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Olysio: Oral capsule (150mg)

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Drug Image file DrugItem_17625.JPG
Olysio 150mg Capsule
Janssen Therapeutics, Division of Janssen Products, LP
Pill Identification: TMC435 150 

What is this Medicine?

SIMEPREVIR (sim E pre vir) is an antiviral medicine. It is used with peginterferon alfa and ribavirin to treat hepatitis C. It will not work for colds, flu, or other viral infections.

In-Depth Information

Olysio 150mg Capsule

NDC: 596760225
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved





Sometimes used for but not FDA approved for the following conditions:
Hepatitis C Infection

Storage Information
Protect from light
Store in original container
Store below 86 degrees F
Olysio 150mg Capsule
Drug Image file DrugItem_17625.JPG
Janssen Therapeutics, Division of Janssen Products, LP
Pill Identification: TMC435 150 
Shape: capsule
Color: white

Reported Side Effects for Olysio 150mg Capsule

High Bilirubin Level Incidence:
<27.0%*
Severity: MODERATE
Onset: DELAYED
Photosensitivity Incidence:
5.0-7.0%*
Severity: MILD
Onset: DELAYED
Skin Rash Incidence:
11.0-28.0%*
Severity: MILD
Onset: EARLY
Itching Incidence:
11.0-22.0%*
Severity: MILD
Onset: RAPID
Shortness Of Breath Incidence:
12.0%*
Severity: MODERATE
Onset: EARLY
Inability To Sleep Incidence:
14.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
16.0%*
Severity: MILD
Onset: EARLY
Muscle Pain Incidence:
16.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
16.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
21.0%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
21.0-22.0%*
Severity: MILD
Onset: EARLY
Tired Incidence:
25.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Olysio 150mg Capsule

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Grapefruit juice and Olysio 150mg Capsule(Simeprevir)
Grapefruit juice and Simeprevir(Simeprevir)
Do not take Grapefruit Juice with Simpeprevir as this may increase the risk of side effects from simpeprevir. If your doctor decides that some intake of grapefruit juice intake is okay for your condition, you will be closely monitored. Report any new or worsening side effects, such as rash, to your health care provider.
Major Lifestyle Interaction
Alcohol and Olysio 150mg Capsule(Simeprevir)
Alcohol and Simeprevir(Simeprevir)
Do not take these drugs together without approval from your doctor. Taking these drugs together may decrease the effectiveness of your antiviral medication. If your doctor decides that taking these drugs together is right for your condition, you will be closely monitored. Immediately contact your health care provider if you feel your medicines are not working as well for you.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


Learning More About
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Patient Experiences with Olysio

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