Decongestants With Analgesics Oral Tablet, Extended Release 220-120Mg Drug Medication Dosage Information
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Decongestants with Analgesics: Oral tablet, extended release (220-120mg)

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Drug Image file DrugItem_14908.JPG
Aleve-D Sinus & Cold ER Caplet
Bayer Corp Consumer Care Div
Pill Identification: ALEVE CS 
Drug Image file DrugItem_17922.JPG
Aleve-D Sinus & Cold ER Caplet
Bayer Corp Consumer Care Div
Pill Identification: ALEVE CS 

What is this Medicine?

NAPROXEN; PSEUDOEPHEDRINE (na PROX en; soo doe e FED rin) is a combination of pain reliever and a decongestant. It is used to treat the aches, pains, and congestion of a cold. This medicine will not treat an infection.

In-Depth Information
Select a Medication

Leader All Day Cold & Sinus Extended-Release Tablet

NDC: 372050435
  • Over the Counter
    (Prescription Not Required)
  • Not a Controlled Drug
    (CSA Schedule)




FDA approved for the following conditions:
Fever, Mild Pain, Headache, Common Cold, Nasal Congestion

Storage Information
Store at controlled room temperature (between 68 and 77 degrees F)
Leader All Day Cold & Sinus Extended-Release Tablet
Daily Life Interactions for Leader All Day Cold & Sinus Extended-Release Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Leader All Day Cold & Sinus Extended-Release Tablet(Naproxen Sodium)
Alcohol and Nonsteroidal antiinflammatory drugs (systemic)(Naproxen Sodium)
Side effects from this drug may get worse if you drink alcohol-containing drinks. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. It is best to limit or avoid alcohol containing drinks while taking this drug, even with short term use. Many non-prescription products for headaches, pain, arthritis, or sinus pain contain drugs that may cause stomach problems along with alcohol; closely read labels before taking any medicines with alcohol-containing drinks.
Moderate Lifestyle Interaction
Tobacco and Leader All Day Cold & Sinus Extended-Release Tablet(Naproxen Sodium)
Tobacco and Nonsteroidal antiinflammatory drugs (systemic)(Naproxen Sodium)
Side effects from Nonsteroidal anti-inflammatory drugs may get worse if you use tobacco-containing products such as cigarettes. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. Many non-prescription products contain NSAIDs; closely read labels before taking any medicines. Eye or Skin products containing NSAIDs should not interact with tobacco.
Moderate Lifestyle Interaction
Marijuana and Leader All Day Cold & Sinus Extended-Release Tablet(Naproxen Sodium)
Marijuana and Nonsteroidal antiinflammatory drugs (systemic)(Naproxen Sodium)
Although an interaction is possible, these drugs may be used together. In therory, the actions of Marijuana, Medical may be decreased if you take Nonsteroidal Antiinflammatory Drugs (NSAIDs). However, the importance of this interaction is not known. Patients receiving this drug combination may notice decreased euphoria and heart rate.
Moderate Lifestyle Interaction
Caffeine-containing Foods/Beverages and Leader All Day Cold & Sinus Extended-Release Tablet(Pseudoephedrine Hydrochloride)
Caffeine-containing Foods/Beverages and Pseudoephedrine(Pseudoephedrine Hydrochloride)
Limit caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Pseudoephedrine. Also avoid medicines containing additional Caffeine whenever possible. Side effects from Pseudoephedrine may get worse if you take excessive Caffeine. Taking a high amount of Caffeine can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, tremor, or other side effects.
Learning More About
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Patient Experiences with Decongestants with Analgesics

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