Letairis Oral Tablet 10Mg Drug Medication Dosage Information
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LETAIRIS: Oral tablet (10mg)

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What is this Medicine?

AMBRISENTAN (am bri SEN tan) is used to treat pulmonary hypertension. This medicine may help make exercise and breathing easier.

In-Depth Information

Letairis 10mg Tablet (Accredo)

NDC: 619580802
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Pulmonary Hypertension

Storage Information
Store in original container
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Letairis 10mg Tablet (Accredo)

Reported Side Effects for Letairis 10mg Tablet (Accredo)

Sinus Infection Incidence:
3.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Flushing Incidence:
4.0%*
Severity: MILD
Onset: RAPID
Stuffy Nose Incidence:
6.0-16.0%*
Severity: MILD
Onset: EARLY
Anemia Incidence:
7.0%*
Severity: MODERATE
Onset: DELAYED
Cough Incidence:
13.0%*
Severity: MILD
Onset: DELAYED
Fluid Retention Incidence:
17.0-38.0%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
34.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Letairis 10mg Tablet (Accredo)

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Alcohol and Letairis 10mg Tablet (Accredo)(Ambrisentan)
Alcohol and Antihypertensives(Ambrisentan)
Although an interaction is possible, Ethanol (alchohol) and Antihypertensive Agents (drugs used to reduce high blood pressure) may be used together. Ethanol or alchohol-containing beverages may increase the effects of Antihypertensive Agents on your blood pressure. If the blood pressure drops too low while taking Ethanol and Antihypertensive Agents, you may become dizzy or feel faint. To limit this interaction, avoid alcohol-containing beverages while taking medicines to lower your blood pressure. Do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away.
Moderate Lifestyle Interaction
Grapefruit juice and Letairis 10mg Tablet (Accredo)(Ambrisentan)
Grapefruit juice and Ambrisentan(Ambrisentan)
Although a drug interaction is possible, Ambrisentan and Grapefruite Juice may be used together. Side effects from Ambrisentan may get worse if you take Grapefruit Juice. In theory, Grapefruit Juice can decrease the elimination of Ambrisentan from the body. If your blood pressure drops too low while taking Ambrisentan, you may become dizzy or feel faint; do not stand or sit up too quickly. Contact your prescriber if you have dizziness which does not go away. While taking Ambrisentan, report promptly any signs of liver problems such as nausea, vomiting, fever, abdominal pain, jaundice, or unusual fatigue or tiredness.
Pregnancy & Lactation Information
FIRST Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

SECOND Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

THIRD Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


Learning More About
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