shape: oblong
Color: pink,purple

Reported Side Effects for COMPLERA 200mg-25mg-300mg Tablet

Elevated Hepatic Enzymes Incidence:
<4.0%*
Severity: MODERATE
Onset: DELAYED
Glomerulonephritis Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Darkened Skin Patches Incidence:
<32.0%*
Severity: MILD
Onset: DELAYED
Decreased Appetite Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Cholecystitis Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Gallstones Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Drowsiness Incidence:
<14.0%*
Severity: MILD
Onset: EARLY
High Bilirubin Level Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
High Cholesterol Incidence:
<13.0%*
Severity: MODERATE
Onset: DELAYED
High Triglycerides Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Kidney Stones Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Thoughts Of Suicide Incidence:
0.6%*
Severity: SEVERE
Onset: DELAYED
Upset Stomach Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Skin Rash Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Nightmares Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
1.0-5.6%*
Severity: SEVERE
Onset: DELAYED
Inability To Sleep Incidence:
2.0-10.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
2.0-19.4%*
Severity: MILD
Onset: EARLY
Sore Throat Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Back Pain Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Nervousness Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Joint Pain Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Rhinitis Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Sinus Infection Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Stomach Pain Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Paresthesias Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Vomiting Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Cough Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Fever Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Inflamed Nerve Incidence:
>5.0%*
Severity: MODERATE
Onset: DELAYED
Muscle Pain Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Nerve Pain Incidence:
>5.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Infection Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Anemia Incidence:
7.0%*
Severity: MODERATE
Onset: DELAYED
Dysphoria Incidence:
9.0%*
Severity: MODERATE
Onset: EARLY
Loose Stools Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for COMPLERA 200mg-25mg-300mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and COMPLERA 200mg-25mg-300mg Tablet(Tenofovir Disoproxil Fumarate)
Alcohol and Tenofovir(Tenofovir Disoproxil Fumarate)
Do not take these drugs together without approval from your prescriber. Taking these drugs together may decrease the effectiveness of your HIV medicines. Notify your health care provider if you notice your medicines not working as well of you.
Moderate Lifestyle Interaction
Marijuana and COMPLERA 200mg-25mg-300mg Tablet(Emtricitabine)
Marijuana and Nucleoside reverse transcriptase inhibitors(Emtricitabine)
Although an interaction is possible, these drugs may be used together. In therory, side effects from Marijuana, Medical may get worse if you take Anti-retroviral nucleoside reverse transcriptase inhibitors (NRTIs). However, the importance of this interaction is not known. Notify your health care provider if you notice increased fatigue, nausea, vomiting, or any other unusual effects.
Moderate Lifestyle Interaction
Grapefruit juice and COMPLERA 200mg-25mg-300mg Tablet(Tenofovir Disoproxil Fumarate)
Grapefruit juice and Tenofovir(Tenofovir Disoproxil Fumarate)
Although an interaction is possible, these drugs are sometimes used together. Side effects may increase if these drugs are taken together. If you notice any new or worsening side effects, contact your prescriber immediately.
Moderate Lifestyle Interaction
Marijuana and COMPLERA 200mg-25mg-300mg Tablet(Tenofovir Disoproxil Fumarate)
Marijuana and Nucleotide reverse transcriptase inhibitors(Tenofovir Disoproxil Fumarate)
Although an interaction is possible, these drugs may be used together. In therory, side effects from Marijuana, Medical may get worse if you take Anti-retroviral nucleotide reverse transcriptase inhibitors. However, the importance of this interaction is not known. Notify your health care provider if you notice increased fatigue, nausea, vomiting, or any other unusual effects.
Moderate Lifestyle Interaction
Grapefruit juice and COMPLERA 200mg-25mg-300mg Tablet(Rilpivirine)
Grapefruit juice and Rilpivirine(Rilpivirine)
Side effects from Rilpivirine may get worse if you take Grapefruit juice. Grapefruit juice may decrease the elimination of Rilpivirine from the body, and increase the amount of Rilpivirine in the bloodstream. Your prescriber may decide that taking these drugs together is beneficial for you based on your health conditions. Discuss your drug regimen and health conditions with your health care provider.
Moderate Lifestyle Interaction
Marijuana and COMPLERA 200mg-25mg-300mg Tablet(Rilpivirine)
Marijuana and Non-nucleoside reverse transcriptase inhibitors(Rilpivirine)
Although an interaction is possible, these drugs may be used together. In therory, side effects from Marijuana, Medical may get worse if you take Anti-retroviral non-nucleoside reverse transcriptase inhibitors (NNRTIs). However, the importance of this interaction is not known. Notify your health care provider if you notice increased fatigue, nausea, vomiting, or any other unusual effects.
Pregnancy & Lactation Information
FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
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