Diltiazem Oral Tablet 120Mg Drug Medication Dosage Information
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Diltiazem: Oral tablet (120mg)

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Drug Image file DrugItem_1892.JPG
Diltiazem 120mg Tab
Teva Pharmaceuticals USA
Pill Identification: 93 321 
Drug Image file DrugItem_1035.JPG
Diltiazem 120mg Tab
Mylan Pharmaceuticals Inc.
Pill Identification: M 525 

What is this Medicine?

DILTIAZEM (dil TYE a zem) is a calcium-channel blocker. It affects the amount of calcium found in your heart and muscle cells. This relaxes your blood vessels, which can reduce the amount of work the heart has to do. This medicine is used to treat chest pain caused by angina.

CVS Pharmacy Patient Statistics for Diltiazem: Oral tablet(120mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Diltiazem Hydrochloride 120mg Tablet

NDC: 000930321
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Angina, Atrial Flutter, Variant Angina, Paroxysmal Supraventricular Tachycardia (PSVT), Atrial Fibrillation

Sometimes used for but not FDA approved for the following conditions:
Diabetic Nephropathy, Migraine Prophylaxis, Proteinuria, Hypertension, Unstable Angina, Cardiomyopathy

Storage Information
Store at room temperature (between 59 to 86 degrees F)
Diltiazem Hydrochloride 120mg Tablet
Drug Image file DrugItem_1892.JPG
Teva Pharmaceuticals USA
Pill Identification: 93 321 
Shape: oblong
Color: orange

Reported Side Effects for Diltiazem Hydrochloride 120mg Tablet

Elevated Hepatic Enzymes Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Metallic Taste Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
<10.0%*
Severity: MILD
Onset: EARLY
Diaphoresis Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Conjunctivitis Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Confusion Incidence:
<2.0%*
Severity: MODERATE
Onset: EARLY
Chest Pain Incidence:
<2.0%*
Severity: MODERATE
Onset: EARLY
Weakness Incidence:
<4.0%*
Severity: MILD
Onset: DELAYED
Arthropathy Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Loss Of Memory Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Inflamed Blood Vessels Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Fainting Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Inceased Urination Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Nerve Pain Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
<15.0%*
Severity: MODERATE
Onset: DELAYED
Muscle Disease Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Muscle Cramps Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Infection Incidence:
<6.0%*
Severity: MILD
Onset: DELAYED
Increased Blood Sugar Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Intestinal Bleeding Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Bundle-branch Block Incidence:
<2.0%*
Severity: MODERATE
Onset: EARLY
Lack Of Heartbeat Incidence:
<2.0%*
Severity: SEVERE
Onset: RAPID
Stomach Pain Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
<2.2%*
Severity: MILD
Onset: EARLY
Red, Pimple Rash Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Weight Gain Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Lyell'S Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
<2.0%*
Severity: MODERATE
Onset: RAPID
Rhinitis Incidence:
<9.6%*
Severity: MILD
Onset: EARLY
Retinopathy Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Kidney Failure Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Bruises Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Photosensitivity Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Red Spotted Rash Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Stomach Ulcer Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
<2.0%*
Severity: MODERATE
Onset: EARLY
Eye Irritation Incidence:
<2.0%*
Severity: MILD
Onset: RAPID
Bleeding Within The Eye Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Nighttime Urination Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Impotence (erectile Dysfunction) Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Excessive Mucle Tone Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Hallucinations Incidence:
<2.0%*
Severity: MODERATE
Onset: EARLY
Gingival Hyperplasia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Flushing Incidence:
<1.7%*
Severity: MILD
Onset: RAPID
Belching Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Gas Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Exfoliative Dermatitis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Erythema Multiforme Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Nose Bleed Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Shortness Of Breath Incidence:
<6.0%*
Severity: MODERATE
Onset: EARLY
Upset Stomach Incidence:
<6.0%*
Severity: MILD
Onset: EARLY
Menstrual Cramps Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Drowsiness Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Bladder Infection Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Constipation Incidence:
<3.6%*
Severity: MODERATE
Onset: DELAYED
Inflamed Colon Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Slow Heart Beat Incidence:
<3.6%*
Severity: SEVERE
Onset: RAPID
Bone Pain Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Heart Block Incidence:
<3.3%*
Severity: SEVERE
Onset: EARLY
Irregular Heart Rate Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Irregular Heart Beat Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Joint Pain Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Decreased Appetite Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Chest Pain Incidence:
<2.0%*
Severity: MODERATE
Onset: EARLY
Lazy Eye Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Hair Loss Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Dry Mouth Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Balance Problems Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Rapid Heart Rate Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Rapid Heart Rate Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Vaginal Infection Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Hives Incidence:
<2.0%*
Severity: MILD
Onset: RAPID
Shaking Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Ringing In Ears Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Stevens-Johnson Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Sinus Infection Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Itching Incidence:
<2.0%*
Severity: MILD
Onset: RAPID
Kidney Stones Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Stuffy Nose Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Muscle Pain Incidence:
<2.3%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Low Blood Pressure Incidence:
<4.3%*
Severity: MODERATE
Onset: RAPID
High Uric Acid Level Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Heart Failure Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Headache Incidence:
<8.9%*
Severity: MILD
Onset: EARLY
Gout Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Cough Incidence:
1.0-3.0%*
Severity: MILD
Onset: DELAYED
Skin Rash Incidence:
1.0-2.0%*
Severity: MILD
Onset: EARLY
Sore Throat Incidence:
1.4-6.0%*
Severity: MILD
Onset: DELAYED
Back Pain Incidence:
1.7-2.9%*
Severity: MILD
Onset: DELAYED
Flu Incidence:
2.0-2.3%*
Severity: MILD
Onset: DELAYED
Tired Incidence:
4.8%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Diltiazem Hydrochloride 120mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Grapefruit juice and Diltiazem Hydrochloride 120mg Tablet(Diltiazem Hydrochloride)
Grapefruit juice and Diltiazem(Diltiazem Hydrochloride)
Although less likely than with some other Calcium-Channel Blockers, Grapefruit juice and grapefruit-containing foods may increase the side effects of Calcium-Channel Blockers. Do not significantly increase grapefruit juice intake while taking this drug, or avoid grapefruit juice if possible. If your heart rate or blood pressure drops too low while taking this medicine, you may become dizzy or feel faint; do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away while taking this medicine. If you notice new or increased swelling of your legs or ankles, tell your health care provider.
Moderate Lifestyle Interaction
Marijuana and Diltiazem Hydrochloride 120mg Tablet(Diltiazem Hydrochloride)
Marijuana and Diltiazem(Diltiazem Hydrochloride)
Diltiazem can theoretically decrease the elimination of Marijuana, Medical from the body. Side effects from Marijuana, Medical may worsen if you take DIltiazem. You may feel drowsy or more tired. Do not drive or operate machinery until you know how these drugs affect you. Contact your health care provider immediately if you notice slurred speech, confusion, increases heart rate, or palpitations while taking Marijuana, Medical.
Moderate Lifestyle Interaction
Alcohol and Diltiazem Hydrochloride 120mg Tablet(Diltiazem Hydrochloride)
Alcohol and Antihypertensives(Diltiazem Hydrochloride)
Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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