Metronidazole Oral Capsule 375Mg Drug Medication Dosage Information
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Metronidazole: Oral capsule (375mg)

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Drug Image file DrugItem_9203.JPG
Metronidazole 375mg Cap
Pliva Inc a Division of Teva USA
Pill Identification: PLIVA 375 mg 

What is this Medicine?

METRONIDAZOLE (me troe NI da zole) is an antiinfective. It is used to treat certain kinds of bacterial and protozoal infections. It will not work for colds, flu, or other viral infections.

Similar Brand Name Drugs : Flagyl: Oral capsule (375mg)
CVS Pharmacy Patient Statistics for Metronidazole: Oral capsule(375mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
Select a Medication

Metronidazole 375mg Capsule

NDC: 501110884
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Pneumonia, Peritonitis, Meningitis, Empyema, Intraabdominal Infections, Septicemia, Bone And Joint Infections, Endocarditis, Intraabdominal Abscess, Brain Abscess, Diabetic Foot Ulcer, Trichomoniasis, Gynecologic Infections, Skin And Skin Structure Infections, Endomyometritis, Hepatic Abscess, Endometritis, Lower Respiratory Tract Infections, Tubo-ovarian Abscess, Lung Abscess

Sometimes used for but not FDA approved for the following conditions:
Amebiasis, Giardiasis

Storage Information
Protect from light
Store between 59 to 77 degrees F
Metronidazole 375mg Capsule
Drug Image file DrugItem_9203.JPG
Pliva Inc a Division of Teva USA
Pill Identification: PLIVA 375 mg 
Shape: capsule
Color: green

Reported Side Effects for Metronidazole 375mg Capsule

Infection Incidence:
<7.0%*
Severity: MILD
Onset: DELAYED
Flu Incidence:
<6.0%*
Severity: MILD
Onset: DELAYED
Vomiting Incidence:
<4.0%*
Severity: MILD
Onset: EARLY
Back Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Diaphoresis Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
<4.0%*
Severity: MILD
Onset: EARLY
Increased Urination Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Rhinitis Incidence:
<4.0%*
Severity: MILD
Onset: EARLY
Urine Discoloration Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Depression Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Painful Urination Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Inability To Sleep Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Appetite Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Itching Incidence:
<6.0%*
Severity: MILD
Onset: RAPID
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Vaginal Infection Incidence:
<15.0%*
Severity: MODERATE
Onset: DELAYED
Acne Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Yeast Infection Incidence:
0.2-12.0%*
Severity: MODERATE
Onset: DELAYED
Skin Rash Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
1.0-4.0%*
Severity: MILD
Onset: EARLY
Stuffy Nose Incidence:
1.1%*
Severity: MILD
Onset: EARLY
Menstrual Cramps Incidence:
1.2-3.0%*
Severity: MILD
Onset: DELAYED
Sinus Infection Incidence:
1.4-3.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
1.6-12.0%*
Severity: MILD
Onset: EARLY
Sore Throat Incidence:
2.0-3.1%*
Severity: MILD
Onset: DELAYED
Dry Mouth Incidence:
2.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
2.2-18.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
4.0-5.0%*
Severity: MILD
Onset: EARLY
Itching Around The Anus Incidence:
5.0%*
Severity: MILD
Onset: EARLY
Metallic Taste Incidence:
9.0%*
Severity: MILD
Onset: EARLY
Metallic Taste Incidence:
9.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Metronidazole 375mg Capsule

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Severe Lifestyle Interaction
Alcohol and Metronidazole 375mg Capsule(Metronidazole)
Alcohol and Metronidazole(Metronidazole)
When Alcohol is taken by patients receiving Metronidazole, an extremely unpleasant reaction can occur. This reaction includes flushing, throbbing headache, nausea, vomiting, sweating, thirst, and other effects that may last from 30 minutes to several hours. You should not drink alcoholic beverages or use medicines that contain a large amount of alcohol while taking Metronidazole. Also continue to avoid Alcohol for about 2-3 days after stopping Metronidazole. Interactions with Metronidazole vaginal or topical skin products are not likely.
Major Lifestyle Interaction
Food and Metronidazole 375mg Capsule(Metronidazole)
Food and Metronidazole(Metronidazole)
Most forms of metronidazole may be taken without regard to meals or food. However, extended-release metronidazole tablets, like Flagyl ER, should be taken on an empty stomach 1 hour before or 2 hours after meals. Do not use alcoholic beverages (or take alcohol-containing medicines) while taking or within 2-3 days after stopping Metronidazole to limit the possibility of side effects. When Alcohol is taken by patients receiving Metronidazole, an extremely unpleasant reaction can occur. This reaction includes flushing, throbbing headache, nausea, vomiting, sweating, thirst, and other effects that may last from 30 minutes to several hours. Interactions with Metronidazole vaginal or topical skin products are not likely.
Pregnancy & Lactation Information
FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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