Matulane Oral Capsule 50Mg Drug Medication Dosage Information
show timeout overlay link

Your Session Is About to Expire

This online session is about to expire due to inactivity. Click Continue to return to page.

  • Weekly Ad

Matulane: Oral capsule (50mg)

Also see:
  • Get answers to Frequently Asked Questions (FAQs)
  • Find other class related drugs
  • Find additional patient usage statistics

Visit Drug Summary Page
Drug Image file DrugItem_5776.JPG
Matulane 50mg Cap
Sigma-Tau Pharmaceuticals, Inc.
Pill Identification: MATULANE sigma-tau 

What is this Medicine?

PROCARBAZINE (proe KAR ba zeen) is a chemotherapy drug. This medicine reduces the growth of cancer cells. It is used to treat Hodgkin's disease. It is often given with other cancer drugs.

In-Depth Information

Matulane 50mg Capsule

NDC: 544820053
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Hodgkin's Disease

Sometimes used for but not FDA approved for the following conditions:
Medulloblastoma, Malignant Glioma, Non-Hodgkin's Lymphoma (NHL), Non-small Cell Lung Cancer (NSCLC), Stem Cell Transplant Preparation

Storage Information
Storage information not listed
Matulane 50mg Capsule
Drug Image file DrugItem_5776.JPG
Sigma-Tau Pharmaceuticals, Inc.
Pill Identification: MATULANE sigma-tau 
Shape: capsule
Color: white

Reported Side Effects for Matulane 50mg Capsule

Anemia Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Low Platelet Count Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Low White Blood Cell Counts Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Matulane 50mg Capsule

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Severe Lifestyle Interaction
Alcohol and Matulane 50mg Capsule(Procarbazine Hydrochloride)
Alcohol and Procarbazine Hydrochloride(Procarbazine Hydrochloride)
You must avoid alcoholic beverages while taking Procarbazine. Side effects from Procarbazine may get worse if you have Alcoholic beverages or take medicines containing a significant amount of alcohol. Beverages to avoid include some beers (including alcohol-free beer); wines; sherry; hard liquor; or liqueurs. Taking these beverages along with Procarbazine might increase the risk of serious high blood pressure, confusion, restlessness, or other side effects.
Major Lifestyle Interaction
Tyramine-containing foods and Matulane 50mg Capsule(Procarbazine Hydrochloride)
Tyramine-containing foods and Procarbazine Hydrochloride(Procarbazine Hydrochloride)
Certain foods might increase the risk of side effects with Procarbazine. In addition, you should probably limit your intake of aged or smoked meats (like sausages or smoked or pickled fish), aged cheeses, and caffeine containing foods like coffee, colas, teas, and chocolate while on Procarbazine. Taking these foods along with Procarbazine might increase the risk of high blood pressure, confusion, restlessness, or other side effects. Ask your dietician or health care professional for a complete listing of foods best avoided while on Procarbazine.
Major Lifestyle Interaction
Tobacco and Matulane 50mg Capsule(Procarbazine Hydrochloride)
Tobacco and Procarbazine Hydrochloride(Procarbazine Hydrochloride)
Studies suggest that Tobacco smoking may increase the risk of rare but serious lung side effects (lung cancer) from Procarbazine therapy. Talk to your prescriber about stopping Tobacco smoking if you are receiving Procarbazine treatment. Discuss any new or worsening side effects, such as a persistent, non-productive cough or shortness of breath, with your health care provider while you are receiving Procarbazine.
Major Lifestyle Interaction
Caffeine-containing Foods/Beverages and Matulane 50mg Capsule(Procarbazine Hydrochloride)
Caffeine-containing Foods/Beverages and Procarbazine Hydrochloride(Procarbazine Hydrochloride)
Try to limit caffeine intake while taking Procarbazine. Side effects from Procarbazine may get worse if you take Caffeine, like increased blood pressure, confusion, restlessness, or other side effects. All preparations containing caffeine should be used sparingly such as tea, coffee, chocolate, cola, or 'stay awake' products. Some nonprescription medicines also contain caffeine and should not be taken along with Procarbazine.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
Visit the Drug Summary page where you can:
  • Get answers to Frequently Asked Questions (FAQs)
  • Find other class related drugs
  • Find additional patient usage statistics
Learn More
Patient Experiences with Matulane

Be the first to share your experience!

We want to help our customers stay educated about the medications they are taking. Submit your own observations and experiences to benefit others.

Average Scores
Easy to Take 
0 / 5
0 / 5
Works as Intended 
0 / 5
0 / 5
Tolerable 
0 / 5
0 / 5