Naproxen Oral Tablet 220Mg Drug Medication Dosage Information
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Naproxen: Oral tablet (220mg)

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Naproxen Sodium 220mg Tab
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Naproxen Sodium 220mg Tab
Major Pharmaceuticals Inc
Pill Identification: I 3 
Drug Image file default-drug-image.png
Naproxen Sodium 220mg Tab

What is this Medicine?

NAPROXEN (na PROX en) is a non-steroidal anti-inflammatory drug (NSAID). It is used to reduce swelling and to treat pain. This medicine may be used for dental pain, headache, or painful monthly periods. It is also used for painful joint and muscular problems such as arthritis, tendinitis, bursitis, and gout.

CVS Pharmacy Patient Statistics for Naproxen: Oral tablet(220mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
Select a Medication

Naproxen Sodium 220mg Caplet

NDC: 005364113
  • Over the Counter
    (Prescription Not Required)
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Tendinitis, Myalgia, Arthralgia, Mild Pain, Dental Pain, Osteoarthritis, Rheumatoid Arthritis, Moderate Pain, Gouty Arthritis, Fever, Dysmenorrhea, Bursitis, Ankylosing Spondylitis, Headache, Juvenile Rheumatoid Arthritis (JRA)/juvenile Idiopathic Arthritis (JIA)

Storage Information
Store at controlled room temperature (between 68 and 77 degrees F)
Avoid excessive humidity
Avoid excessive heat (above 104 degrees F)
Naproxen Sodium 220mg Caplet

Reported Side Effects for Naproxen Sodium 220mg Caplet

Broken Bones Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Breathing Difficulties Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Blistery Rash Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Chest Pain Incidence:
<3.0%*
Severity: MODERATE
Onset: EARLY
Chills Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Confusion Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Conjunctivitis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Diaphoresis Incidence:
<3.0%*
Severity: MILD
Onset: EARLY
Double Vision Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
<9.0%*
Severity: MILD
Onset: EARLY
Bruise Incidence:
<3.0%*
Severity: MILD
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
<15.0%*
Severity: MODERATE
Onset: DELAYED
Emotional Lability Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Eosinophilia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Belching Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Rash Of Red Skin Bumps Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Throat Ulcers Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Back Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Glomerulonephritis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Tongue Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Glycosuria Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Infection Incidence:
<9.0%*
Severity: MILD
Onset: DELAYED
Yellow Skin Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Muscle Cramps Incidence:
<3.0%*
Severity: MILD
Onset: DELAYED
Heart Attack Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Fluid Retention Incidence:
<3.0%*
Severity: MODERATE
Onset: DELAYED
Inceased Urination Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Decreased Breathing Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Fainting Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Inflamed Blood Vessels Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Vomiting Incidence:
<10.0%*
Severity: MILD
Onset: EARLY
Loss Of Memory Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Abnormal Heart Rhythm Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Inflamed Brain Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Weakness Incidence:
<3.0%*
Severity: MILD
Onset: DELAYED
Low Kidney Function Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Blurred Vision Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Stomach Ulcer Incidence:
<10.0%*
Severity: SEVERE
Onset: DELAYED
Peripheral Vasodilation Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Irritated Blood Vessels Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Photosensitivity Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Prolonged Bleeding Time Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Drooping Eyelids Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Bruises Incidence:
<3.0%*
Severity: MILD
Onset: DELAYED
Pus In Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Skin Rash Incidence:
<9.0%*
Severity: MILD
Onset: EARLY
Kidney Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Kidney Damage Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Skin Necrosis Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Skin Ulcer Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Removal Of Spleen Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Brain Bruise Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Visual Impairment Incidence:
<3.0%*
Severity: SEVERE
Onset: EARLY
Weight Loss Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Hallucinations Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Deafness Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Vomiting Of Blood Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Death Of Liver Tissue Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Enlarged Liver Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Excessive Mucle Tone Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Increased Urination Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Kidney Inflammation Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Secretion Of Tears Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Enlarged Lymph Nodes Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Feeling Sick Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Melena Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Heavy Menstrual Period Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Muscle Paralysis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Weakness Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Nighttime Urination Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Mouth Sores Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Rapid Heart Rate Incidence:
<3.0%*
Severity: MODERATE
Onset: EARLY
Pancytopenia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
<3.0%*
Severity: MILD
Onset: DELAYED
Menstrual Cramps Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
<14.0%*
Severity: MILD
Onset: EARLY
Painful Urination Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Eczema Vaccinatum Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Swelling Incidence:
<9.0%*
Severity: MODERATE
Onset: DELAYED
Nose Bleed Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Erythema Multiforme Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Throat Inflammation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Exfoliative Dermatitis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Fever Incidence:
<3.0%*
Severity: MILD
Onset: EARLY
Gas Incidence:
<10.0%*
Severity: MILD
Onset: EARLY
Inflamed Stomach Incidence:
<3.0%*
Severity: MODERATE
Onset: DELAYED
Heart Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hemolytic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
High Potassium Level Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
High Blood Pressure Incidence:
<3.0%*
Severity: MODERATE
Onset: EARLY
High Uric Acid Level Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low Blood Sugar Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Low Potassium Levels Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Acne Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Hair Loss Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Lazy Eye Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Severe Allergy Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Anemia Incidence:
<3.0%*
Severity: MODERATE
Onset: DELAYED
Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Angioedema Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Decreased Appetite Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Nervousness Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Aplastic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Joint Pain Incidence:
<3.0%*
Severity: MILD
Onset: DELAYED
Bone Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Cholecystitis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Gallstones Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Colon Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Coma Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Allergic Skin Reaction Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Cough Incidence:
<3.0%*
Severity: MILD
Onset: DELAYED
Bladder Infection Incidence:
<3.0%*
Severity: MODERATE
Onset: DELAYED
Dehydration Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Depression Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
<9.0%*
Severity: MILD
Onset: EARLY
Mouth Ulcers Incidence:
<3.0%*
Severity: MODERATE
Onset: DELAYED
Low Platelet Count Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Shaking Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Uncontrolled Urination Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Retaining Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Vaginal Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Balance Problems Incidence:
<3.0%*
Severity: MILD
Onset: EARLY
Dry Skin Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Dry Mouth Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
No White Blood Cells Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Bleeding Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Bundle-branch Block Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Intestinal Bleeding Incidence:
<10.0%*
Severity: SEVERE
Onset: DELAYED
Hole In Intestines Incidence:
<10.0%*
Severity: SEVERE
Onset: DELAYED
Blood In The Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Increased Blood Sugar Incidence:
<3.0%*
Severity: MODERATE
Onset: DELAYED
Eye Pain Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Decreased Urination Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Inflamed Nerve Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Nephrotic Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Pain Incidence:
<3.0%*
Severity: MILD
Onset: EARLY
Lung Inflammation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Protein In The Urine Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Itching Incidence:
<9.0%*
Severity: MILD
Onset: RAPID
Fluid In Lungs Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Migraine Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Electrolyte Imbalance Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Eye Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Inability To Sleep Incidence:
<3.0%*
Severity: MILD
Onset: EARLY
Stevens-Johnson Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Rhinitis Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
3.0-15.0%*
Severity: MILD
Onset: EARLY
Sore Throat Incidence:
3.0-9.0%*
Severity: MILD
Onset: DELAYED
Constipation Incidence:
3.0-9.0%*
Severity: MODERATE
Onset: DELAYED
Ringing In Ears Incidence:
3.0-9.0%*
Severity: MILD
Onset: DELAYED
Heartburn Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
3.0-9.0%*
Severity: MILD
Onset: EARLY
Back Pain Incidence:
3.0-9.0%*
Severity: MILD
Onset: DELAYED
Sinus Infection Incidence:
3.0-9.0%*
Severity: MILD
Onset: DELAYED
Shortness Of Breath Incidence:
3.0-9.0%*
Severity: MODERATE
Onset: EARLY
Flu Incidence:
10.0%*
Severity: MILD
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Naproxen Sodium 220mg Caplet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Naproxen Sodium 220mg Caplet(Naproxen Sodium)
Alcohol and Nonsteroidal antiinflammatory drugs (systemic)(Naproxen Sodium)
Side effects from this drug may get worse if you drink alcohol-containing drinks. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. It is best to limit or avoid alcohol containing drinks while taking this drug, even with short term use. Many non-prescription products for headaches, pain, arthritis, or sinus pain contain drugs that may cause stomach problems along with alcohol; closely read labels before taking any medicines with alcohol-containing drinks.
Moderate Lifestyle Interaction
Tobacco and Naproxen Sodium 220mg Caplet(Naproxen Sodium)
Tobacco and Nonsteroidal antiinflammatory drugs (systemic)(Naproxen Sodium)
Side effects from Nonsteroidal anti-inflammatory drugs may get worse if you use tobacco-containing products such as cigarettes. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. Many non-prescription products contain NSAIDs; closely read labels before taking any medicines. Eye or Skin products containing NSAIDs should not interact with tobacco.
Moderate Lifestyle Interaction
Marijuana and Naproxen Sodium 220mg Caplet(Naproxen Sodium)
Marijuana and Nonsteroidal antiinflammatory drugs (systemic)(Naproxen Sodium)
Although an interaction is possible, these drugs may be used together. In therory, the actions of Marijuana, Medical may be decreased if you take Nonsteroidal Antiinflammatory Drugs (NSAIDs). However, the importance of this interaction is not known. Patients receiving this drug combination may notice decreased euphoria and heart rate.
Pregnancy & Lactation Information
Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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