Depo-Estradiol Solution For Injection 5Mg Drug Medication Dosage Information
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Depo-Estradiol: Solution for injection (5mg)

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Depo-Estradiol 5mg/ml for Inj

What is this Medicine?

ESTRADIOL (es tra DYE ole) is an estrogen. It is used to treat the symptoms of low hormone levels in menopausal women. It is used to treat women who have had their ovaries removed or who have ovaries that do not work well. It helps to treat hot flashes and vaginal problems. It is also used to treat men with some kinds of prostate cancer.

CVS Pharmacy Patient Statistics for Depo-Estradiol: Solution for injection(5mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information

Depo-Estradiol 5mg/ml in Oil for Injection

NDC: 000090271
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved





Storage Information
Store at controlled room temperature (between 68 and 77 degrees F)
Depo-Estradiol 5mg/ml in Oil for Injection

Reported Side Effects for Depo-Estradiol 5mg/ml in Oil for Injection

Yeast Infection Incidence:
<8.0%*
Severity: MODERATE
Onset: DELAYED
Endometrial Hyperplasia Incidence:
<10.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Weight Gain Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Breakthrough Bleeding Incidence:
>10.0%*
Severity: MILD
Onset: DELAYED
Menstrual Cramps Incidence:
>10.0%*
Severity: MILD
Onset: DELAYED
Breast Pain Incidence:
>10.0%*
Severity: MILD
Onset: DELAYED
Stomach Pain Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Depo-Estradiol 5mg/ml in Oil for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Tobacco and Depo-Estradiol 5mg/ml in Oil for Injection(Estradiol Cypionate)
Tobacco and Estrogens in Hormonal Contraceptives(Estradiol Cypionate)
You are strongly advised not to smoke while taking this medication. Tobacco smoking can increase the risk of a blood clot, stroke, heart attack or other serious problem while taking this medication. This is especially true if you are a female over 35 years of age or if you smoke > 15 cigarettes per day. While taking this medication, you should report any of the following "ACHES" to your prescriber immediately: Abdominal pain, Chest pain, severe or frequent Headaches or migraines; Eye pain or Severe leg pain in the calves or the thighs.
Minor Lifestyle Interaction
Grapefruit juice and Depo-Estradiol 5mg/ml in Oil for Injection(Estradiol Cypionate)
Grapefruit juice and Estrogens(Estradiol Cypionate)
Grapefruit juice and grapefruit-containing foods may increase the side effects of estrogen in some females, such as nausea, breast tenderness, headache or fluid retention. There may be no interaction. Do not significantly change your grapefruit intake while taking estrogens for hormone replacement therapy or as part of hormonal birth control products. Report any unusual side effects, like unusual non-menstrual vaginal bleeding, promptly for evaluation.
Pregnancy & Lactation Information
FIRST Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

SECOND Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

THIRD Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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