Leukine Lyophilisate For Solution For Injection 250Mcg Drug Medication Dosage Information
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Leukine: Lyophilisate for solution for injection (250mcg)

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What is this Medicine?

SARGRAMOSTIM, GM-CSF (sar GRAM oh stim) helps the body make more blood cells. It is used to increase the number of blood cells after chemotherapy or with a blood or bone marrow transplant.

In-Depth Information
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Leukine 250mcg Powder for Injection

NDC: 000245843
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Neutropenia, Febrile Neutropenia, Chemotherapy-induced Neutropenia, Peripheral Blood Stem Cell (PBSC) Mobilization

Sometimes used for but not FDA approved for the following conditions:
Malignant Melanoma, Ganciclovir-induced Neutropenia, Myelodysplastic Syndrome (MDS), Crohn's Disease, Zidovudine-induced Neutropenia, Aplastic Anemia

Storage Information
Refrigerate (between 36 and 46 degrees F)
Do not freeze
Leukine 250mcg Powder for Injection

Reported Side Effects for Leukine 250mcg Powder for Injection

Blood Vessel Fluid Leak Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Fluid Around The Lungs Incidence:
1.0%*
Severity: SEVERE
Onset: DELAYED
Antibody Formation Incidence:
2.3%*
Severity: MODERATE
Onset: DELAYED
Fluid Around The Heart Incidence:
4.0-25.0%*
Severity: SEVERE
Onset: DELAYED
Joint Pain Incidence:
11.0-21.0%*
Severity: MILD
Onset: DELAYED
Fluid Retention Incidence:
11.0%*
Severity: MODERATE
Onset: DELAYED
Low Blood Pressure Incidence:
13.0%*
Severity: MODERATE
Onset: RAPID
Chest Pain Incidence:
15.0%*
Severity: MODERATE
Onset: EARLY
Shortness Of Breath Incidence:
15.0-28.0%*
Severity: MODERATE
Onset: EARLY
Muscle Pain Incidence:
18.0%*
Severity: MILD
Onset: EARLY
Bone Pain Incidence:
21.0%*
Severity: MODERATE
Onset: DELAYED
Injection Site Reaction Incidence:
23.0-70.0%*
Severity: MILD
Onset: RAPID
Itching Incidence:
23.0%*
Severity: MILD
Onset: RAPID
Skin Rash Incidence:
44.0-70.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Compatible - This drug is generally safe to take by nursing mothers.


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