Lupron Depot Lyophilisate For Suspension For Injection 11.25Mg Drug Medication Dosage Information
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Lupron Depot: Lyophilisate for suspension for injection (11.25mg)

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Lupron Depot 3-Mo 11.25mg Inj

What is this Medicine?

LEUPROLIDE (loo PROE lide) is a man-made protein that acts like a natural hormone in the body. It decreases testosterone in men and decreases estrogen in women. In men, this medicine is used to treat advanced prostate cancer. In women, some forms of this medicine may be used to treat endometriosis, uterine fibroids, or other female hormone-related problems.

CVS Pharmacy Patient Statistics for Lupron Depot: Lyophilisate for suspension for injection(11.25mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information

Lupron Depot 3-Month 11.25mg Powder for Injection

NDC: 000743663
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Precocious Puberty, Uterine Leiomyomata, Prostate Cancer, Endometriosis

Sometimes used for but not FDA approved for the following conditions:
Breast Cancer, Stuttering Priapism, Benign Prostatic Hyperplasia (BPH)

Storage Information
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Lupron Depot 3-Month 11.25mg Powder for Injection

Reported Side Effects for Lupron Depot 3-Month 11.25mg Powder for Injection

Confusion Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Lightheadedness Incidence:
<8.3%*
Severity: MILD
Onset: EARLY
Metallic Taste Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Hoarseness Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Bruise Incidence:
<34.6%*
Severity: MILD
Onset: DELAYED
Emotional Lability Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Feminization Incidence:
<2.0%*
Severity: SEVERE
Onset: DELAYED
Growth Inhibition Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Coughing Up Blood Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Enlarged Liver Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Hiccups Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Hyperesthesia Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
<12.0%*
Severity: MODERATE
Onset: DELAYED
Nerve Pain Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Convulsions Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Fainting Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Loss Of Memory Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Anaphylactoid Reactions Incidence:
<0.1%*
Severity: SEVERE
Onset: RAPID
Causing To Be Hungry Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Abnormal Heart Rhythm Incidence:
<5.0%*
Severity: SEVERE
Onset: EARLY
Weakness Incidence:
<12.2%*
Severity: MILD
Onset: DELAYED
Back Pain Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Blurred Vision Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Broken Bones Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Increase In Breast Size Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Chills Incidence:
<5.0%*
Severity: MILD
Onset: RAPID
Bruises Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Skin Rash Incidence:
<3.0%*
Severity: MILD
Onset: EARLY
Blockage In The Kidney Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Darkened Skin Patches Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Skin Irritation Incidence:
<12.2%*
Severity: MILD
Onset: EARLY
Skin Ulcer Incidence:
<3.0%*
Severity: MODERATE
Onset: DELAYED
Testicular Atrophy Incidence:
<20.2%*
Severity: MODERATE
Onset: DELAYED
Blood Clot Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Visual Impairment Incidence:
<5.0%*
Severity: SEVERE
Onset: EARLY
Weight Gain Incidence:
<2.3%*
Severity: MILD
Onset: DELAYED
Weight Loss Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Decreased Memory Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Hypoxia Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Decreased Healing Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Impotence (erectile Dysfunction) Incidence:
<5.4%*
Severity: MODERATE
Onset: DELAYED
Injection Site Reaction Incidence:
<37.5%*
Severity: MILD
Onset: RAPID
Tiredness Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Enlarged Lymph Nodes Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Feeling Sick Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Muscle And/Or Bone Pain Incidence:
<32.7%*
Severity: MILD
Onset: EARLY
Nighttime Urination Incidence:
<3.8%*
Severity: MILD
Onset: EARLY
Paresthesias Incidence:
<8.2%*
Severity: MILD
Onset: DELAYED
Parosmia Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Stomach Ulcer Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Photosensitivity Incidence:
<0.1%*
Severity: MILD
Onset: DELAYED
Drooping Eyelids Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Painful Urination Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Swelling Incidence:
<20.8%*
Severity: MODERATE
Onset: DELAYED
Epididymis Inflammation Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Nose Bleed Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Erythema Multiforme Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Tired Incidence:
<17.5%*
Severity: MILD
Onset: EARLY
Fever Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Gas Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Gum Inflammation Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Enlarged Thyroid Gland Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
<10.2%*
Severity: MILD
Onset: EARLY
Heart Failure Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Excessive Sweating Incidence:
<5.3%*
Severity: MILD
Onset: DELAYED
High Blood Pressure Incidence:
<8.0%*
Severity: MODERATE
Onset: EARLY
Low Blood Pressure Incidence:
<5.0%*
Severity: MODERATE
Onset: RAPID
Inability To Sleep Incidence:
<8.5%*
Severity: MILD
Onset: EARLY
Melasma Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Muscle Pain Incidence:
<8.2%*
Severity: MILD
Onset: EARLY
Distressed Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Hair Loss Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Lazy Eye Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Anemia Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Chest Pain Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Decreased Appetite Incidence:
<6.0%*
Severity: MILD
Onset: DELAYED
Nervousness Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Joint Pain Incidence:
<9.3%*
Severity: MILD
Onset: DELAYED
Irregular Heart Beat Incidence:
<5.0%*
Severity: SEVERE
Onset: EARLY
Bladder Spasm Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Bone Pain Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Slow Heart Beat Incidence:
<5.0%*
Severity: SEVERE
Onset: RAPID
Constipation Incidence:
<9.9%*
Severity: MODERATE
Onset: DELAYED
Dehydration Incidence:
<8.2%*
Severity: MODERATE
Onset: DELAYED
Depression Incidence:
<5.3%*
Severity: MODERATE
Onset: DELAYED
Diabetes Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Menstrual Cramps Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Uncontrolled Urination Incidence:
<5.0%*
Severity: MODERATE
Onset: EARLY
Retaining Urine Incidence:
<4.6%*
Severity: MODERATE
Onset: EARLY
Urinary Urgency Incidence:
<6.0%*
Severity: MILD
Onset: EARLY
Hives Incidence:
<0.1%*
Severity: MILD
Onset: RAPID
Balance Problems Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Dry Eyes Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Dry Skin Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Dry Mouth Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Difficulty Swallowing Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Intestinal Bleeding Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Intestinal Blockage Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Blood In The Urine Incidence:
<6.0%*
Severity: MODERATE
Onset: DELAYED
Infection Incidence:
<12.2%*
Severity: MILD
Onset: DELAYED
Muscle Cramps Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Heart Attack Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Disease Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Around The Lungs Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Fluid In Lungs Incidence:
<5.0%*
Severity: SEVERE
Onset: EARLY
Blood Clot In Lung Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Pulmonary Fibrosis Incidence:
<5.0%*
Severity: SEVERE
Onset: DELAYED
Ringing In Ears Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Unusual Skin Lightening Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Cough Incidence:
1.3-6.6%*
Severity: MILD
Onset: DELAYED
Blood Clot Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Shortness Of Breath Incidence:
2.0%*
Severity: MODERATE
Onset: EARLY
Irritated Blood Vessels Incidence:
2.0%*
Severity: MODERATE
Onset: RAPID
Gynecomastia Incidence:
2.2-7.0%*
Severity: MILD
Onset: DELAYED
Increased Urination Incidence:
2.2-6.0%*
Severity: MILD
Onset: EARLY
Inflamed Colon Incidence:
2.5%*
Severity: MODERATE
Onset: DELAYED
Night Sweats Incidence:
2.7-3.3%*
Severity: MILD
Onset: EARLY
Vaginal Bleeding Incidence:
3.0%*
Severity: MODERATE
Onset: DELAYED
Vaginal Discharge Incidence:
3.0%*
Severity: MILD
Onset: DELAYED
Dandruff Incidence:
3.0%*
Severity: MILD
Onset: DELAYED
Vaginal Infection Incidence:
3.0%*
Severity: MODERATE
Onset: DELAYED
Breast Pain Incidence:
3.1-7.0%*
Severity: MILD
Onset: DELAYED
Decreased Sexual Desire Incidence:
3.3-5.4%*
Severity: MILD
Onset: DELAYED
Weakness Incidence:
3.6%*
Severity: MILD
Onset: EARLY
Testicular Pain Incidence:
3.8%*
Severity: MILD
Onset: EARLY
Eosinophilia Incidence:
>5.0%*
Severity: MODERATE
Onset: DELAYED
Increased Blood Sugar Incidence:
>5.0%*
Severity: MODERATE
Onset: DELAYED
Increased Blood Fats Incidence:
>5.0%*
Severity: MODERATE
Onset: DELAYED
High Phosphate Levels Incidence:
>5.0%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
>5.0%*
Severity: MODERATE
Onset: DELAYED
High Uric Acid Level Incidence:
>5.0%*
Severity: MODERATE
Onset: DELAYED
Belching Incidence:
>5.0%*
Severity: MILD
Onset: EARLY
Hot Flashes Incidence:
8.3-73.3%*
Severity: MODERATE
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

SECOND Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

THIRD Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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Patient Experiences with Lupron Depot

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