Marplan Oral Tablet 10Mg Drug Medication Dosage Information
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Marplan: Oral tablet (10mg)

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Marplan 10mg Tab

What is this Medicine?

ISOCARBOXAZID (eye soe kar BOX azid) is an monoamine oxidase inhibitor (MAOI). It is used to treat depression.

CVS Pharmacy Patient Statistics for Marplan: Oral tablet(10mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Marplan 10mg Tablet

NDC: 306980032
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Depression

Storage Information
Store at room temperature (between 59 to 86 degrees F)
Marplan 10mg Tablet

Reported Side Effects for Marplan 10mg Tablet

Yellow Skin Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Convulsions Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Fainting Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Restlessness Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Incoordination Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Chills Incidence:
<2.0%*
Severity: MILD
Onset: RAPID
Elated Mood Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Hallucinations Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Impotence (erectile Dysfunction) Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Increased Urination Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Rapid Muscle Twitches Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Rapid Heart Rate Incidence:
<2.0%*
Severity: MODERATE
Onset: EARLY
Paresthesias Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Photosensitivity Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Serotonin Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Spider Veins Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Distressed Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Nervousness Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Loose Stools Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
<4.0%*
Severity: MILD
Onset: EARLY
Painful Urination Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Uncontrolled Urination Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Retaining Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Memory Incidence:
2.0%*
Severity: MODERATE
Onset: DELAYED
Excessive Sweating Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Tiredness Incidence:
2.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
4.0-6.0%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
4.0-7.0%*
Severity: MODERATE
Onset: DELAYED
Shaking Incidence:
4.0%*
Severity: MILD
Onset: EARLY
Postural Low Blood Pressure Incidence:
4.0%*
Severity: MODERATE
Onset: DELAYED
Inability To Sleep Incidence:
4.0-6.0%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
6.0-9.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
6.0-15.0%*
Severity: MILD
Onset: EARLY
Weight Gain Incidence:
>10.0%*
Severity: MILD
Onset: DELAYED
Withdrawal Incidence:
>10.0%*
Severity: MODERATE
Onset: EARLY
Ejaculation Dysfunction Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Lightheadedness Incidence:
15.0-29.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Marplan 10mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Severe Lifestyle Interaction
Tyramine-containing foods and Marplan 10mg Tablet(Isocarboxazid)
Tyramine-containing foods and Monoamine oxidase inhibitors(Isocarboxazid)
Avoid foods and beverages containing tyramine while taking this medicine. The following foods can cause sudden blood pressure increases and should also be avoided: aged cheese; yeast extract; protein extract; soy sauce; fava bean or broad bean pods; smoked meats; pickled meats; smoked poultry; pickled poultry; smoked fish (lox, smoked salmon); pickled fish (pickled herring); fermented sausage (bologna, pepperoni, salami, summer sausage); bananas; avocados; any over-ripe fruit. Selegiline products have specific guidelines. Dietary and beverage restrictions should continue for at least 2 weeks after stopping this medicine.
Severe Lifestyle Interaction
Alcohol and Marplan 10mg Tablet(Isocarboxazid)
Alcohol and Monoamine oxidase inhibitors(Isocarboxazid)
Alcohol interactions with this medicine can be serious and may cause increased sedation, increased blood pressure ('hypertensive crisis') or other side effects. Ask your health care provider for a list of items to avoid. You must adhere to all dietary restrictions. Alcoholic beverages to avoid include beer; wine; sherry; hard liquor; or liqueurs. Dietary and beverage restrictions should continue for at least 2 weeks after stopping this medicine.
Severe Lifestyle Interaction
Caffeine-containing Foods/Beverages and Marplan 10mg Tablet(Isocarboxazid)
Caffeine-containing Foods/Beverages and Monoamine oxidase inhibitors(Isocarboxazid)
Do not take this medicine with caffeine-containing dietary supplements, medicines, foods or beverages without talking to your health care provider. Food, medicine, and dietary interactions can be serious. Rapid heartbeats or serious increases in blood pressure, known as "hypertensive crisis", may occur. Try to avoid or limit the intake of all items containing caffeine such as tea, coffee, chocolate, and cola. Do not take nonprescription medicines that contain Caffeine, like "stay awake" or weight loss products, including herbal diet aids. Caffeine restrictions should continue for at least 1 to 2 weeks after stopping this medicine.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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Patient Experiences with Marplan

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