Korlym Oral Tablet 300Mg Drug Medication Dosage Information
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Korlym: Oral tablet (300mg)

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What is this Medicine?

MIFEPRISTONE (mi FE pri stone) is a hormone-like drug. It is used in combination with other medicines to end an early pregnancy (usually during the first 7 weeks). This medicine is only available in a doctor's office, health clinic, or hospital.

Similar Brand Name Drugs : Mifeprex: Oral tablet (200mg)
In-Depth Information

Korlym 300mg Tablet

NDC: 763460073
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Cushing's Syndrome, Pregnancy Termination

Sometimes used for but not FDA approved for the following conditions:
Uterine Leiomyomata, Meningioma, Postcoital Contraception

Storage Information
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Korlym 300mg Tablet

Reported Side Effects for Korlym 300mg Tablet

Weakness Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Fainting Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
1.0-22.0%*
Severity: MILD
Onset: EARLY
Pelvic Pain Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Headache Incidence:
2.0-44.0%*
Severity: MILD
Onset: EARLY
Anemia Incidence:
2.0%*
Severity: MODERATE
Onset: DELAYED
Nervousness Incidence:
2.0-10.0%*
Severity: MILD
Onset: DELAYED
Sinus Infection Incidence:
2.0-14.0%*
Severity: MILD
Onset: DELAYED
Vaginal Discharge Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Vaginal Infection Incidence:
3.0%*
Severity: MODERATE
Onset: DELAYED
Chills Incidence:
3.0%*
Severity: MILD
Onset: RAPID
Upset Stomach Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
3.0-10.0%*
Severity: MILD
Onset: EARLY
Itching Incidence:
4.0%*
Severity: MILD
Onset: RAPID
Rash With Pustules Incidence:
4.0%*
Severity: MILD
Onset: EARLY
Fever Incidence:
4.0%*
Severity: MILD
Onset: EARLY
Feeling Sick Incidence:
5.0-10.0%*
Severity: MILD
Onset: EARLY
Back Pain Incidence:
5.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Heartburn Incidence:
5.0-10.0%*
Severity: MILD
Onset: DELAYED
Weakness Incidence:
5.0-10.0%*
Severity: MILD
Onset: EARLY
Muscle And/Or Bone Pain Incidence:
5.0-10.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
5.0-96.0%*
Severity: MILD
Onset: EARLY
Low Blood Sugar Incidence:
5.0-10.0%*
Severity: MODERATE
Onset: EARLY
Swelling Incidence:
5.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Back Pain Incidence:
9.0-16.0%*
Severity: MILD
Onset: DELAYED
Decreased Appetite Incidence:
10.0%*
Severity: MILD
Onset: DELAYED
Labor Incidence:
>10.0%*
Severity: MODERATE
Onset: EARLY
Constipation Incidence:
10.0%*
Severity: MODERATE
Onset: DELAYED
Bleeding Incidence:
>10.0%*
Severity: MODERATE
Onset: EARLY
Tired Incidence:
10.0-48.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
12.0-20.0%*
Severity: MILD
Onset: EARLY
Sore Throat Incidence:
12.0%*
Severity: MILD
Onset: DELAYED
Muscle Pain Incidence:
14.0%*
Severity: MILD
Onset: EARLY
Shortness Of Breath Incidence:
16.0%*
Severity: MODERATE
Onset: EARLY
Dry Mouth Incidence:
18.0%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
18.0-26.0%*
Severity: MILD
Onset: EARLY
High Blood Pressure Incidence:
24.0%*
Severity: MODERATE
Onset: EARLY
Fluid Retention Incidence:
26.0%*
Severity: MODERATE
Onset: DELAYED
Joint Pain Incidence:
30.0%*
Severity: MILD
Onset: DELAYED
Endometrial Hyperplasia Incidence:
38.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
43.0-61.0%*
Severity: MILD
Onset: EARLY
Low Potassium Levels Incidence:
44.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Korlym 300mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Grapefruit juice and Korlym 300mg Tablet(Mifepristone)
Grapefruit juice and Mifepristone (RU-486)(Mifepristone)
Mifepristone (also known as RU-486 or Mifeprex) does not interact with most foods. Grapefruit juice and grapefruit-containing foods may increase the effects of Mifepristone, RU-486, which may worsen side effects like abdominal pain, diarrhea, headache, or uterine cramps. Do not significantly alter your grapefruit juice intake while taking this drug.
Moderate Lifestyle Interaction
Marijuana and Korlym 300mg Tablet(Mifepristone)
Marijuana and Mifepristone (RU-486)(Mifepristone)
Mifepristone, RU-486 can theoretically decrease the elimination of Marijuana, Medical from the body. Side effects from Marijuana, Medical may worsen if you take Mifepristone, RU-486. You may feel drowsy or more tired. Do not drive or operate machinery until you know how these drugs affect you. Contact your health care provider immediately if you notice slurred speech, confusion, increases heart rate, or palpitations while taking Marijuana, Medical.
Pregnancy & Lactation Information
FIRST Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

SECOND Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

THIRD Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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