Nexavar Oral Tablet 200Mg Drug Medication Dosage Information
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Nexavar: Oral tablet (200mg)

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What is this Medicine?

SORAFENIB (soe RAF e nib) is a medicine that targets proteins in cancer cells and stops the cancer cells from growing. It is used to treat liver cancer, kidney cancer, and thyroid cancer.

In-Depth Information
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Nexavar 200mg Tablet

NDC: 504190488
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Thyroid Cancer, Renal Cell Cancer, Hepatocellular Cancer

Sometimes used for but not FDA approved for the following conditions:
Malignant Melanoma

Storage Information
Store in a dry place
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Nexavar 200mg Tablet

Reported Side Effects for Nexavar 200mg Tablet

Underactive Thyroid Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Nephrotic Syndrome Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Gynecomastia Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Lung Inflammation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Protein In The Urine Incidence:
<10.0%*
Severity: MODERATE
Onset: DELAYED
Itching Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Ringing In Ears Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Dry Skin Incidence:
<0.5%*
Severity: SEVERE
Onset: DELAYED
Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Vomiting Incidence:
<2.0%*
Severity: SEVERE
Onset: EARLY
Long Qt Syndrome Incidence:
<0.1%*
Severity: MODERATE
Onset: RAPID
Hole In Intestines Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Flu Incidence:
<10.0%*
Severity: MILD
Onset: DELAYED
Bleeding In The Brain Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Yellow Skin Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Heart Attack Incidence:
<10.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Cramps Incidence:
<10.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Acute Lung Injury Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Decreased Appetite Incidence:
<3.0%*
Severity: SEVERE
Onset: DELAYED
Weight Loss Incidence:
<6.0%*
Severity: SEVERE
Onset: DELAYED
Cholangitis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Cholecystitis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Constipation Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Depression Incidence:
<10.0%*
Severity: MODERATE
Onset: DELAYED
Shortness Of Breath Incidence:
<4.0%*
Severity: SEVERE
Onset: EARLY
High Blood Pressure Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Overactive Thyroid Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Kidney Failure Incidence:
<10.0%*
Severity: SEVERE
Onset: DELAYED
Impotence (erectile Dysfunction) Incidence:
<10.0%*
Severity: MODERATE
Onset: DELAYED
High Bilirubin Level Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Brain Deterioration Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Headache Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Low Blood Sodium Levels Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Dehydration Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Stomach Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Eczema Vaccinatum Incidence:
0.1-0.9%*
Severity: SEVERE
Onset: DELAYED
Erythema Multiforme Incidence:
0.1-0.9%*
Severity: SEVERE
Onset: DELAYED
Hoarseness Incidence:
0.5%*
Severity: SEVERE
Onset: DELAYED
Heartburn Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
High Amylase Levels Incidence:
1.0-2.0%*
Severity: SEVERE
Onset: DELAYED
Hyperkeratosis Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Flushing Incidence:
1.0-10.0%*
Severity: MILD
Onset: RAPID
Acne Incidence:
1.0-10.0%*
Severity: MILD
Onset: DELAYED
Upset Stomach Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Exfoliative Dermatitis Incidence:
1.0-10.0%*
Severity: SEVERE
Onset: DELAYED
Fever Incidence:
1.0%*
Severity: SEVERE
Onset: EARLY
Muscle Pain Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Runny Nose Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Low Platelet Count Incidence:
1.0-4.0%*
Severity: SEVERE
Onset: DELAYED
Dry Mouth Incidence:
1.0-10.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
1.0-9.0%*
Severity: SEVERE
Onset: EARLY
Bleeding Incidence:
1.0-2.0%*
Severity: SEVERE
Onset: EARLY
Difficulty Swallowing Incidence:
1.0-10.0%*
Severity: MODERATE
Onset: DELAYED
Low Potassium Levels Incidence:
1.3-2.4%*
Severity: SEVERE
Onset: DELAYED
Heart Failure Incidence:
1.9%*
Severity: SEVERE
Onset: DELAYED
Joint Pain Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Loose Stools Incidence:
2.0-10.0%*
Severity: SEVERE
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
2.0-4.0%*
Severity: SEVERE
Onset: DELAYED
Mouth Ulcers Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
Low Calcium Levels Incidence:
2.0%*
Severity: SEVERE
Onset: DELAYED
High Blood Pressure Incidence:
3.0-10.0%*
Severity: SEVERE
Onset: EARLY
Secondary Malignancy Incidence:
3.0%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cells Incidence:
5.0%*
Severity: SEVERE
Onset: DELAYED
Tired Incidence:
5.0-10.0%*
Severity: SEVERE
Onset: EARLY
Metallic Taste Incidence:
6.0%*
Severity: MILD
Onset: EARLY
Nose Bleed Incidence:
7.0%*
Severity: MILD
Onset: DELAYED
Intestinal Bleeding Incidence:
>10.0%*
Severity: SEVERE
Onset: DELAYED
Infection Incidence:
>10.0%*
Severity: MILD
Onset: DELAYED
Weakness Incidence:
>10.0%*
Severity: MILD
Onset: DELAYED
Bone Pain Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Low Phosphate Level Incidence:
11.0-13.0%*
Severity: SEVERE
Onset: DELAYED
Low Lymphocytes Incidence:
13.0%*
Severity: SEVERE
Onset: DELAYED
Inflamed Tongue Incidence:
14.0%*
Severity: MODERATE
Onset: EARLY
Skin Rash Incidence:
19.0-40.0%*
Severity: MILD
Onset: EARLY
Hand And Foot Syndrome Incidence:
21.0-30.0%*
Severity: MODERATE
Onset: DELAYED
Low Albumin In Blood Incidence:
59.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

SECOND Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

THIRD Trimester

Class D - Adequate well-controlled or observational studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy may outweigh the potential risk. For example, the drug may be acceptable if needed in a life-threatening situation or serious disease for which safer drugs cannot be used or are ineffective.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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