Motrin Oral Tablet 400Mg Drug Medication Dosage Information
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Motrin: Oral tablet (400mg)

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Drug Image file DrugItem_15494.JPG
Ibuprofen 400mg Tab
Dr. Reddy's Laboratories, Inc.
Pill Identification: 4I 
Drug Image file DrugItem_15495.JPG
Ibuprofen 400mg Tab
Legacy Pharmaceutical Packaging, LLC
Pill Identification: 4I 
Drug Image file DrugItem_14053.JPG
Ibuprofen 400mg Tab
PD-RX Pharmaceuticals Incorporated
Pill Identification: IP 464 
Drug Image file DrugItem_13606.JPG
Ibuprofen 400mg Tab
Major Pharmaceuticals Inc
Pill Identification: IP 464 
Drug Image file DrugItem_3380.JPG
Ibuprofen 400mg Tab
Interpharm Inc
Pill Identification: IP 131  |  400
Drug Image file DrugItem_10565.JPG
Ibuprofen 400mg Tab
Amneal Pharmaceuticals
Pill Identification: IP 131  |  400
Drug Image file DrugItem_9771.JPG
Ibuprofen 400mg Tab
Mylan Institutional LLC formerly UDL Laboratories Inc
Pill Identification: IBU 400 
Drug Image file DrugItem_10793.JPG
Ibuprofen 400mg Tab
Major Pharmaceuticals Inc
Pill Identification: IBU 400 
Drug Image file DrugItem_15496.JPG
Ibuprofen 400mg Tab
McKesson Packaging Inc
Pill Identification: 4I 
Drug Image file DrugItem_10092.JPG
Ibuprofen 400mg Tab
Perrigo Pharmaceuticals Company
Pill Identification: L373 
Drug Image file DrugItem_17004.JPG
Ibuprofen 400mg Tab
American Health Packaging
Pill Identification: IP 464 
Drug Image file DrugItem_16764.JPG
Ibuprofen 400mg Tab
Major Pharmaceuticals Inc
Pill Identification: 4I 
Drug Image file DrugItem_3124.JPG
Ibuprofen 400mg Tab
United Research Laboratories, Inc. a subsidiary of Sun Pharmaceutical Industries, Inc.
Pill Identification: IP 131  |  400
Drug Image file DrugItem_15497.JPG
Ibuprofen 400mg Tab
American Health Packaging
Pill Identification: 4I 
Drug Image file DrugItem_5012.JPG
Ibuprofen 400mg Tab
Actavis Inc. formerly Watson Pharmaceuticals Inc
Pill Identification: IP 131  |  400
Drug Image file DrugItem_12471.JPG
Ibuprofen 400mg Tab
PD-RX Pharmaceuticals
Pill Identification: IP 131  |  400
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Motrin 400mg Tab
Pfizer US Pharmaceuticals
Pill Identification: MOTRIN 400 
Drug Image file DrugItem_16076.JPG
Ibuprofen 400mg Tab
AvKARE, Inc.
Pill Identification: IP 464 
Drug Image file DrugItem_1370.JPG
Ibuprofen 400mg Tab
Greenstone Ltd
Pill Identification: G 400 
Drug Image file DrugItem_18223.JPG
Ibuprofen 400mg Tab
McKesson Packaging
Pill Identification: IP 464 
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IBU 400mg Tab
Par Pharmaceutical Inc
Pill Identification: IBU 400 
Drug Image file DrugItem_5248.JPG
IBU 400mg Tab
Par Pharmaceutical Inc
Pill Identification: IBU 400 
Drug Image file DrugItem_13605.JPG
Ibuprofen 400mg Tab
Amneal Pharmaceuticals
Pill Identification: IP 464 

What is this Medicine?

IBUPROFEN (eye BYOO proe fen) is a non-steroidal anti-inflammatory drug (NSAID). It is used for dental pain, fever, headaches or migraines, osteoarthritis, rheumatoid arthritis, or painful monthly periods. It can also relieve minor aches and pains caused by a cold, flu, or sore throat.

In-Depth Information

Motrin 400mg Tablet

NDC: 000097385
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Fever, Dysmenorrhea, Migraine, Mild Pain, Headache, Juvenile Rheumatoid Arthritis (JRA)/juvenile Idiopathic Arthritis (JIA), Moderate Pain, Osteoarthritis, Rheumatoid Arthritis

Sometimes used for but not FDA approved for the following conditions:
Cystic Fibrosis, Psoriatic Arthritis, Ankylosing Spondylitis, Gouty Arthritis

Storage Information
Store at controlled room temperature (between 68 and 77 degrees F)
Motrin 400mg Tablet
Drug Image file DrugItem_6987.JPG
Pfizer US Pharmaceuticals
Pill Identification: MOTRIN 400 
Shape: round
Color: white

Reported Side Effects for Motrin 400mg Tablet

Eosinophilia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Emotional Lability Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
<10.0%*
Severity: MODERATE
Onset: DELAYED
Double Vision Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Conjunctivitis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Confusion Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Blistery Rash Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Blurred Vision Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Low Kidney Function Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Brain Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Abnormal Heart Rhythm Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Inceased Urination Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Yellow Skin Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Visual Impairment Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Lyell'S Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Scotomata Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Kidney Damage Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Kidney Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Pseudotumor Cerebri Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Photosensitivity Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Stomach Ulcer Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Heavy Menstrual Period Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Melena Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Deafness Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hallucinations Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Gynecomastia Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Electrolyte Imbalance Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Inability To Sleep Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Low Blood Sugar Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
High Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Hemolytic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Heart Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Erythema Multiforme Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Nose Bleed Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Drowsiness Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Bladder Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Slow Heart Beat Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Aplastic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Lazy Eye Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Hair Loss Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
No White Blood Cells Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Cataracts Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Dry Mouth Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Dry Eyes Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Intestinal Bleeding Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hole In Intestines Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Blood In The Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cells Incidence:
<13.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Optic Nerve Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Itching Incidence:
<10.0%*
Severity: MILD
Onset: RAPID
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Serum Sickness Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Stevens-Johnson Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Low Platelet Count Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
1.0-3.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Anemia Incidence:
1.0-20.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Skin Rash Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Prolonged Bleeding Time Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Stomach Pain Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Swelling Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Gas Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Ringing In Ears Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Rash With Pustules Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Heartburn Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Fluid Retention Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Motrin 400mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Motrin 400mg Tablet(Ibuprofen)
Alcohol and Nonsteroidal antiinflammatory drugs (systemic)(Ibuprofen)
Side effects from this drug may get worse if you drink alcohol-containing drinks. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. It is best to limit or avoid alcohol containing drinks while taking this drug, even with short term use. Many non-prescription products for headaches, pain, arthritis, or sinus pain contain drugs that may cause stomach problems along with alcohol; closely read labels before taking any medicines with alcohol-containing drinks.
Moderate Lifestyle Interaction
Tobacco and Motrin 400mg Tablet(Ibuprofen)
Tobacco and Nonsteroidal antiinflammatory drugs (systemic)(Ibuprofen)
Side effects from Nonsteroidal anti-inflammatory drugs may get worse if you use tobacco-containing products such as cigarettes. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. Many non-prescription products contain NSAIDs; closely read labels before taking any medicines. Eye or Skin products containing NSAIDs should not interact with tobacco.
Moderate Lifestyle Interaction
Marijuana and Motrin 400mg Tablet(Ibuprofen)
Marijuana and Nonsteroidal antiinflammatory drugs (systemic)(Ibuprofen)
Although an interaction is possible, these drugs may be used together. In therory, the actions of Marijuana, Medical may be decreased if you take Nonsteroidal Antiinflammatory Drugs (NSAIDs). However, the importance of this interaction is not known. Patients receiving this drug combination may notice decreased euphoria and heart rate.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Compatible - This drug is generally safe to take by nursing mothers.


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Patient Experiences with Motrin

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