Juvisync Oral Tablet 100-10Mg Drug Medication Dosage Information
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Juvisync: Oral tablet (100-10mg)

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What is this Medicine?

SIMVASTATIN; SITAGLIPTIN (SIM va stat in; sit a GLIP tin) is a combination of 2 medicines used in certain patients with type 2 diabetes. Sitagliptin lowers blood sugar. Simvastatin is known as a HMG-CoA reductase inhibitor or "statin". It lowers the level of cholesterol and triglycerides in the blood. This drug may also reduce the risk of heart attack, stroke, or other health problems in patients with risk factors for heart or blood vessel disease. Diet and lifestyle changes are often used with this drug.

In-Depth Information

Juvisync 100mg-10mg Tablet

NDC: 000060753
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Hyperlipoproteinemia, Hypercholesterolemia, Type 2 Diabetes Mellitus, Myocardial Infarction Prophylaxis, Hypertriglyceridemia, Stroke Prophylaxis

Storage Information
Store in a dry place
Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees F
Juvisync 100mg-10mg Tablet

Reported Side Effects for Juvisync 100mg-10mg Tablet

Breakdown Of Muscle Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Nerve Pain Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Immune-mediated Necrotizing Myopathy Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Disease Incidence:
0.1-0.6%*
Severity: MODERATE
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
0.4-2.1%*
Severity: MODERATE
Onset: DELAYED
Low Blood Sugar Incidence:
0.6-1.6%*
Severity: MODERATE
Onset: EARLY
Headache Incidence:
1.1-7.4%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
1.4-5.4%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
2.2-6.6%*
Severity: MODERATE
Onset: DELAYED
Sinus Infection Incidence:
2.3%*
Severity: MILD
Onset: DELAYED
Stomach Pain Incidence:
2.3-7.3%*
Severity: MILD
Onset: EARLY
Fluid Retention Incidence:
2.7-8.3%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Infection Incidence:
3.2-15.5%*
Severity: MILD
Onset: DELAYED
Muscle Pain Incidence:
3.7%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
4.0%*
Severity: MILD
Onset: EARLY
Balance Problems Incidence:
4.5%*
Severity: MILD
Onset: EARLY
Scaly And Itchy Rashes Incidence:
4.5%*
Severity: MODERATE
Onset: DELAYED
Inflamed Stomach Incidence:
4.9%*
Severity: MODERATE
Onset: DELAYED
Sore Throat Incidence:
5.2-11.0%*
Severity: MILD
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Juvisync 100mg-10mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Grapefruit juice and Juvisync 100mg-10mg Tablet(Simvastatin)
Grapefruit juice and Simvastatin(Simvastatin)
Simvastatin (Zocor) may be taken with or without food. Continue to follow the cholesterol-reducing diet recommended by your health care provider. It is recommended that you avoid taking Simvastatin with large amounts of grapefruit juice. Large amounts of grapefruit juice (greater than 1 quart per day) can increase the side effects of Simvastatin. Orange juice is safe to drink. Contact your prescriber immediately if you experience unexplained muscle aches, muscle pain or tenderness, general weakness or fatigue, side or back pain, or decreased urination while taking Simvastatin (Zocor).
Moderate Lifestyle Interaction
Alcohol and Juvisync 100mg-10mg Tablet(Sitagliptin Phosphate)
Alcohol and Sitagliptin Phosphate(Sitagliptin Phosphate)
Ethanol may interfere with the actions of Antidiabetic agents. Alcoholic beverages can increase the risk of low blood sugar, or can cause increased blood sugar due to the calories in these beverages. Limit alcohol containing medicines and beverages if you are on Antidiabetic Agents. You should also learn how to recognize the signs of low blood sugar.
Minor Lifestyle Interaction
Tobacco and Juvisync 100mg-10mg Tablet(Sitagliptin Phosphate)
Tobacco and Sitagliptin Phosphate(Sitagliptin Phosphate)
If you use tobacco or are trying to quit tobacco use, you may need to monitor your blood sugar more frequently. Nicotine, a component of tobacco, can increase the blood sugar. Also, if you are trying to quit smoking, as your body adjusts to not smoking, your blood sugar levels may change; the actions of Antidiabetic Agents (medicines used to treat diabetes) may be increased and this could lead to low blood sugar. Know the symptoms of low or high blood sugar and report them if they occur. Monitor your blood sugar regularly.
Pregnancy & Lactation Information
FIRST Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

SECOND Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

THIRD Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
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