Ixempra Lyophilisate For Solution For Injection 15Mg Drug Medication Dosage Information
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Ixempra: Lyophilisate for solution for injection (15mg)

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What is this Medicine?

IXABEPILONE (IX ab EP i lone) is a chemotherapy drug. It is used to treat advanced breast cancer.

In-Depth Information
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Ixempra 15mg Powder for Injection

NDC: 700201910
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Breast Cancer

Storage Information
Store in original package until time of use
Protect from light
Discard unused portion. Do not store for later use.
Discard reconstituted product if not used within 6 hours
Store between 36 to 46 degrees F
Ixempra 15mg Powder for Injection

Reported Side Effects for Ixempra 15mg Powder for Injection

Itching Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Paresthesias Incidence:
<21.0%*
Severity: SEVERE
Onset: DELAYED
Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Lightheadedness Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Dysesthesia Incidence:
<21.0%*
Severity: SEVERE
Onset: DELAYED
Decreased Reflexes Incidence:
<21.0%*
Severity: SEVERE
Onset: DELAYED
Heartburn Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hyperesthesia Incidence:
<21.0%*
Severity: SEVERE
Onset: DELAYED
Hypoesthesia Incidence:
<21.0%*
Severity: SEVERE
Onset: DELAYED
Hair Loss Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Constipation Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Swelling Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Headache Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Inflamed Nerve Incidence:
<21.0%*
Severity: SEVERE
Onset: DELAYED
Inability To Sleep Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Skin Rash Incidence:
1.0-2.0%*
Severity: SEVERE
Onset: EARLY
Dehydration Incidence:
1.0-2.0%*
Severity: SEVERE
Onset: DELAYED
Chest Pain Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Loose Stools Incidence:
1.0-6.0%*
Severity: SEVERE
Onset: EARLY
Shortness Of Breath Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Vomiting Incidence:
1.0-4.0%*
Severity: SEVERE
Onset: EARLY
Fever Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Muscle And/Or Bone Pain Incidence:
2.0-3.0%*
Severity: SEVERE
Onset: EARLY
Hand And Foot Syndrome Incidence:
2.0-18.0%*
Severity: SEVERE
Onset: DELAYED
Darkened Skin Patches Incidence:
2.0-11.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
2.0-3.0%*
Severity: SEVERE
Onset: EARLY
Decreased Appetite Incidence:
2.0-3.0%*
Severity: SEVERE
Onset: DELAYED
Stomach Pain Incidence:
2.0%*
Severity: SEVERE
Onset: EARLY
Cough Incidence:
2.0-6.0%*
Severity: MILD
Onset: DELAYED
Secretion Of Tears Incidence:
4.0-5.0%*
Severity: MILD
Onset: EARLY
Infection Incidence:
4.0-6.0%*
Severity: MILD
Onset: DELAYED
Mouth Ulcers Incidence:
4.0-6.0%*
Severity: SEVERE
Onset: DELAYED
Hot Flashes Incidence:
5.0-6.0%*
Severity: MODERATE
Onset: EARLY
Metallic Taste Incidence:
6.0-12.0%*
Severity: MILD
Onset: EARLY
Weight Loss Incidence:
6.0-11.0%*
Severity: MILD
Onset: DELAYED
Low Platelet Count Incidence:
7.0-8.0%*
Severity: SEVERE
Onset: DELAYED
Anemia Incidence:
8.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Joint Pain Incidence:
8.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Pain Incidence:
8.0%*
Severity: SEVERE
Onset: EARLY
Tired Incidence:
13.0-16.0%*
Severity: SEVERE
Onset: EARLY
Weakness Incidence:
13.0-16.0%*
Severity: SEVERE
Onset: DELAYED
Nerve Pain Incidence:
14.0-23.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
49.0-57.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cells Incidence:
54.0-68.0%*
Severity: SEVERE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Ixempra 15mg Powder for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Severe Lifestyle Interaction
Grapefruit juice and Ixempra 15mg Powder for Injection(Ixabepilone)
Grapefruit juice and Ixabepilone(Ixabepilone)
Do not take Ixabepilone with grapefruit or grapefruit juice. Taking Ixabepilone with grapefruit or grapefruit juice may increase side effects of Ixabepilone. If you accidentally take Ixabepilone with grapefruit or grapefruit juice, immediately tell your doctor about any unusual effects.
Major Lifestyle Interaction
Alcohol and Ixempra 15mg Powder for Injection(Ixabepilone)
Alcohol and Ixabepilone(Ixabepilone)
Ixabepilone contains a large amount of alcohol. Avoid Alcohol-containing products or beverages on the days you get Ixabelilone, as excessive sedation (difficulty staying alert), dizziness, or difficulty breathing may occur.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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