Crixivan Oral Capsule 400Mg Drug Medication Dosage Information
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Crixivan: Oral capsule (400mg)

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Drug Image file DrugItem_1111.JPG
Crixivan 400mg Cap
Merck Sharp & Dohme Corp., a Subsidiary of Merck & Co., Inc.
Pill Identification: CRIXIVAN 400 mg 

What is this Medicine?

INDINAVIR (in DIN a veer) is an antiretroviral medicine. It is used with other medicines to treat HIV. This medicine is not a cure for HIV. It will not stop the spread of HIV to others.

In-Depth Information

Crixivan 400mg Capsule

NDC: 000060573
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Human Immunodeficiency Virus (HIV) Infection

Storage Information
Store at room temperature (between 59 to 86 degrees F)
Store and dispense in original container
Protect from moisture
Crixivan 400mg Capsule
Drug Image file DrugItem_1111.JPG
Merck Sharp & Dohme Corp., a Subsidiary of Merck & Co., Inc.
Pill Identification: CRIXIVAN 400 mg 
Shape: capsule
Color: white

Reported Side Effects for Crixivan 400mg Capsule

Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Bleeding Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Intestinal Bleeding Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Bleeding In The Brain Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Heart Attack Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Blood Vessels Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Urine Stones Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
<4.9%*
Severity: MODERATE
Onset: DELAYED
Bruise Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Liver Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Kidney Inflammation Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Darkened Skin Patches Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Diabetic Ketoacidosis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Diabetes Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Depression Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Erythema Multiforme Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Joint Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Hemolytic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Hair Loss Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Stevens-Johnson Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Anemia Incidence:
0.6%*
Severity: MODERATE
Onset: DELAYED
Increased Blood Sugar Incidence:
0.9%*
Severity: MODERATE
Onset: DELAYED
Low Platelet Count Incidence:
0.9%*
Severity: MODERATE
Onset: DELAYED
Skin Rash Incidence:
1.2%*
Severity: MILD
Onset: EARLY
Yellow Skin Incidence:
1.5%*
Severity: MODERATE
Onset: DELAYED
Fever Incidence:
1.5%*
Severity: MILD
Onset: EARLY
Cough Incidence:
1.5%*
Severity: MILD
Onset: DELAYED
Painful Urination Incidence:
1.5%*
Severity: MODERATE
Onset: EARLY
Upset Stomach Incidence:
1.5%*
Severity: MILD
Onset: EARLY
Feeling Sick Incidence:
2.1%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
2.1%*
Severity: MILD
Onset: DELAYED
Causing To Be Hungry Incidence:
2.1%*
Severity: MILD
Onset: DELAYED
Tired Incidence:
2.1%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
2.4%*
Severity: MILD
Onset: EARLY
Low White Blood Cells Incidence:
2.4%*
Severity: MODERATE
Onset: DELAYED
Metallic Taste Incidence:
2.7%*
Severity: MILD
Onset: EARLY
Heartburn Incidence:
2.7%*
Severity: MILD
Onset: DELAYED
Decreased Appetite Incidence:
2.7%*
Severity: MILD
Onset: DELAYED
Lightheadedness Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
3.3%*
Severity: MILD
Onset: EARLY
Itching Incidence:
4.2%*
Severity: MILD
Onset: RAPID
Headache Incidence:
5.4%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
8.4%*
Severity: MILD
Onset: EARLY
Back Pain Incidence:
8.4%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
11.7%*
Severity: MILD
Onset: EARLY
Kidney Stones Incidence:
12.4-29.0%*
Severity: MODERATE
Onset: DELAYED
High Bilirubin Level Incidence:
14.0%*
Severity: MODERATE
Onset: DELAYED
Stomach Pain Incidence:
16.6%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Crixivan 400mg Capsule

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Food and Crixivan 400mg Capsule(Indinavir Sulfate)
Food and Indinavir Sulfate(Indinavir Sulfate)
Foods high in calories, fat, and protein may decrease the absorption of Indinavir from your stomach. Lighter meals, such as dry toast with jelly, apple juice, and coffee with skim milk, may cause little or no change in the activity of indinavir.
Moderate Lifestyle Interaction
Grapefruit juice and Crixivan 400mg Capsule(Indinavir Sulfate)
Grapefruit juice and Indinavir Sulfate(Indinavir Sulfate)
Do not drastically change the amount of grapefruit juice you drink or try to avoid grapefruit juice while taking Indinavir, unless advised differently by your healthcare professional. Taking grapefruit juice and Indinavir together may result in decreased absorption of Indinavir.
Moderate Lifestyle Interaction
Marijuana and Crixivan 400mg Capsule(Indinavir Sulfate)
Marijuana and Protease inhibitors(Indinavir Sulfate)
Although an interaction is possible, these drugs may be used together. In therory, side effects from Marijuana, Medical may get worse if you take Anti-retroviral protease inhibitors. However, the importance of this interaction is not known. Notify your health care provider if you notice increased fatigue, nausea, vomiting, or any other unusual effects.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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