show timeout overlay link

Your Session Is About to Expire

This online session is about to expire due to inactivity. Click Continue to return to page.

  • Weekly Ad

Diphenhydramine: Oral capsule

Also see:
  • Reported side effects
  • Daily life interactions

Available Strengths
Drug Image file DrugItem_3417.JPG
Diphenhydramine 25mg Cap
Ivax Corporation a Division of Teva USA
Pill Identification: LNK 25 
Drug Image file DrugItem_10992.JPG
Diphenhydramine 50mg Cap
Barr Laboratories Inc a Division of Teva USA
Pill Identification: barr 059 
Drug Image file DrugItem_14720.JPG
Allergy 25mg Cap
AmerisourceBergen Corporation
Pill Identification: L462 L462 
Drug Image file DrugItem_7790.JPG
Diphenhydramine 25mg Cap
United Research Laboratories, Inc. a subsidiary of Sun Pharmaceutical Industries, Inc.
Pill Identification: K 115 
Drug Image file DrugItem_2618.JPG
Diphenhydramine 50mg Cap
Mylan Institutional LLC formerly UDL Laboratories Inc
Pill Identification: barr 059 
Drug Image file DrugItem_12464.JPG
Diphenhydramine 25mg Cap
PD-RX Pharmaceuticals
Pill Identification: LNK 25 
Drug Image file DrugItem_15353.JPG
Allergy 25mg Capsule
CVS Pharmacy, Inc
Pill Identification: 44-107 44-107 
Drug Image file DrugItem_11886.JPG
Diphenhydramine 25mg Cap
Eon Labs Inc a Division of Sandoz
Pill Identification: E648 E648 
Drug Image file DrugItem_9828.JPG
Diphenhydramine 50mg Cap
Eon Labs Inc a Division of Sandoz
Pill Identification: E649 E649 
Drug Image file DrugItem_4858.JPG
Diphenhydramine 50mg Cap
Qualitest Pharmaceuticals Inc
Pill Identification: LOGO 21 
Drug Image file DrugItem_7500.JPG
Diphenhydramine 25mg Cap
Qualitest Pharmaceuticals Inc
Pill Identification: K 115 
Drug Image file DrugItem_13565.JPG
Diphenhist 25mg Cap
Rugby Laboratories a Division of The Harvard Drug Group, LLC
Pill Identification: LOGO 20 
Drug Image file DrugItem_13290.JPG
Allergy Medicine 25mg Cap
Select Brand
Pill Identification: 44-107 44-107 
Drug Image file DrugItem_9433.JPG
Wal-dryl Allergy Cap
Walgreen Co
Pill Identification: 44-107 44-107 
Drug Image file DrugItem_13321.JPG
Allergy 25mg Capsule
Publix Super Markets, Inc
Pill Identification: L462 L462 
Drug Image file DrugItem_17323.JPG
Diphenhydramine 50mg Cap
Qualitest Pharmaceuticals Inc
Pill Identification: LOGO 21 
How This Drug Works
Antihistamines, H1
Histamine antagonists or antihistamines are drugs that relieve allergy symptoms. Histamine is a chemical used to identify and remove substances that trigger an allergic response.
Histamine antagonists or antihistamines are drugs that relieve allergy symptoms.<br><br>Histamine is a chemical used to identify and remove substances that trigger an allergic response.  There are four histamine receptors &#40;designated H<sub>1</sub>, H<sub>2</sub>, H<sub>3</sub>, H<sub>4</sub>&#41;. When histamine activates H<sub>1</sub> receptors, symptoms such as rashes, itching, watery eyes and trouble breathing may begin. <br><br>Antihistamines prevent histamine from stimulating the H<sub>1</sub> receptors located in the eyes, nose and throat to relieve swelling and stop leaking fluid.  First generation antihistamines were non-selective for H<sub>1</sub> receptors and crossed into the brain resulting in drowsiness.  Newer antihistamines are more selective, reducing this side effect.
Watch a Video Showing How This Drug Works

Frequently Asked Questions (FAQs) on Diphenhydramine: Oral capsule

What is this medicine?

DIPHENHYDRAMINE (dye fen HYE dra meen) is an antihistamine. It is used to treat the symptoms of an allergic reaction. It is also used to treat Parkinson's disease. This medicine is also used to prevent and to treat motion sickness and as a nighttime sleep aid.


What should I tell my health care provider before I take this medicine?

How should I use this medicine?

What if I miss a dose?

What may interact with this medicine?

What should I watch for while using this medicine?

What side effects may I notice from receiving this medicine?

Where should I keep my medicine?

Drugs Related by Class to Diphenhydramine: Oral capsule
Previous Class name
Class Name : First generation (sedating) Antihistamines

Related Brand Name Drugs :

AHIST: Oral tablet  |  Aldex AN: Chewable tablet  |  Alka-Seltzer Plus Allergy: Oral tablet  |  Aller-Chlor: Oral tablet  |  Arbinoxa: Oral solution  |  Arbinoxa: Oral tablet  |  Atarax: Oral solution  |  Atarax: Oral tablet  |  Benadryl Allergy Children's: Oral solution  |  Benadryl Allergy Dye Free: Oral capsule  |  Benadryl Allergy Dye Free: Oral capsule, liquid filled  |  Benadryl Allergy Kapgel: Oral tablet  |  Benadryl Allergy Ultratab: Oral tablet  |  Benadryl Allergy: Oral capsule  |  Benadryl Allergy: Oral solution  |  Benadryl Children's Allergy Fastmelt: Oral disintegrating tablet  |  Benadryl Children's Allergy: Chewable tablet  |  Benadryl Children's Allergy: Oral solution  |  Benadryl Children's Perfect Measure: Oral solution  |  Benadryl: Solution for injection  |  Benadryl: Topical cream  |  Benadryl: Topical solution  |  Benadryl: Topical spray, solution  |  BroveX CT: Chewable tablet  |  Chlor-Trimeton Allergy 12 Hour: Oral tablet, extended release 12 hour  |  Chlor-Trimeton Allergy: Oral tablet  |  Chlor-Trimeton: Oral tablet  |  Chlorphen SR: Oral tablet, extended release 12 hour  |  Doxytex: Oral solution  |  ElixSure Allergy: Oral solution  |  Histex PD: Oral solution  |  Lodrane: Oral capsule  |  Lodrane: Oral tablet, extended release  |  Nytol: Oral capsule, liquid filled  |  Nytol: Oral tablet  |  Palgic: Oral solution  |  Palgic: Oral tablet  |  PediaCare Children's Allergy: Oral solution  |  PediaCare Nighttime Cough: Oral solution  |  Pediox: Oral solution  |  Periactin: Oral tablet  |  Respa-BR: Oral tablet, extended release  |  RyVent: Oral tablet  |  Tavist Allergy: Oral tablet  |  Unisom: Oral capsule, liquid filled  |  Unisom: Oral tablet  |  VANAHIST PD: Oral solution  |  VanaClear PD: Oral solution  |  Vistaril: Oral capsule  |  Vistaril: Oral suspension  |  Vistaril: Solution for injection
Most Commonly Used Drugs by Class

Related Generic Drugs :

Next Class name
CVS Pharmacy Patient Statistics for Diphenhydramine: Oral capsule
Usage by Gender
63.74%
36.26%
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage by Age
13.35%
22.22%
39.85%
24.58%
In-Depth Information on This Drug
Select a specific strength to visit the detail page where you'll find :
  • Reported side effects
  • Daily life interactions
Select a Strength
Patient Experiences with Diphenhydramine

Be the first to share your experience!

We want to help our customers stay educated about the medications they are taking. Submit
your own observations and experiences to benefit others.

Average Scores
Easy to Take:
Works as Intended:
Tolerable: