Olanzapine Powder For Solution For Injection 10Mg Drug Medication Dosage Information
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Olanzapine: Powder for solution for injection (10mg)

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What is this Medicine?

OLANZAPINE (oh LAN za peen) is used to treat schizophrenia, psychotic disorders,and bipolar disorder. Bipolar disorder is also known as manic-depression.

In-Depth Information
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Olanzapine 10mg Powder for Injection

NDC: 007813159
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Mania, Schizophrenia, Bipolar Disorder

Sometimes used for but not FDA approved for the following conditions:
Agitation

Storage Information
Store reconstituted product for up to 1 hour at 68 to 77 degrees F
Protect from light
Do not freeze
Discard unused portion. Do not store for later use.
Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees F
Discard reconstituted product if not used within 1 hour
Olanzapine 10mg Powder for Injection

Reported Side Effects for Olanzapine 10mg Powder for Injection

Tooth Cavities Incidence:
<4.0%*
Severity: MILD
Onset: DELAYED
High Blood Pressure Incidence:
<3.0%*
Severity: MODERATE
Onset: EARLY
Bowel Obstruction Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Osteoporosis Incidence:
<0.1%*
Severity: MODERATE
Onset: DELAYED
Fluid In Lungs Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Sneezing Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Long Qt Syndrome Incidence:
<2.0%*
Severity: MODERATE
Onset: RAPID
Infection Incidence:
<4.0%*
Severity: MILD
Onset: DELAYED
Intestinal Blockage Incidence:
<0.1%*
Severity: SEVERE
Onset: DELAYED
Pseudoparkinsonism Incidence:
<14.0%*
Severity: MODERATE
Onset: DELAYED
Large Pupil Incidence:
<0.1%*
Severity: MILD
Onset: EARLY
Coma Incidence:
<0.1%*
Severity: SEVERE
Onset: EARLY
Fever Incidence:
<6.0%*
Severity: MILD
Onset: EARLY
Hallucinations Incidence:
<3.0%*
Severity: MODERATE
Onset: EARLY
Acne Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Low White Blood Cell Counts Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Irregular Periods Incidence:
0.1-2.0%*
Severity: MILD
Onset: DELAYED
Inceased Urination Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
0.1-5.0%*
Severity: MILD
Onset: EARLY
Photosensitivity Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Peripheral Vasodilation Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: RAPID
Light Menstrual Period Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Brain Attack Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: EARLY
Thoughts Of Suicide Incidence:
0.1-1.0%*
Severity: SEVERE
Onset: DELAYED
Heavy Menstrual Period Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
Fainting Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Decreased Sexual Desire Incidence:
0.1-2.0%*
Severity: MILD
Onset: DELAYED
Vomiting Incidence:
0.1-6.0%*
Severity: MILD
Onset: EARLY
Increased Urination Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Incoordination Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Impotence (erectile Dysfunction) Incidence:
0.1-2.0%*
Severity: MODERATE
Onset: DELAYED
Chills Incidence:
0.1-1.0%*
Severity: MILD
Onset: RAPID
Dysarthria Incidence:
0.1-2.0%*
Severity: MODERATE
Onset: DELAYED
Breast Pain Incidence:
0.1-1.0%*
Severity: MILD
Onset: DELAYED
High Bilirubin Level Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Low Platelet Count Incidence:
0.1-1.0%*
Severity: MODERATE
Onset: DELAYED
Nose Bleed Incidence:
0.1-3.0%*
Severity: MILD
Onset: DELAYED
Swelling Incidence:
0.1-2.0%*
Severity: MODERATE
Onset: DELAYED
Urinary Urgency Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Dry Eyes Incidence:
0.1-1.0%*
Severity: MILD
Onset: EARLY
Hair Loss Incidence:
0.1%*
Severity: MILD
Onset: DELAYED
No Menstrual Periods Incidence:
0.1-2.0%*
Severity: MILD
Onset: DELAYED
Fluid From Breast Incidence:
0.2-0.7%*
Severity: MILD
Onset: DELAYED
Increase In Breast Size Incidence:
0.2-0.7%*
Severity: MILD
Onset: DELAYED
Galactorrhea Incidence:
0.2-0.7%*
Severity: MODERATE
Onset: DELAYED
Gynecomastia Incidence:
0.2-0.7%*
Severity: MILD
Onset: DELAYED
Convulsions Incidence:
0.2-0.9%*
Severity: SEVERE
Onset: DELAYED
Orgasm Dysfunction Incidence:
0.7-2.0%*
Severity: MILD
Onset: DELAYED
Increased Blood Sugar Incidence:
0.9-26.0%*
Severity: MODERATE
Onset: DELAYED
Gas Incidence:
1.0-2.0%*
Severity: MILD
Onset: EARLY
Injection Site Reaction Incidence:
1.0-3.6%*
Severity: MILD
Onset: RAPID
Elevated Hepatic Enzymes Incidence:
1.0-28.0%*
Severity: MODERATE
Onset: DELAYED
Restlessness Incidence:
1.0-3.0%*
Severity: MILD
Onset: EARLY
Dystonic Reaction Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Dyskinesia Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Lightheadedness Incidence:
1.0-18.0%*
Severity: MILD
Onset: EARLY
Ear Pain Incidence:
1.0-4.0%*
Severity: MILD
Onset: EARLY
Causing To Be Hungry Incidence:
1.0-29.0%*
Severity: MILD
Onset: DELAYED
Shaking Incidence:
1.0-6.0%*
Severity: MILD
Onset: EARLY
Muscle Cramps Incidence:
1.0-3.0%*
Severity: MILD
Onset: DELAYED
Sore Throat Incidence:
1.0-6.0%*
Severity: MILD
Onset: DELAYED
Postural Low Blood Pressure Incidence:
>1.0%*
Severity: MODERATE
Onset: DELAYED
Stuffy Nose Incidence:
1.0-7.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
2.0-14.0%*
Severity: MILD
Onset: EARLY
Uncontrolled Urination Incidence:
2.0%*
Severity: MODERATE
Onset: EARLY
Muscle And/Or Bone Pain Incidence:
2.0-4.0%*
Severity: MILD
Onset: EARLY
Ejaculation Dysfunction Incidence:
2.0%*
Severity: MODERATE
Onset: DELAYED
Retaining Urine Incidence:
>2.0%*
Severity: MODERATE
Onset: EARLY
Vaginal Discharge Incidence:
2.0-4.0%*
Severity: MILD
Onset: DELAYED
Vaginal Infection Incidence:
2.0%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
2.0-7.0%*
Severity: MILD
Onset: EARLY
Dry Skin Incidence:
2.0%*
Severity: MILD
Onset: DELAYED
Joint Pain Incidence:
2.0-5.0%*
Severity: MILD
Onset: DELAYED
Dry Mouth Incidence:
2.0-22.0%*
Severity: MILD
Onset: EARLY
Visual Impairment Incidence:
2.0%*
Severity: SEVERE
Onset: EARLY
Low Blood Pressure Incidence:
2.0%*
Severity: MODERATE
Onset: RAPID
Weakness Incidence:
2.0-18.0%*
Severity: MILD
Onset: DELAYED
High Cholesterol Incidence:
2.8-57.6%*
Severity: MODERATE
Onset: DELAYED
Tooth Pain Incidence:
3.0-4.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
3.0%*
Severity: MODERATE
Onset: RAPID
Upset Stomach Incidence:
3.0-11.0%*
Severity: MILD
Onset: EARLY
Shortness Of Breath Incidence:
3.0%*
Severity: MODERATE
Onset: EARLY
Lazy Eye Incidence:
3.0%*
Severity: MODERATE
Onset: DELAYED
Stomach Pain Incidence:
3.0-6.0%*
Severity: MILD
Onset: EARLY
Chest Pain Incidence:
3.0%*
Severity: MODERATE
Onset: EARLY
Excessive Sweating Incidence:
3.0%*
Severity: MILD
Onset: DELAYED
Back Pain Incidence:
3.0-5.0%*
Severity: MILD
Onset: DELAYED
Restlessness Incidence:
3.0-27.0%*
Severity: MODERATE
Onset: DELAYED
Elated Mood Incidence:
3.0%*
Severity: MODERATE
Onset: EARLY
Sinus Infection Incidence:
3.0%*
Severity: MILD
Onset: DELAYED
Excessive Mucle Tone Incidence:
3.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
3.0-6.0%*
Severity: MODERATE
Onset: DELAYED
Constipation Incidence:
4.0-11.0%*
Severity: MODERATE
Onset: DELAYED
Confusion Incidence:
4.0%*
Severity: MODERATE
Onset: EARLY
Bruise Incidence:
5.0%*
Severity: MILD
Onset: DELAYED
Paresthesias Incidence:
5.0%*
Severity: MILD
Onset: DELAYED
Weight Gain Incidence:
5.0-31.0%*
Severity: MILD
Onset: DELAYED
Loss Of Memory Incidence:
5.0%*
Severity: MODERATE
Onset: DELAYED
Drowsiness Incidence:
6.0-48.0%*
Severity: MILD
Onset: EARLY
Extra Saliva Production Incidence:
6.0%*
Severity: MILD
Onset: EARLY
Rhinitis Incidence:
7.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
8.0-17.0%*
Severity: MILD
Onset: EARLY
High Triglycerides Incidence:
9.2-70.7%*
Severity: MODERATE
Onset: DELAYED
Excessive Thirst Incidence:
10.0%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
12.0%*
Severity: MILD
Onset: EARLY
Depression Incidence:
18.0%*
Severity: MODERATE
Onset: DELAYED
High Prolactin Level Incidence:
30.0-47.0%*
Severity: MODERATE
Onset: DELAYED
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Olanzapine 10mg Powder for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Olanzapine 10mg Powder for Injection(Olanzapine)
Alcohol and CNS Depressants(Olanzapine)
Avoid alcohol-containing drinks while taking this medicine. Using this drug along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how this drug affects you, and especially if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Moderate Lifestyle Interaction
Tobacco and Olanzapine 10mg Powder for Injection(Olanzapine)
Tobacco and Olanzapine(Olanzapine)
Tobacco smoke may decrease the effectiveness of Olanzapine by increasing the elimination of Olanzapine from the body. If you smoke tobacco, notify your prescriber if you experience changes in mood (like agitation or hearing or seeing things that are not really there) that may indicate that Olanzapine is not working as well for you. If you suddenly stop smoking tobacco, this may increase the actions of Olanzapine; notify your prescriber if you notice increased drowsiness, dizziness or other unusual side effects.
Moderate Lifestyle Interaction
Marijuana and Olanzapine 10mg Powder for Injection(Olanzapine)
Marijuana and Antipsychotics(Olanzapine)
Marijuana smoke may decrease the effectiveness of Antipsychotics by increasing the elimination of Antipsychotic medications from the body. If you smoke Marijuana, Medical, notify your prescriber if you experience changes in mood (like agitation or hearing or seeing things that are not really there) that may indicate your Antipsychotic medication is not working as well for you. If you suddenly stop smoking Marijuana, Medical, this may increase the actions of Antipsychotics; notify your prescriber if you notice increased drowsiness, dizziness or other unusual side effects.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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