Eplerenone Oral Tablet 25Mg Drug Medication Dosage Information
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Eplerenone: Oral tablet (25mg)

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Drug Image file DrugItem_13570.JPG
Eplerenone 25mg Tab
Greenstone Ltd
Pill Identification: G  |  25mg
Drug Image file DrugItem_19679.JPG
Eplerenone 25mg Tab
Sandoz Inc
Pill Identification: SZ  |  12

What is this Medicine?

EPLERENONE (e PLER en one) is used to treat high blood pressure. This medicine is also used to improve symptoms of heart failure.

CVS Pharmacy Patient Statistics for Eplerenone: Oral tablet(25mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Eplerenone 25mg Tablet

NDC: 597621710
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Acute Myocardial Infarction, Hypertension, Heart Failure, Reduction Of Cardiovascular Mortality

Storage Information
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Eplerenone 25mg Tablet
Drug Image file DrugItem_13570.JPG
Greenstone Ltd
Pill Identification: G  |  25mg
Shape: diamond
Color: yellow

Reported Side Effects for Eplerenone 25mg Tablet

Elevated Hepatic Enzymes Incidence:
<0.7%*
Severity: MODERATE
Onset: DELAYED
High Triglycerides Incidence:
<15.0%*
Severity: MODERATE
Onset: DELAYED
High Cholesterol Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Breast Pain Incidence:
0.3-1.3%*
Severity: MILD
Onset: DELAYED
High Uric Acid Level Incidence:
0.3%*
Severity: MODERATE
Onset: DELAYED
Gynecomastia Incidence:
0.5-1.0%*
Severity: MILD
Onset: DELAYED
Vaginal Bleeding Incidence:
0.6-2.1%*
Severity: MODERATE
Onset: DELAYED
Stomach Pain Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
2.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
2.0%*
Severity: MILD
Onset: EARLY
Cough Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Low Blood Sodium Levels Incidence:
2.3%*
Severity: MODERATE
Onset: DELAYED
Lightheadedness Incidence:
3.0%*
Severity: MILD
Onset: EARLY
High Potassium Level Incidence:
3.4%*
Severity: SEVERE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Eplerenone 25mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Grapefruit juice and Eplerenone 25mg Tablet(Eplerenone)
Grapefruit juice and Eplerenone(Eplerenone)
An interaction between Eplerenone and Grapefruit juice is possible, but they may be used together. If you drink Grapefruit juice regularly, do not change how often or how much grapefruit juice you drink. Grapefruit juice may change the amount of Eplerenone in the blood. This might cause side effects like high potassium levels in the blood. When the potassium level is too high, this can cause muscle weakness, or an abnormal heart rhythm. If you experience extreme muscle weakness, chest pain, pounding heartbeat, or an unusually fast or slow heart beat, contact your health care provider immediately. While taking these drugs together, your prescriber may order a blood test to check the amount of potassium in your blood. DO NOT take potassium supplements of any type unless they are prescribed for you by your health care provider. Discuss any other medicines or dietary supplements that you are taking with your health care provider.
Moderate Lifestyle Interaction
Alcohol and Eplerenone 25mg Tablet(Eplerenone)
Alcohol and Antihypertensives(Eplerenone)
Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Pregnancy & Lactation Information
FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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