Zyprexa Information - Side Effects, Drug Interactions, Conditions
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Zyprexa

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Most Commonly Used
Drug Image file DrugItem_5698.JPG
Zyprexa 10mg Tab
Eli Lilly and Co
Pill Identification: LILLY 4117 
Drug Image file DrugItem_5692.JPG
Zyprexa 5mg Tab
Eli Lilly and Co
Pill Identification: LILLY 4115 
Drug Image file DrugItem_5700.JPG
Zyprexa 20mg Tab
Eli Lilly and Co
Pill Identification: LILLY 4420 
Drug Image file DrugItem_5699.JPG
Zyprexa 15mg Tab
Eli Lilly and Co
Pill Identification: LILLY 4415 
Drug Image file DrugItem_5691.JPG
Zyprexa 2.5mg Tab
Eli Lilly and Co
Pill Identification: LILLY 4112 
Overview Information on Zyprexa
Pharmacist Tip
Zyprexa may make you drowsy or dizzy and can impair judgment and reaction time. While you are taking Zyprexa, it can be dangerous to drive or do other activities that require you to be alert.     
Zyprexa® is an antipsychotic medicine. Doctors prescribe Zyprexa to treat symptoms of schizophrenia and bipolar disorders. Zyprexa is approved for use in adults and in children aged 13 and older. Zyprexa should not be used to treat patients with dementia-related conditions.

Zyprexa is a brand name for the medicine olanzapine. It is available as a tablet or fast-dissolve tablet. You take Zyprexa by mouth, usually once daily. When taking the fast-dissolve tablets, Zyprexa Zydis®, make sure your hands are dry before you handle the medicine. Do not remove the tablet from the blister packet until you are ready to take it. Once you open the blister packet, put the Zyprexa Zydis fast-dissolve tablet immediately in your mouth. The tablet will quickly dissolve in your saliva so that you can easily swallow it with or without water.

Sometimes Zyprexa is used in combination with other medicines to help relieve symptoms of bipolar disorder. These medicines include lithium and valproate. Symbyax® is a combination of the medicines Zyprexa and Prozac®, and it is given to patients whose depression has been resistant to other treatments. Be sure to let your doctor know how Zyprexa is working for you, so that he or she can make adjustments to your medicines if needed.

Take Zyprexa exactly as your doctor tells you to. Taking too much or too little Zyprexa can be risky. Never take two doses of Zyprexa to make up for a missed dose. Do not stop taking Zyprexa without talking with your doctor first, even if you feel fine. Stopping Zyprexa suddenly can cause dangerous side effects.

Your doctor will want to know about all your medical conditions. Before taking Zyprexa, tell your doctor if you have or have had:
  • Heart problems
  • Liver disease
  • Diabetes
  • Prostate problems
  • Narrow-angle glaucoma
  • Bowel problems
  • Low or high blood pressure
  • High cholesterol
  • Seizures
This is not a complete list. Also, tell your doctor if you are pregnant, breast-feeding, or planning to become pregnant. If you become pregnant while taking Zyprexa, notify your doctor. Discuss any medicines you take, including over-the-counter medicines, herbal remedies, vitamins, and supplements. Some may react with Zyprexa.

Talk with your doctor about lifestyle habits, too. Your doctor may advise you not to drink alcohol while taking Zyprexa, because it can make you too drowsy. If you smoke, your doctor may need to adjust your Zyprexa dose. Zyprexa can change your body's' ability to regulate its internal temperature. Be careful not to become overheated and to always drink plenty of water. If you feel very hot, are sweating too much or not at all, have a dry mouth, feel extremely thirsty, or cannot urinate, get emergency help right away.

Like all medicines, Zyprexa may cause side effects. Some common side effects of Zyprexa include:
  • Sleepiness
  • Increased appetite or weight gain
  • Feeling tired, drowsy, or lacking energy
  • Dry mouth or increased thirst
  • Tremors or shakiness
  • Constipation
  • Dizziness
  • Restlessness
  • Changes in behavior
Teenagers who take Zyprexa may be more prone to side effects such a headache, abdominal pain, pain in the arms and legs, and tiredness. Tell your doctor about these or any other side effects you notice while taking Zyprexa, especially if they become worse, worry you, or will not go away.

More serious Zyprexa side effects may require immediate care. Watch for:
  • Signs of an allergic reaction: itching and hives; swelling of the face, mouth, or throat; trouble breathing or swallowing; or chest pain
  • High fever, increased sweating, rigid muscles, confusion, and changes in breathing, heartbeat, or blood pressure
  • Uncontrollable muscle movements or twitching
  • Seizures
  • Numbness or weakness in an arm or leg or on one side of the body
  • Suicidal thoughts or impulses, or any self-destructive or troubling thoughts or behaviors
If you notice these or any other alarming symptoms while taking Zyprexa, report them to a health care provider immediately or call 911 if an emergency.


Clinical Review by Jodi Grimm, RPh and Ann Ciemnoczolowski, MS, ELS on May 15, 2013
Zyprexa® is an antipsychotic medicine. Doctors prescribe Zyprexa to treat symptoms of schizophrenia and bipolar disorders. Zyprexa is approved for use in adults and in children aged 13 and older. Zyprexa should not be used to treat patients with dementia-related conditions.

Zyprexa is a brand name for the medicine olanzapine. It is available as a tablet or fast-dissolve tablet. You take Zyprexa by mouth, usually once daily. When taking the fast-dissolve tablets, Zyprexa Zydis®, make sure your hands are dry before you handle the medicine. Do not remove the tablet from the blister packet until you are ready to take it. Once you open the blister packet, put the Zyprexa Zydis fast-dissolve tablet immediately in your mouth. The tablet will quickly dissolve in your saliva so that you can easily swallow it with or without water.

Sometimes Zyprexa is used in combination with other medicines to help relieve symptoms of bipolar disorder. These medicines include lithium and valproate. Symbyax® is a combination of the medicines Zyprexa and Prozac®, and it is given to patients whose depression has been resistant to other treatments. Be sure to let your doctor know how Zyprexa is working for you, so that he or she can make adjustments to your medicines if needed.

Take Zyprexa exactly as your doctor tells you to. Taking too much or too little Zyprexa can be risky. Never take two doses of Zyprexa to make up for a missed dose. Do not stop taking Zyprexa without talking with your doctor first, even if you feel fine. Stopping Zyprexa suddenly can cause dangerous side effects.

Your doctor will want to know about all your medical conditions. Before taking Zyprexa, tell your doctor if you have or have had:
  • Heart problems
  • Liver disease
  • Diabetes
  • Prostate problems
  • Narrow-angle glaucoma
  • Bowel problems
  • Low or high blood pressure
  • High cholesterol
  • Seizures
This is not a complete list. Also, tell your doctor if you are pregnant, breast-feeding, or planning to become pregnant. If you become pregnant while taking Zyprexa, notify your doctor. Discuss any medicines you take, including over-the-counter medicines, herbal remedies, vitamins, and supplements. Some may react with Zyprexa.

Talk with your doctor about lifestyle habits, too. Your doctor may advise you not to drink alcohol while taking Zyprexa, because it can make you too drowsy. If you smoke, your doctor may need to adjust your Zyprexa dose. Zyprexa can change your body's' ability to regulate its internal temperature. Be careful not to become overheated and to always drink plenty of water. If you feel very hot, are sweating too much or not at all, have a dry mouth, feel extremely thirsty, or cannot urinate, get emergency help right away.

Like all medicines, Zyprexa may cause side effects. Some common side effects of Zyprexa include:
  • Sleepiness
  • Increased appetite or weight gain
  • Feeling tired, drowsy, or lacking energy
  • Dry mouth or increased thirst
  • Tremors or shakiness
  • Constipation
  • Dizziness
  • Restlessness
  • Changes in behavior
Teenagers who take Zyprexa may be more prone to side effects such a headache, abdominal pain, pain in the arms and legs, and tiredness. Tell your doctor about these or any other side effects you notice while taking Zyprexa, especially if they become worse, worry you, or will not go away.

More serious Zyprexa side effects may require immediate care. Watch for:
  • Signs of an allergic reaction: itching and hives; swelling of the face, mouth, or throat; trouble breathing or swallowing; or chest pain
  • High fever, increased sweating, rigid muscles, confusion, and changes in breathing, heartbeat, or blood pressure
  • Uncontrollable muscle movements or twitching
  • Seizures
  • Numbness or weakness in an arm or leg or on one side of the body
  • Suicidal thoughts or impulses, or any self-destructive or troubling thoughts or behaviors
If you notice these or any other alarming symptoms while taking Zyprexa, report them to a health care provider immediately or call 911 if an emergency.


Clinical Review by Jodi Grimm, RPh and Ann Ciemnoczolowski, MS, ELS on May 15, 2013

CVS Patient Statistics for Zyprexa
Usage by Age
10.44%
under20_base
29.42%
20to40_base
41.61%
40to60_base
18.52%
over60_base
Most Commonly Used By CVS Patients
Usage by Gender
female_fill_graph
43.98%
female_fill_graph
male_fill_graph
56.02%
male_fill_graph
Learn More About Zyprexa
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Patient Experiences with Zyprexa

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