Gleevec Oral Tablet 100Mg Drug Medication Dosage Information
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Gleevec: Oral tablet (100mg)

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Drug Image file DrugItem_2223.JPG
Gleevec 100mg Tab
Novartis Pharmaceuticals Corp
Pill Identification: S A  |  NVR

What is this Medicine?

IMATINIB (i MAT in ib) is a chemotherapy drug. It targets a specific protein within cancer cells and stops the cancer cells from growing. It is used to treat certain leukemias, myelodysplastic syndromes, and other cancers. It is also used to treat specific digestive tract tumors called GISTs.

CVS Pharmacy Patient Statistics for Gleevec: Oral tablet(100mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information

Gleevec 100mg Tablet

NDC: 000780401
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Dermatofibrosarcoma Protuberans, Hypereosinophilic Syndrome, Systemic Mastocytosis, Myelodysplastic Syndrome (MDS), Acute Lymphocytic Leukemia (ALL), Chronic Eosinophilic Leukemia (CEL), Gastrointestinal Stromal Tumors (GIST), Chronic Myelogenous Leukemia (CML)

Sometimes used for but not FDA approved for the following conditions:
Desmoid Tumor

Storage Information
Protect from moisture
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Gleevec 100mg Tablet
Drug Image file DrugItem_2223.JPG
Novartis Pharmaceuticals Corp
Pill Identification: S A  |  NVR
Shape: round
Color: yellow-orange

Reported Side Effects for Gleevec 100mg Tablet

Lightheadedness Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Stevens-Johnson Syndrome Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Liver Failure Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
High Pressure In Lungs Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Pulmonary Fibrosis Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Death Of Liver Tissue Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Hypoxia Incidence:
<9.0%*
Severity: SEVERE
Onset: EARLY
Itching Incidence:
<5.4%*
Severity: SEVERE
Onset: RAPID
Lung Inflammation Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Sore Throat Incidence:
<5.4%*
Severity: SEVERE
Onset: DELAYED
Inflamed Optic Nerve Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Tiredness Incidence:
<13.1%*
Severity: SEVERE
Onset: EARLY
Muscle Pain Incidence:
<5.6%*
Severity: SEVERE
Onset: EARLY
Inability To Sleep Incidence:
<0.9%*
Severity: SEVERE
Onset: EARLY
Bowel Obstruction Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Feeling Sick Incidence:
<13.1%*
Severity: SEVERE
Onset: EARLY
Low Phosphate Level Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Nail Discoloration Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Low Calcium Levels Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Fluid Retention Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Heart Attack Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Inflamed Blood Vessels Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Abnormal Heart Rhythm Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Weakness Incidence:
<13.1%*
Severity: SEVERE
Onset: DELAYED
Flu Incidence:
<0.8%*
Severity: SEVERE
Onset: DELAYED
Infection Incidence:
<8.0%*
Severity: SEVERE
Onset: DELAYED
Low Albumin In Blood Incidence:
<4.0%*
Severity: SEVERE
Onset: DELAYED
Increased Blood Sugar Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Blurred Vision Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Fluid Around The Heart Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Bleeding Incidence:
<19.0%*
Severity: SEVERE
Onset: EARLY
Chills Incidence:
<4.6%*
Severity: SEVERE
Onset: RAPID
Dry Skin Incidence:
<0.5%*
Severity: SEVERE
Onset: DELAYED
Confusion Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Swelling Incidence:
<13.1%*
Severity: SEVERE
Onset: DELAYED
Upset Stomach Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Vesicular Rash Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Depression Incidence:
<0.8%*
Severity: SEVERE
Onset: DELAYED
Weight Gain Incidence:
<7.0%*
Severity: SEVERE
Onset: DELAYED
Cough Incidence:
<4.5%*
Severity: SEVERE
Onset: DELAYED
Red, Pimple Rash Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Inflamed Colon Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Swelling Of The Brain Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Suddenly Stopped Heart Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Irregular Heart Beat Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Joint Pain Incidence:
<6.0%*
Severity: SEVERE
Onset: DELAYED
Aplastic Anemia Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Nervousness Incidence:
<0.8%*
Severity: SEVERE
Onset: DELAYED
Decreased Appetite Incidence:
<6.6%*
Severity: SEVERE
Onset: DELAYED
Angioedema Incidence:
<0.1%*
Severity: SEVERE
Onset: RAPID
Chest Pain Incidence:
<0.1%*
Severity: MODERATE
Onset: EARLY
Hair Loss Incidence:
<4.3%*
Severity: SEVERE
Onset: DELAYED
High Blood Pressure Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Headache Incidence:
<5.7%*
Severity: SEVERE
Onset: EARLY
Paresthesias Incidence:
<0.5%*
Severity: SEVERE
Onset: DELAYED
Hemolytic Anemia Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
High Bilirubin Level Incidence:
<4.0%*
Severity: SEVERE
Onset: DELAYED
Fever Incidence:
<8.0%*
Severity: SEVERE
Onset: EARLY
Stomach Ulcer Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Decreased Sexual Desire Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Enlarged Lymph Nodes Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Macular Edema Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Mouth Sores Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Causing To Be Hungry Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Eye Irritation Incidence:
0.1-1.0%*
Severity: MILD
Onset: RAPID
Melena Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Heavy Menstrual Period Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Decreased Memory Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Fainting Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Bleeding Within The Eye Incidence:
0.1-10.0%*
Severity: SEVERE
Onset: DELAYED
Testicular Swelling Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Bruise Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Vomiting Of Blood Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Brain Bruise Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Deafness Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Gynecomastia Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Darkened Skin Patches Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Belching Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Bruise Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: RAPID
Bleeding In Eye Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Impotence (erectile Dysfunction) Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Kidney Failure Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Red Spotted Rash Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Increased Urination Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Inflammation Of The Lip Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Blistery Rash Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Increase In Breast Size Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Shaking Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Erythema Multiforme Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Ringing In Ears Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Throat Inflammation Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Unusual Skin Lightening Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Restless Legs Syndrome (RLS) Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Fluid In Lungs Incidence:
0.1-6.9%*
Severity: SEVERE
Onset: EARLY
Exfoliative Dermatitis Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Psoriasis Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Around The Lungs Incidence:
0.1-6.9%*
Severity: SEVERE
Onset: DELAYED
Eye Pain Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Inflamed Hair Follicles Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Migraine Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
High Pressure In Brain Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Low Blood Pressure Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: RAPID
Low Blood Sodium Levels Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Low Magnesium Levels Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
High Uric Acid Level Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
High Potassium Level Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Excessive Sweating Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
High Calcium Levels Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Gout Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Extra Abdominal Fluid Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Optic Disc Swelling Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Pancreas Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Irregular Periods Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Yellow Skin Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Liver Infection Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Blood In The Urine Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Difficulty Swallowing Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Cataracts Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Hives Incidence:
0.1-1.0%*
Severity: MILD
Onset: RAPID
Balance Problems Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Dehydration Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Eyes Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
0.2-8.0%*
Severity: SEVERE
Onset: DELAYED
Bleeding In The Brain Incidence:
0.2-9.0%*
Severity: SEVERE
Onset: DELAYED
Gas Incidence:
0.2-1.0%*
Severity: SEVERE
Onset: EARLY
Sinus Infection Incidence:
0.2-0.4%*
Severity: SEVERE
Onset: DELAYED
Night Sweats Incidence:
0.2-1.0%*
Severity: SEVERE
Onset: EARLY
Stomach Pain Incidence:
0.3-13.8%*
Severity: SEVERE
Onset: EARLY
Low White Blood Cell Counts Incidence:
0.3-1.6%*
Severity: SEVERE
Onset: DELAYED
Chest Pain Incidence:
0.4-2.0%*
Severity: SEVERE
Onset: EARLY
Muscle Cramps Incidence:
0.4-2.2%*
Severity: SEVERE
Onset: DELAYED
Constipation Incidence:
0.4-5.1%*
Severity: SEVERE
Onset: DELAYED
Loose Stools Incidence:
0.5-9.0%*
Severity: SEVERE
Onset: EARLY
Vomiting Incidence:
0.5-9.2%*
Severity: SEVERE
Onset: EARLY
Upset Stomach Incidence:
0.5-9.0%*
Severity: SEVERE
Onset: EARLY
Shortness Of Breath Incidence:
0.5-7.0%*
Severity: SEVERE
Onset: EARLY
Tired Incidence:
0.5-13.1%*
Severity: SEVERE
Onset: EARLY
Mouth Ulcers Incidence:
0.6-5.4%*
Severity: SEVERE
Onset: DELAYED
Back Pain Incidence:
0.6-1.0%*
Severity: SEVERE
Onset: DELAYED
Low Lymphocytes Incidence:
0.7-1.9%*
Severity: SEVERE
Onset: DELAYED
Heart Failure Incidence:
0.7-1.1%*
Severity: SEVERE
Onset: DELAYED
Low Potassium Levels Incidence:
0.8-4.0%*
Severity: SEVERE
Onset: DELAYED
Skin Rash Incidence:
0.9-8.9%*
Severity: SEVERE
Onset: EARLY
Weakness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Bruises Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Photosensitivity Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Nose Bleed Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Dry Eyes Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Conjunctivitis Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Eosinophilia Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Skin Redness Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Dry Mouth Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Flushing Incidence:
1.0-10.0%*
Severity: MILD
Onset: RAPID
Heartburn Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Low Platelet Count Incidence:
1.0-63.0%*
Severity: SEVERE
Onset: DELAYED
High Amylase Levels Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Around The Heart Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Increased Body Fluid Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Nerve Pain Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Rapid Heart Rate Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Pancytopenia Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Stomach Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Intestinal Bleeding Incidence:
1.4-8.0%*
Severity: SEVERE
Onset: DELAYED
Bone Pain Incidence:
1.6%*
Severity: SEVERE
Onset: DELAYED
Muscle And/Or Bone Pain Incidence:
2.0-9.0%*
Severity: SEVERE
Onset: EARLY
Fluid Retention Incidence:
2.5-13.1%*
Severity: SEVERE
Onset: DELAYED
Anemia Incidence:
3.0-53.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cells Incidence:
3.1-64.0%*
Severity: SEVERE
Onset: DELAYED
Metallic Taste Incidence:
6.5-12.6%*
Severity: MILD
Onset: EARLY
Secretion Of Tears Incidence:
9.8-25.0%*
Severity: MILD
Onset: EARLY
Weight Loss Incidence:
10.1%*
Severity: MILD
Onset: DELAYED
Rhinitis Incidence:
16.7%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Gleevec 100mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Grapefruit juice and Gleevec 100mg Tablet(Imatinib Mesylate)
Grapefruit juice and Imatinib Mesylate(Imatinib Mesylate)
Do not take Imatinib, STI-571 with grapefruit or grapefruit juice. Taking Imatinib with grapefruit or grapefruit juice may increase side effects of Imatinib. If you accidentally take Imatinib with grapefruit or grapefruit juice, immediately tell your doctor about any unusual effects.
Moderate Lifestyle Interaction
Marijuana and Gleevec 100mg Tablet(Imatinib Mesylate)
Marijuana and Imatinib Mesylate(Imatinib Mesylate)
Imatinib, STI-571 can theoretically decrease the elimination of Marijuana, Medical from the body. Side effects from Marijuana, Medical may get worse if you take Imatinib, STI-571. You may feel drowsy or more tired. Do not drive or operate machinery until you know how these drugs affect you. Contact your health care provider immediately if you notice slurred speech, confusion, increases heart rate, or palpitations while taking Marijuana, Medical.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
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Patient Experiences with Gleevec

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