Narcotic Cough/Cold Preparations Oral Syrup 200-5-60Mg Drug Medication Dosage Information
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Narcotic Cough/Cold Preparations: Oral syrup (200-5-60mg)

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What is this Medicine?

GUAIFENESIN; HYDROCODONE; PSEUDOEPHEDRINE (gwye FEN e sin; hye droe KOE done; soo doe e FED rin) is used to treat cough and congestion due to colds and other respiratory infections. This medicine will not treat an infection.

In-Depth Information
Select a Medication

Poly-Tussin XP 200mg-5mg-60mg/5ml Syrup

NDC: 005510925
  • Prescription Required
  • Federally Controlled Drug
    (CSA Schedule)




Labeled but not FDA approved for the following conditions:
Cough, Nasal Congestion

Poly-Tussin XP 200mg-5mg-60mg/5ml Syrup

Reported Side Effects for Poly-Tussin XP 200mg-5mg-60mg/5ml Syrup

Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Low Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Hives Incidence:
<3.0%*
Severity: MILD
Onset: RAPID
Skin Rash Incidence:
1.0-5.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Heartburn Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Flushing Incidence:
1.0-5.0%*
Severity: MILD
Onset: RAPID
Headache Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Hot Flashes Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: EARLY
Excessive Sweating Incidence:
1.0-5.0%*
Severity: MILD
Onset: DELAYED
Lightheadedness Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Itching Incidence:
1.0-5.0%*
Severity: MILD
Onset: RAPID
Dry Mouth Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Drowsiness Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Miosis Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
>10.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Poly-Tussin XP 200mg-5mg-60mg/5ml Syrup

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Poly-Tussin XP 200mg-5mg-60mg/5ml Syrup(Hydrocodone Bitartrate)
Alcohol and CNS Depressants(Hydrocodone Bitartrate)
Avoid alcohol-containing drinks while taking this medicine. Using this drug along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how this drug affects you, and especially if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Major Lifestyle Interaction
Grapefruit juice and Poly-Tussin XP 200mg-5mg-60mg/5ml Syrup(Hydrocodone Bitartrate)
Grapefruit juice and Hydrocodone(Hydrocodone Bitartrate)
Side effects from Hydrocodone may get worse if you eat or drink grapefruit juice. Talk to your doctor first. Contact your doctor right away if you have slurred speech, confusion, weakness, or trouble breathing. Do not drive or operate machinery until you know how this affects you.
Moderate Lifestyle Interaction
Caffeine-containing Foods/Beverages and Poly-Tussin XP 200mg-5mg-60mg/5ml Syrup(Pseudoephedrine Hydrochloride)
Caffeine-containing Foods/Beverages and Pseudoephedrine(Pseudoephedrine Hydrochloride)
Limit caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Pseudoephedrine. Also avoid medicines containing additional Caffeine whenever possible. Side effects from Pseudoephedrine may get worse if you take excessive Caffeine. Taking a high amount of Caffeine can increase the risk of nausea, nervousness, palpitations, problems with sleep, rapid heartbeat, tremor, or other side effects.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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