Janumet Oral Tablet 50-1000Mg Drug Medication Dosage Information
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Janumet: Oral tablet (50-1000mg)

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Drug Image file DrugItem_9159.JPG
Janumet 50mg-1000mg Tab
Merck Sharp & Dohme Corp., a Subsidiary of Merck & Co., Inc.
Pill Identification: 577 

What is this Medicine?

METFORMIN; SITAGLIPTIN (met FOR min; sit a GLIP tin) is a combination of 2 medicines used to treat type 2 diabetes. This medicine lowers blood sugar. Treatment is combined with a balanced diet and exercise.

CVS Pharmacy Patient Statistics for Janumet: Oral tablet(50-1000mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information

Janumet 50mg-1000mg Tablet

NDC: 000060577
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Type 2 Diabetes Mellitus

Storage Information
Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees F
Janumet 50mg-1000mg Tablet
Drug Image file DrugItem_9159.JPG
Merck Sharp & Dohme Corp., a Subsidiary of Merck & Co., Inc.
Pill Identification: 577 
Shape: oblong
Color: red

Reported Side Effects for Janumet 50mg-1000mg Tablet

Electrolyte Imbalance Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Megaloblastic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Electrolyte Imbalance Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Gas Incidence:
1.0-12.1%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
1.0-7.1%*
Severity: MILD
Onset: EARLY
Metallic Taste Incidence:
1.0-5.0%*
Severity: MILD
Onset: EARLY
Muscle Pain Incidence:
1.0-5.0%*
Severity: MILD
Onset: EARLY
Feeling Sick Incidence:
1.0-5.0%*
Severity: MILD
Onset: EARLY
Decreased Appetite Incidence:
1.0-5.0%*
Severity: MILD
Onset: DELAYED
Metallic Taste Incidence:
1.0-5.0%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
1.1%*
Severity: MILD
Onset: EARLY
Low Blood Sugar Incidence:
1.2%*
Severity: MODERATE
Onset: EARLY
Upset Stomach Incidence:
1.3%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
2.2%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
2.4%*
Severity: MILD
Onset: EARLY
Weakness Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Infection Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Sore Throat Incidence:
>5.0%*
Severity: MILD
Onset: DELAYED
Headache Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Fluid Retention Incidence:
8.3%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Janumet 50mg-1000mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Alcohol and Janumet 50mg-1000mg Tablet(Metformin Hydrochloride)
Alcohol and Metformin Hydrochloride(Metformin Hydrochloride)
Alcohol may interfere with the actions of Antidiabetic agents (Insulin or other drugs used to treat Diabetes). Alcoholic beverages can increase the risk of low blood sugar, or can cause increased blood sugar due to the calories in these beverages. Limit alcohol containing medicines and beverages if you are on Antidiabetic Agents. You should also learn how to recognize the signs of low blood sugar.
Moderate Lifestyle Interaction
Alcohol and Janumet 50mg-1000mg Tablet(Sitagliptin Phosphate)
Alcohol and Sitagliptin Phosphate(Sitagliptin Phosphate)
Ethanol may interfere with the actions of Antidiabetic agents. Alcoholic beverages can increase the risk of low blood sugar, or can cause increased blood sugar due to the calories in these beverages. Limit alcohol containing medicines and beverages if you are on Antidiabetic Agents. You should also learn how to recognize the signs of low blood sugar.
Minor Lifestyle Interaction
Tobacco and Janumet 50mg-1000mg Tablet(Metformin Hydrochloride)
Tobacco and Metformin Hydrochloride(Metformin Hydrochloride)
If you use tobacco or are trying to quit tobacco use, you may need to monitor your blood sugar more frequently. Nicotine, a component of tobacco, can increase the blood sugar. Also, if you are trying to quit smoking, as your body adjusts to not smoking, your blood sugar levels may change; the actions of Antidiabetic Agents (medicines used to treat diabetes) may be increased and this could lead to low blood sugar. Know the symptoms of low or high blood sugar and report them if they occur. Monitor your blood sugar regularly.
Minor Lifestyle Interaction
Tobacco and Janumet 50mg-1000mg Tablet(Sitagliptin Phosphate)
Tobacco and Sitagliptin Phosphate(Sitagliptin Phosphate)
If you use tobacco or are trying to quit tobacco use, you may need to monitor your blood sugar more frequently. Nicotine, a component of tobacco, can increase the blood sugar. Also, if you are trying to quit smoking, as your body adjusts to not smoking, your blood sugar levels may change; the actions of Antidiabetic Agents (medicines used to treat diabetes) may be increased and this could lead to low blood sugar. Know the symptoms of low or high blood sugar and report them if they occur. Monitor your blood sugar regularly.
Pregnancy & Lactation Information
FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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