Mexiletine Hydrochloride Oral Capsule 150Mg Drug Medication Dosage Information
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Mexiletine Hydrochloride: Oral capsule (150mg)

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Drug Image file DrugItem_2590.JPG
Mexiletine 150mg Cap
Teva Pharmaceuticals USA Inc
Pill Identification: N 739 150 

What is this Medicine?

MEXILETINE (mex IL e teen) is an antiarrhythmic agent. This medicine is used to treat irregular heart rhythm and can slow rapid heartbeats. It can help your heart to return to and maintain a normal rhythm. Because of the side effects caused by this medicine, it is usually used for heartbeat problems that may be life-threatening.

CVS Pharmacy Patient Statistics for Mexiletine Hydrochloride: Oral capsule(150mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
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Mexiletine Hydrochloride 150mg Capsule

NDC: 000938739
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Ventricular Tachycardia

Sometimes used for but not FDA approved for the following conditions:
Neuropathic Pain, Diabetic Neuropathy

Storage Information
Store at room temperature (between 59 to 86 degrees F)
Mexiletine Hydrochloride 150mg Capsule
Drug Image file DrugItem_2590.JPG
Teva Pharmaceuticals USA Inc
Pill Identification: N 739 150 
Shape: capsule
Color: orange,tan

Reported Side Effects for Mexiletine Hydrochloride 150mg Capsule

Ringing In Ears Incidence:
<2.4%*
Severity: MILD
Onset: DELAYED
Retaining Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Dry Skin Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
No White Blood Cells Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Difficulty Swallowing Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Intestinal Bleeding Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Psychosis Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Convulsions Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Fainting Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Confusion Incidence:
<2.6%*
Severity: MODERATE
Onset: EARLY
Diaphoresis Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Throat Ulcers Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hallucinations Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Death Of Liver Tissue Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hiccups Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Impotence (erectile Dysfunction) Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Sexual Desire Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Lupus-like Symptoms Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Feeling Sick Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Stomach Ulcer Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Weakness Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Decreased Memory Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Tired Incidence:
<3.8%*
Severity: MILD
Onset: EARLY
Swelling Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Slow Heart Beat Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Heart Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hot Flashes Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
High Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Low Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Sore Throat Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Heart Block Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Low Platelet Count Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Abnormal Heart Rhythm Incidence:
1.0-1.9%*
Severity: MODERATE
Onset: EARLY
Stomach Pain Incidence:
1.2%*
Severity: MILD
Onset: EARLY
Fever Incidence:
1.2%*
Severity: MILD
Onset: EARLY
Joint Pain Incidence:
1.7%*
Severity: MILD
Onset: DELAYED
Chest Pain Incidence:
1.7%*
Severity: MODERATE
Onset: EARLY
Paresthesias Incidence:
2.4-3.8%*
Severity: MILD
Onset: DELAYED
Depression Incidence:
2.4%*
Severity: MODERATE
Onset: DELAYED
Chest Pain Incidence:
2.6-7.5%*
Severity: MODERATE
Onset: EARLY
Dry Mouth Incidence:
2.8%*
Severity: MILD
Onset: EARLY
Shortness Of Breath Incidence:
3.3%*
Severity: MODERATE
Onset: EARLY
Skin Rash Incidence:
3.8-4.2%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
4.0%*
Severity: MODERATE
Onset: DELAYED
Rapid Heart Rate Incidence:
4.3%*
Severity: MODERATE
Onset: EARLY
Loose Stools Incidence:
5.2%*
Severity: MILD
Onset: EARLY
Headache Incidence:
5.7-7.5%*
Severity: MILD
Onset: EARLY
Blurred Vision Incidence:
5.7-7.5%*
Severity: MODERATE
Onset: EARLY
Incoordination Incidence:
10.2%*
Severity: MODERATE
Onset: DELAYED
Lightheadedness Incidence:
10.5%*
Severity: MILD
Onset: EARLY
Shaking Incidence:
12.6%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
39.3%*
Severity: MILD
Onset: EARLY
Heartburn Incidence:
39.3%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
39.3%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Mexiletine Hydrochloride 150mg Capsule

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Moderate Lifestyle Interaction
Tobacco and Mexiletine Hydrochloride 150mg Capsule(Mexiletine Hydrochloride)
Tobacco and Mexiletine Hydrochloride(Mexiletine Hydrochloride)
In theory, Tobacco smoking may reduce the effectiveness of Mexilitene, because tobacco smoke contains substances that speed the removal of Mexiletine from the body. Also, Tobacco smoking may increase the blood pressure or contribute to the risk of heart disease and related problems. Alternatively, if you take Mexilitene and suddenly stop Tobacco smoking, you may experience increased or worsening side effects of Mexiletine such as nausea, vomiting, heartburn, stomach upset, dizziness, tremor, or coordination difficulties. Make sure your prescriber is aware that you smoke Tobacco or if you plan to stop smoking. Contact your prescriber immediately if you experience chest pain, palpitations, dizziness, fainting or falling spells, shortness of breath, or change in your usual heart beat (fast, slow, or irregular heart beat) while taking Mexiletine.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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