Vimovo Oral Tablet, Gastro-Resistant 500-20Mg Drug Medication Dosage Information
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Vimovo: Oral tablet, gastro-resistant (500-20mg)

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Most Commonly Used
Drug Image file DrugItem_15138.JPG
Vimovo 500mg-20mg DR Tab
AstraZeneca LP
Pill Identification: 500/20 

What is this Medicine?

ESOMEPRAZOLE; NAPROXEN (es oh ME pray zol; na PROX en) is two medicines together. Naproxen is a non-steroidal anti-inflammatory drug (NSAID). It is used to treat the pain of arthritis. Esomeprazole is a proton pump inhibitor (PPI). It is used to prevent stomach problems from the naproxen.

CVS/pharmacy Patient Statistics for Vimovo: Oral tablet, gastro-resistant(500-20mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
Select a Medication

Vimovo 500mg-20mg Delayed-Release Tablet

NDC: 001860520
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Ankylosing Spondylitis, Rheumatoid Arthritis, Osteoarthritis

Storage Information
Store in original container
Protect from moisture
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Vimovo 500mg-20mg Delayed-Release Tablet
Drug Image file DrugItem_15138.JPG
AstraZeneca LP
Pill Identification: 500/20 
Shape: oval
Color: yellow

Reported Side Effects for Vimovo 500mg-20mg Delayed-Release Tablet

Eosinophilia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
<15.0%*
Severity: MODERATE
Onset: DELAYED
Confusion Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Low White Blood Cell Counts Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
High White Blood Cells Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Blood In The Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Hole In Intestines Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
No White Blood Cells Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Kidney Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Skin Rash Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Pseudoporphyria Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Photosensitivity Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Stomach Ulcer Incidence:
<6.0%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
<3.0%*
Severity: MODERATE
Onset: EARLY
Muscle Weakness Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Melena Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Feeling Sick Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Rash With Pustules Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Kidney Inflammation Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Decreased Thinking Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Vomiting Of Blood Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Deafness Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hallucinations Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Glomerulonephritis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Heartburn Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Throat Inflammation Incidence:
<4.0%*
Severity: MODERATE
Onset: DELAYED
Drowsiness Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Angioedema Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Anemia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Severe Allergy Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Hair Loss Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Distressed Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Mouth Ulcers Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Itching Incidence:
<9.0%*
Severity: MILD
Onset: RAPID
Inability To Sleep Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Migraine Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Nephrotic Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cells Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Sore Throat Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Diaphoresis Incidence:
1.0-3.0%*
Severity: MILD
Onset: EARLY
Joint Pain Incidence:
1.0%*
Severity: MILD
Onset: DELAYED
Bruises Incidence:
1.0-3.0%*
Severity: MILD
Onset: DELAYED
Intestinal Bleeding Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Cough Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Metallic Taste Incidence:
2.0%*
Severity: MILD
Onset: EARLY
Sinus Infection Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Stomach Pain Incidence:
2.0-6.0%*
Severity: MILD
Onset: EARLY
Bruise Incidence:
3.0-9.0%*
Severity: MILD
Onset: DELAYED
Constipation Incidence:
3.0%*
Severity: MODERATE
Onset: DELAYED
Shortness Of Breath Incidence:
3.0-9.0%*
Severity: MODERATE
Onset: EARLY
Ringing In Ears Incidence:
3.0-9.0%*
Severity: MILD
Onset: DELAYED
Headache Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Fluid Retention Incidence:
3.0-9.0%*
Severity: MODERATE
Onset: DELAYED
Gas Incidence:
4.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
5.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
6.0%*
Severity: MILD
Onset: EARLY
Inflamed Stomach Incidence:
17.0-19.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
18.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Vimovo 500mg-20mg Delayed-Release Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Vimovo 500mg-20mg Delayed-Release Tablet(Naproxen)
Alcohol and Nonsteroidal antiinflammatory drugs (systemic)(Naproxen)
Side effects from this drug may get worse if you drink alcohol-containing drinks. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. It is best to limit or avoid alcohol containing drinks while taking this drug, even with short term use. Many non-prescription products for headaches, pain, arthritis, or sinus pain contain drugs that may cause stomach problems along with alcohol; closely read labels before taking any medicines with alcohol-containing drinks.
Moderate Lifestyle Interaction
Tobacco and Vimovo 500mg-20mg Delayed-Release Tablet(Naproxen)
Tobacco and Nonsteroidal antiinflammatory drugs (systemic)(Naproxen)
Side effects from Nonsteroidal anti-inflammatory drugs may get worse if you use tobacco-containing products such as cigarettes. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. Many non-prescription products contain NSAIDs; closely read labels before taking any medicines. Eye or Skin products containing NSAIDs should not interact with tobacco.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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