Dutoprol Oral Tablet, Extended Release 100-12.5Mg Drug Medication Dosage Information
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DUTOPROL: Oral tablet, extended release (100-12.5mg)

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DUTOPROL 100-12.5mg ER Tab

What is this Medicine?

METOPROLOL; HYDROCHLOROTHIAZIDE (me TOE proe lole; hye droe klor oh THYE a zide) is a combination of a beta-blocker and a diuretic. It is used to treat high blood pressure.

CVS Pharmacy Patient Statistics for DUTOPROL: Oral tablet, extended release(100-12.5mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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DUTOPROL 100mg-12.5mg Extended-Release Tablet

NDC: 003101097
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Hypertension

Storage Information
Store at 77 degrees F; excursions permitted to 59-86 degrees F
DUTOPROL 100mg-12.5mg Extended-Release Tablet

Reported Side Effects for DUTOPROL 100mg-12.5mg Extended-Release Tablet

Elevated Hepatic Enzymes Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Breathing Difficulties Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Yellow Skin Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Wheezing Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Gas Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Low Potassium Levels Incidence:
<10.0%*
Severity: MODERATE
Onset: DELAYED
Heartburn Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Ear Pain Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Swelling Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Appetite Incidence:
1.0%*
Severity: MILD
Onset: DELAYED
Shortness Of Breath Incidence:
1.0%*
Severity: MODERATE
Onset: EARLY
Bruises Incidence:
1.0%*
Severity: MILD
Onset: DELAYED
Loose Stools Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Ringing In Ears Incidence:
1.0%*
Severity: MILD
Onset: DELAYED
Dry Mouth Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Loss Of Memory Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Blurred Vision Incidence:
1.0%*
Severity: MODERATE
Onset: EARLY
Confusion Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Impotence (erectile Dysfunction) Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Gout Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Muscle And/Or Bone Pain Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Nightmares Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
5.0%*
Severity: MODERATE
Onset: DELAYED
Slow Heart Beat Incidence:
6.0%*
Severity: SEVERE
Onset: RAPID
Lightheadedness Incidence:
10.0%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
10.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
10.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
10.0%*
Severity: MILD
Onset: EARLY
Flu Incidence:
10.0%*
Severity: MILD
Onset: DELAYED
Balance Problems Incidence:
10.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for DUTOPROL 100mg-12.5mg Extended-Release Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Marijuana and DUTOPROL 100mg-12.5mg Extended-Release Tablet(Metoprolol Succinate)
Marijuana and Beta-blockers(Metoprolol Succinate)
Do not take Marijuana, Medical and Beta-Blockers (examples: Coreg, Metoprolol or Lopressor or Toprol, Nadolol or Corgard, Propranolol or Inderal) together without talking to your health care provider. Marijuana, Medical may decrease the effectiveness of Beta-Blockers. It is possible that Marijuana, Medical can cause high blood pressure, increased heart rate or other heart-related side effects in persons predisposed to these conditions, which may make the Beta-Blocker-type drug less effective at treating heart or blood pressure related problems.
Moderate Lifestyle Interaction
Alcohol and DUTOPROL 100mg-12.5mg Extended-Release Tablet(Hydrochlorothiazide)
Alcohol and Antihypertensives(Hydrochlorothiazide)
Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Compatible - This drug is generally safe to take by nursing mothers.


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