Methotrexate Sodium Lyophilisate For Solution For Injection 1G Drug Medication Dosage Information
show timeout overlay link

Your Session Is About to Expire

This online session is about to expire due to inactivity. Click Continue to return to page.

  • myWeekly Ad

Methotrexate Sodium: Lyophilisate for solution for injection (1g)

Also see:
  • Get answers to Frequently Asked Questions (FAQs)
  • Find other class related drugs
  • Find additional patient usage statistics

Visit Drug Summary Page
Drug Image file default-drug-image.png


What is this Medicine?

METHOTREXATE (METH oh TREX ate) is a chemotherapy drug. This medicine affects cells that are rapidly growing, such as cancer cells and cells in your mouth and stomach. It is used to treat many cancers and other medical conditions. It is used for leukemias, lymphomas, breast cancer, lung cancer, head and neck cancers, and other cancers. This medicine also works on the immune system and is commonly used to treat psoriasis and rheumatoid arthritis.

In-Depth Information
Select a Medication

Methotrexate Sodium 1g Powder for Injection

NDC: 617030139
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Mycosis Fungoides, Non-Hodgkin's Lymphoma (NHL), Small Cell Lung Cancer (SCLC), Choriocarcinoma, Acute Lymphocytic Leukemia (ALL), Cutaneous T-cell Lymphoma (CTCL), Leukemic Meningitis, Trophoblastic Disease, Osteogenic Sarcoma, Breast Cancer, Lung Cancer, Psoriasis, Burkitt's Lymphoma, Hydatidiform Mole, Polyarticular Juvenile Idiopathic Arthritis, Head And Neck Cancer

Sometimes used for but not FDA approved for the following conditions:
Pregnancy Termination, Systemic Lupus Erythematosus (SLE), Dermatomyositis, Carcinomatous Meningitis, Penile Cancer, Ectopic Pregnancy, Crohn's Disease, Desmoid Tumor, Asthma, Polymyositis, Bladder Cancer, Ulcerative Colitis

Methotrexate Sodium 1g Powder for Injection

Reported Side Effects for Methotrexate Sodium 1g Powder for Injection

Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Vaginal Discharge Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Eye Irritation Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Excessive Sweating Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Headache Incidence:
<1.2%*
Severity: MILD
Onset: EARLY
Fever Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Nose Bleed Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Painful Urination Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Cough Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Joint Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Decreased Appetite Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Anemia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Infection Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Ringing In Ears Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Liver Disease Incidence:
0.1%*
Severity: SEVERE
Onset: DELAYED
Skin Rash Incidence:
0.2-3.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
0.2-3.0%*
Severity: MILD
Onset: EARLY
Hair Loss Incidence:
0.5-10.0%*
Severity: MILD
Onset: DELAYED
Loose Stools Incidence:
1.0-11.0%*
Severity: MILD
Onset: EARLY
Itching Incidence:
1.0-3.0%*
Severity: MILD
Onset: RAPID
Lung Inflammation Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Pancytopenia Incidence:
1.0-3.0%*
Severity: SEVERE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: DELAYED
Mouth Ulcers Incidence:
2.0-11.0%*
Severity: MODERATE
Onset: DELAYED
Photosensitivity Incidence:
3.0-10.0%*
Severity: MILD
Onset: DELAYED
Low Platelet Count Incidence:
3.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
10.0-11.0%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
10.0-11.0%*
Severity: MILD
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
14.0-15.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Methotrexate Sodium 1g Powder for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Methotrexate Sodium 1g Powder for Injection(Methotrexate Sodium)
Alcohol and Methotrexate(Methotrexate Sodium)
Ingesting alcoholic beverages during methotrexate therapy may increase the risk for liver-related problems. You should avoid alcoholic drinks during methotrexate therapy.
Moderate Lifestyle Interaction
Food and Methotrexate Sodium 1g Powder for Injection(Methotrexate Sodium)
Food and Methotrexate(Methotrexate Sodium)
Certain food or drink such as cola may increase the risk of methotrexate side effects. Tell your doctor if you drink soft drinks before you take methotrexate. Immediately report any ununsual symptom such as stomach pain, sore throat, fever, mouth sores, or problems with urination.
Moderate Lifestyle Interaction
Foods that acidify the urine and Methotrexate Sodium 1g Powder for Injection(Methotrexate Sodium)
Foods that acidify the urine and Methotrexate(Methotrexate Sodium)
Certain food or drink such as cola may increase the risk of methotrexate side effects. Tell your doctor if you drink soft drinks before you take methotrexate. Immediately report any ununsual symptom such as stomach pain, sore throat, fever, mouth sores, or problems with urination.
Pregnancy & Lactation Information
FIRST Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

SECOND Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

THIRD Trimester

Class X - Adequate well-controlled or observational studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities or risks. The use of the product is contraindicated in women who are or may become pregnant.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


Learning More About
Visit the Drug Summary page where you can:
  • Get answers to Frequently Asked Questions (FAQs)
  • Find other class related drugs
  • Find additional patient usage statistics
Learn More
Patient Experiences with Methotrexate Sodium

We want to help you stay educated about the medications you are taking. View other
patient's observations and share your own.

Be sure to consult your health care provider before taking any medications. Other
patient's comments should not be considered medical advice or health care provider
recommendations.