Trazodone Information - Side Effects, Drug Interactions, Conditions
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Trazodone

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Most Commonly Used
Drug Image file DrugItem_9708.JPG
Trazodone 100mg Tab
Pliva Inc a Division of Teva USA
Pill Identification: PLIVA 434,SL 434 
Drug Image file DrugItem_9708.JPG
Trazodone 100mg Tab
Pliva Inc a Division of Teva USA
Pill Identification: PLIVA 434,SL 434 
Drug Image file DrugItem_8892.JPG
Trazodone 50mg Tab
Pliva Inc a Division of Teva USA
Pill Identification: PLIVA 433,SL 433 
Drug Image file DrugItem_8892.JPG
Trazodone 50mg Tab
Pliva Inc a Division of Teva USA
Pill Identification: PLIVA 433,SL 433 
Drug Image file DrugItem_2124.JPG
Trazodone 150mg Tab
Pliva Inc a Division of Teva USA
Pill Identification: 50 50 50,PLIVA 441  |  50 50 50,SL 441
Drug Image file DrugItem_2124.JPG
Trazodone 150mg Tab
Pliva Inc a Division of Teva USA
Pill Identification: 50 50 50,PLIVA 441  |  50 50 50,SL 441
Overview Information on Trazodone
Pharmacist Tip
Grapefruit or grapefruit juice may interfere with trazodone. Avoid consuming these products while taking this medicine.     
Trazodone is an antidepressant medicine sometimes called a "mood elevator." Your doctor may have prescribed trazodone to treat depression. It is not known exactly how trazodone works, but it is thought that it increases a chemical in the brain called serotonin. When serotonin levels are increased, it helps to regulate mood and stabilize depression.

Trazodone is the generic name for the brand-name product called Oleptro.

Trazodone is available as a tablet or an extended-release tablet. Your doctor will tell you how much trazodone to take and when to take it. Your doctor may advise you to take trazodone shortly after a meal or a light snack. It is important to take trazodone at the same time each day. Do not take more doses of trazodone than directed. Do not stop taking trazodone suddenly, except on the advice of your doctor. Stopping this medicine too quickly may cause serious side effects or your condition to worsen. Always follow your doctor's instructions.

To determine the right dose of trazodone for you, your doctor may start you on a low dose and gradually adjust it over time. It may take a couple of weeks before you start to feel the full effects of trazodone. It is important to allow enough time for trazodone to take effect. Do not stop taking trazodone without talking with your doctor first.

Before taking trazodone, talk with your doctor about any health conditions you have or have had in the past. Be sure to mention if you have had:
  • Bipolar disorder
  • Kidney or liver disease
  • Blood or bleeding disorders
  • Heart disease
  • A heart rhythm problem called long QT syndrome
  • Low blood pressure
  • Low blood sodium
  • Recent heart attack
Tell your doctor if you are pregnant, breast-feeding, or planning to become pregnant while taking trazodone.

You should not take trazodone if you have ever had a bad reaction to this medicine or are allergic to any of its ingredients. Tell your doctor about all the medicines you take, including over-the-counter medicines, herbal remedies, vitamins, and supplements. Give your doctor an up-to-date list of all your medicines so that he or she can be sure they will not interact with trazodone. If you start a new medicine, make sure to tell the doctor that you are taking trazodone.

A small number of people have become suicidal after taking trazodone. This is more common in individuals younger than age 25. It is important for you to be aware of this risk while taking trazodone. Call your doctor right away, or call 911 if an emergency, if you notice any sudden, new, or worsening depression; extreme changes in mood; or suicidal thoughts, impulses, or actions.

Trazodone can cause other serious side effects that may need emergency attention. These include:
  • Signs of an allergic reaction: itching or hives; swelling or tingling in the face, lips, mouth, throat, or hands; chest pain or tightness; or difficulty breathing or swallowing
  • Confusion, weakness, or decreased coordination
  • Stiff, rigid muscles or uncontrollable muscle twitching or tremors
  • Fever, sore throat, or other signs of infection
  • Fast, pounding, or irregular heartbeat
  • Hallucinations
  • Painful, prolonged erection
  • Extreme dizziness, light-headedness, or fainting
  • Unusual bleeding or bruising
This is not a complete list. Report any alarming systems you experience while taking trazodone to your doctor.

Less serious side effects that may happen when taking trazodone include:
  • Drowsiness or sleepiness
  • Dry mouth
  • Mild headache
  • Stomach upset, nausea, or vomiting
  • Diarrhea or constipation
  • Trouble sleeping
  • Blurred vision or trouble focusing
Talk with your doctor about these or other trazodone side effects. Let him or her know if any of these symptoms change or worsen over time.

Don't drive or operate heavy machinery until you know how trazodone affects you.

Make sure all the doctors who you see, including your dentist, know that you take trazodone. This is especially important if you need any type of surgery, because trazodone may react with anesthetic medicines used during certain procedures.


Clinical Review by Jodi Grimm, RPh and Ann Ciemnoczolowski, MS, ELS on May 15, 2013
Trazodone is an antidepressant medicine sometimes called a "mood elevator." Your doctor may have prescribed trazodone to treat depression. It is not known exactly how trazodone works, but it is thought that it increases a chemical in the brain called serotonin. When serotonin levels are increased, it helps to regulate mood and stabilize depression.

Trazodone is the generic name for the brand-name product called Oleptro.

Trazodone is available as a tablet or an extended-release tablet. Your doctor will tell you how much trazodone to take and when to take it. Your doctor may advise you to take trazodone shortly after a meal or a light snack. It is important to take trazodone at the same time each day. Do not take more doses of trazodone than directed. Do not stop taking trazodone suddenly, except on the advice of your doctor. Stopping this medicine too quickly may cause serious side effects or your condition to worsen. Always follow your doctor's instructions.

To determine the right dose of trazodone for you, your doctor may start you on a low dose and gradually adjust it over time. It may take a couple of weeks before you start to feel the full effects of trazodone. It is important to allow enough time for trazodone to take effect. Do not stop taking trazodone without talking with your doctor first.

Before taking trazodone, talk with your doctor about any health conditions you have or have had in the past. Be sure to mention if you have had:
  • Bipolar disorder
  • Kidney or liver disease
  • Blood or bleeding disorders
  • Heart disease
  • A heart rhythm problem called long QT syndrome
  • Low blood pressure
  • Low blood sodium
  • Recent heart attack
Tell your doctor if you are pregnant, breast-feeding, or planning to become pregnant while taking trazodone.

You should not take trazodone if you have ever had a bad reaction to this medicine or are allergic to any of its ingredients. Tell your doctor about all the medicines you take, including over-the-counter medicines, herbal remedies, vitamins, and supplements. Give your doctor an up-to-date list of all your medicines so that he or she can be sure they will not interact with trazodone. If you start a new medicine, make sure to tell the doctor that you are taking trazodone.

A small number of people have become suicidal after taking trazodone. This is more common in individuals younger than age 25. It is important for you to be aware of this risk while taking trazodone. Call your doctor right away, or call 911 if an emergency, if you notice any sudden, new, or worsening depression; extreme changes in mood; or suicidal thoughts, impulses, or actions.

Trazodone can cause other serious side effects that may need emergency attention. These include:
  • Signs of an allergic reaction: itching or hives; swelling or tingling in the face, lips, mouth, throat, or hands; chest pain or tightness; or difficulty breathing or swallowing
  • Confusion, weakness, or decreased coordination
  • Stiff, rigid muscles or uncontrollable muscle twitching or tremors
  • Fever, sore throat, or other signs of infection
  • Fast, pounding, or irregular heartbeat
  • Hallucinations
  • Painful, prolonged erection
  • Extreme dizziness, light-headedness, or fainting
  • Unusual bleeding or bruising
This is not a complete list. Report any alarming systems you experience while taking trazodone to your doctor.

Less serious side effects that may happen when taking trazodone include:
  • Drowsiness or sleepiness
  • Dry mouth
  • Mild headache
  • Stomach upset, nausea, or vomiting
  • Diarrhea or constipation
  • Trouble sleeping
  • Blurred vision or trouble focusing
Talk with your doctor about these or other trazodone side effects. Let him or her know if any of these symptoms change or worsen over time.

Don't drive or operate heavy machinery until you know how trazodone affects you.

Make sure all the doctors who you see, including your dentist, know that you take trazodone. This is especially important if you need any type of surgery, because trazodone may react with anesthetic medicines used during certain procedures.


Clinical Review by Jodi Grimm, RPh and Ann Ciemnoczolowski, MS, ELS on May 15, 2013

CVS Patient Statistics for Trazodone
Usage by Age
3.98%
under20_base
15.24%
20to40_base
48.94%
40to60_base
31.84%
over60_base
Most Commonly Used By CVS Patients
Usage by Gender
female_fill_graph
67.66%
female_fill_graph
male_fill_graph
32.34%
male_fill_graph
Learn More About Trazodone
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