Indomethacin Lyophilisate For Solution For Injection 1Mg Drug Medication Dosage Information
show timeout overlay link

Your Session Is About to Expire

This online session is about to expire due to inactivity. Click Continue to return to page.

  • myWeekly Ad

Indomethacin: Lyophilisate for solution for injection (1mg)

Also see:
  • Get answers to Frequently Asked Questions (FAQs)
  • Find other class related drugs
  • Find additional patient usage statistics

Visit Drug Summary Page
Drug Image file default-drug-image.png


What is this Medicine?

INDOMETHACIN (in doe METH a sin) injection is a nonsteroidal antiinflammatory drug (NSAID). It is used to close a heart defect called patent ductus arteriosus (PDA) in a baby who was born early.

In-Depth Information
Select a Medication

Indomethacin 1mg Powder for Injection (PREMIER ProRx)

NDC: 633230659
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Patent Ductus Arteriosus (PDA)

Storage Information
Protect from light
Discard unused portion. Do not store for later use.
Store in carton until contents are used
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Indomethacin 1mg Powder for Injection (PREMIER ProRx)

Reported Side Effects for Indomethacin 1mg Powder for Injection (PREMIER ProRx)

Confusion Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Blurred Vision Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Low Kidney Function Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Decreased Breathing Incidence:
<3.0%*
Severity: SEVERE
Onset: DELAYED
Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Vaginal Bleeding Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Moschcowitz Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Fainting Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Convulsions Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Nerve Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Infection Incidence:
<3.0%*
Severity: MILD
Onset: DELAYED
Increased Blood Sugar Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Blood In The Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Hole In Intestines Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Intestinal Bleeding Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Weight Gain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Lyell'S Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Kidney Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Skin Rash Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Red Spotted Rash Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Stomach Ulcer Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Muscle Weakness Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Kidney Inflammation Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Deafness Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Glycosuria Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Flushing Incidence:
<2.0%*
Severity: MILD
Onset: RAPID
Fluid Retention Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Rash Of Red Skin Bumps Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Bruise Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Dysarthria Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Corneal Deposits Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
High Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
High Potassium Level Incidence:
<9.0%*
Severity: SEVERE
Onset: DELAYED
Excessive Sweating Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Hemolytic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Heart Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Severe Allergy Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Anemia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Gas Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Fever Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Exfoliative Dermatitis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Erythema Multiforme Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Nose Bleed Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Inflamed Intestine Incidence:
<3.0%*
Severity: SEVERE
Onset: DELAYED
Drowsiness Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Disseminated Intravascular Coagulation (DIC) Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Coma Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Aplastic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Nervousness Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Decreased Appetite Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Angioedema Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
No White Blood Cells Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Mouth Ulcers Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Stevens-Johnson Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
High Pressure In Lungs Incidence:
<3.0%*
Severity: SEVERE
Onset: DELAYED
Itching Incidence:
<4.0%*
Severity: MILD
Onset: RAPID
Protein In The Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low Blood Sugar Incidence:
<3.0%*
Severity: MODERATE
Onset: EARLY
Rectal Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Hair Loss Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Nephrotic Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Inability To Sleep Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Bowel Obstruction Incidence:
<3.0%*
Severity: SEVERE
Onset: DELAYED
Low Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Stomach Pain Incidence:
1.0-3.0%*
Severity: MILD
Onset: EARLY
Balance Problems Incidence:
1.0-3.0%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
1.0-6.0%*
Severity: MODERATE
Onset: DELAYED
Depression Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
1.0-3.0%*
Severity: MILD
Onset: EARLY
Ringing In Ears Incidence:
1.0-3.0%*
Severity: MILD
Onset: DELAYED
Feeling Sick Incidence:
1.0-3.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
1.0-9.0%*
Severity: MILD
Onset: EARLY
Inflamed Stomach Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: DELAYED
Tired Incidence:
1.0-3.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
3.0-34.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
3.0-15.0%*
Severity: MILD
Onset: EARLY
Low Blood Sodium Levels Incidence:
3.0-9.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
3.0-12.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
11.0-16.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Indomethacin 1mg Powder for Injection (PREMIER ProRx)

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Indomethacin 1mg Powder for Injection (PREMIER ProRx)(Indomethacin Sodium)
Alcohol and Nonsteroidal antiinflammatory drugs (systemic)(Indomethacin Sodium)
Side effects from this drug may get worse if you drink alcohol-containing drinks. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. It is best to limit or avoid alcohol containing drinks while taking this drug, even with short term use. Many non-prescription products for headaches, pain, arthritis, or sinus pain contain drugs that may cause stomach problems along with alcohol; closely read labels before taking any medicines with alcohol-containing drinks.
Moderate Lifestyle Interaction
Tobacco and Indomethacin 1mg Powder for Injection (PREMIER ProRx)(Indomethacin Sodium)
Tobacco and Nonsteroidal antiinflammatory drugs (systemic)(Indomethacin Sodium)
Side effects from Nonsteroidal anti-inflammatory drugs may get worse if you use tobacco-containing products such as cigarettes. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. Many non-prescription products contain NSAIDs; closely read labels before taking any medicines. Eye or Skin products containing NSAIDs should not interact with tobacco.
Moderate Lifestyle Interaction
Marijuana and Indomethacin 1mg Powder for Injection (PREMIER ProRx)(Indomethacin Sodium)
Marijuana and Nonsteroidal antiinflammatory drugs (systemic)(Indomethacin Sodium)
Although an interaction is possible, these drugs may be used together. In therory, the actions of Marijuana, Medical may be decreased if you take Nonsteroidal Antiinflammatory Drugs (NSAIDs). However, the importance of this interaction is not known. Patients receiving this drug combination may notice decreased euphoria and heart rate.
Pregnancy & Lactation Information
Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
Visit the Drug Summary page where you can:
  • Get answers to Frequently Asked Questions (FAQs)
  • Find other class related drugs
  • Find additional patient usage statistics
Learn More
Patient Experiences with Indomethacin

We want to help you stay educated about the medications you are taking. View other
patient's observations and share your own.

Be sure to consult your health care provider before taking any medications. Other
patient's comments should not be considered medical advice or health care provider
recommendations.