Diphenhydramine Oral Capsule 25Mg Drug Medication Dosage Information
show timeout overlay link

Your Session Is About to Expire

This online session is about to expire due to inactivity. Click Continue to return to page.

  • Weekly Ad

Diphenhydramine: Oral capsule (25mg)

Also see:
  • Get answers to Frequently Asked Questions (FAQs)
  • Find other class related drugs
  • Find additional patient usage statistics

Visit Drug Summary Page
Drug Image file DrugItem_11886.JPG
Diphenhydramine 25mg Cap
Eon Labs Inc a Division of Sandoz
Pill Identification: E648 E648 
Drug Image file default-drug-image.png
Diphenhydramine 25mg Cap
Drug Image file default-drug-image.png
Diphenhydramine 25mg Cap
Drug Image file default-drug-image.png
Diphenhydramine 25mg Cap
Drug Image file default-drug-image.png
Diphenhist 25mg Cap

What is this Medicine?

DIPHENHYDRAMINE (dye fen HYE dra meen) is an antihistamine. It is used to treat the symptoms of an allergic reaction. It is also used to treat Parkinson's disease. This medicine is also used to prevent and to treat motion sickness and as a nighttime sleep aid.

CVS Pharmacy Patient Statistics for Diphenhydramine: Oral capsule(25mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
Select a Medication

Diphenhydramine Hydrochloride 25mg Capsule

NDC: 001850648
  • Over the Counter
    (Prescription Not Required)
  • Not a Controlled Drug
    (CSA Schedule)




Labeled but not FDA approved for the following conditions:
Pruritus, Cough, Urticaria, Allergic Rhinitis, Parkinson's Disease, Vertigo, Parkinsonism, Motion Sickness, Sneezing, Rhinorrhea, Common Cold, Insomnia

Storage Information
Store at room temperature (between 59 to 86 degrees F)
Diphenhydramine Hydrochloride 25mg Capsule
Drug Image file DrugItem_11886.JPG
Eon Labs Inc a Division of Sandoz
Pill Identification: E648 E648 
Shape: capsule
Color: pink,white

Reported Side Effects for Diphenhydramine Hydrochloride 25mg Capsule

Restlessness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
2.5%*
Severity: MILD
Onset: EARLY
Headache Incidence:
2.5%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
4.4%*
Severity: MILD
Onset: DELAYED
Dry Mouth Incidence:
>4.9%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
21.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Diphenhydramine Hydrochloride 25mg Capsule

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Diphenhydramine Hydrochloride 25mg Capsule(Diphenhydramine Hydrochloride)
Alcohol and CNS Depressants(Diphenhydramine Hydrochloride)
Avoid alcohol-containing drinks while taking this medicine. Using this drug along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how this drug affects you, and especially if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Pregnancy & Lactation Information
Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


Learning More About
Visit the Drug Summary page where you can:
  • Get answers to Frequently Asked Questions (FAQs)
  • Find other class related drugs
  • Find additional patient usage statistics
Learn More
Patient Experiences with Diphenhydramine

Be the first to share your experience!

We want to help our customers stay educated about the medications they are taking. Submit your own observations and experiences to benefit others.

Average Scores
Easy to Take 
0 / 5
0 / 5
Works as Intended 
0 / 5
0 / 5
Tolerable 
0 / 5
0 / 5