Oxycodone, Ibuprofen Oral Tablet 5-400Mg Drug Medication Dosage Information
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Oxycodone, Ibuprofen: Oral tablet (5-400mg)

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Drug Image file DrugItem_16704.JPG
Oxycodone/Ibu 5mg-400mg Tab
Actavis Inc. Elizabeth LLC
Pill Identification: LOGO 29 
Drug Image file DrugItem_7298.JPG
Combunox 5mg-400mg Tab
Actavis- US Brands formerly Forest Pharmaceuticals Inc
Pill Identification: F P  |  5400

What is this Medicine?

IBUPROFEN; OXYCODONE (eye BYOO proe fen; ox i KOE done) is a pain reliever. It is used to treat moderate to severe pain for 7 days or less.

Similar Brand Name Drugs : Combunox: Oral tablet (5-400mg)
In-Depth Information
Select a Medication

Oxycodone Hydrochloride/Ibuprofen 5mg-400mg Tablet

NDC: 002284029
  • Prescription Required
  • Federally Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Severe Pain, Moderate Pain

Sometimes used for but not FDA approved for the following conditions:
Bone Pain, Migraine, Myalgia, Arthralgia, Dental Pain, Headache

Storage Information
Store at 77 degrees F; excursions permitted to 59-86 degrees F
Oxycodone Hydrochloride/Ibuprofen 5mg-400mg Tablet
Drug Image file DrugItem_16704.JPG
Actavis Inc. Elizabeth LLC
Pill Identification: LOGO 29 
Shape: oblong
Color: yellow

Reported Side Effects for Oxycodone Hydrochloride/Ibuprofen 5mg-400mg Tablet

Fluid Retention Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Elated Mood Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Belching Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Elevated Hepatic Enzymes Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Bruise Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Metallic Taste Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Chills Incidence:
<2.0%*
Severity: MILD
Onset: RAPID
Chest Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Back Pain Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Weakness Incidence:
<3.3%*
Severity: MILD
Onset: DELAYED
Fainting Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Infection Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Skin Rash Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Irritated Blood Vessels Incidence:
<2.0%*
Severity: MODERATE
Onset: RAPID
Peripheral Vasodilation Incidence:
<3.0%*
Severity: MODERATE
Onset: RAPID
Increased Urination Incidence:
<2.0%*
Severity: MILD
Onset: EARLY
Hypoxia Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Excessive Mucle Tone Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Hyperkinesis Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Inability To Sleep Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Bowel Obstruction Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Low Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Low Potassium Levels Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Swelling Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
<2.1%*
Severity: MILD
Onset: EARLY
Nervousness Incidence:
<2.0%*
Severity: MILD
Onset: DELAYED
Anemia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Lazy Eye Incidence:
<2.0%*
Severity: MODERATE
Onset: DELAYED
Stomach Pain Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Retaining Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Blood In The Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Sore Throat Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Gas Incidence:
1.0%*
Severity: MILD
Onset: EARLY
Itching Incidence:
>1.0%*
Severity: MILD
Onset: RAPID
Diaphoresis Incidence:
1.6%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
2.1%*
Severity: MILD
Onset: EARLY
Fever Incidence:
3.0%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
>4.5%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
4.5-5.3%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
5.1-19.2%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
7.3-17.4%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
8.8-25.4%*
Severity: MILD
Onset: EARLY
Addiction Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Addiction Incidence:
>10.0%*
Severity: MODERATE
Onset: DELAYED
Headache Incidence:
10.2%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Oxycodone Hydrochloride/Ibuprofen 5mg-400mg Tablet

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Oxycodone Hydrochloride/Ibuprofen 5mg-400mg Tablet(Ibuprofen)
Alcohol and Nonsteroidal antiinflammatory drugs (systemic)(Ibuprofen)
Side effects from this drug may get worse if you drink alcohol-containing drinks. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. It is best to limit or avoid alcohol containing drinks while taking this drug, even with short term use. Many non-prescription products for headaches, pain, arthritis, or sinus pain contain drugs that may cause stomach problems along with alcohol; closely read labels before taking any medicines with alcohol-containing drinks.
Major Lifestyle Interaction
Alcohol and Oxycodone Hydrochloride/Ibuprofen 5mg-400mg Tablet(Oxycodone Hydrochloride)
Alcohol and CNS Depressants(Oxycodone Hydrochloride)
Avoid alcohol-containing drinks while taking this medicine. Using this drug along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how this drug affects you, and especially if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Major Lifestyle Interaction
Grapefruit juice and Oxycodone Hydrochloride/Ibuprofen 5mg-400mg Tablet(Oxycodone Hydrochloride)
Grapefruit juice and Oxycodone(Oxycodone Hydrochloride)
Side effects from oxycodone may get worse if you eat or drink grapefruit juice. Talk to your doctor first. Contact your doctor right away if you have slurred speech, confusion, weakness, or trouble breathing. Do not drive or operate machinery until you know how this affects you.
Moderate Lifestyle Interaction
Tobacco and Oxycodone Hydrochloride/Ibuprofen 5mg-400mg Tablet(Ibuprofen)
Tobacco and Nonsteroidal antiinflammatory drugs (systemic)(Ibuprofen)
Side effects from Nonsteroidal anti-inflammatory drugs may get worse if you use tobacco-containing products such as cigarettes. If you have persistent stomach upset, vomit blood or what looks like coffee grounds, or have black, tarry stools, contact your health care provider immediately. Many non-prescription products contain NSAIDs; closely read labels before taking any medicines. Eye or Skin products containing NSAIDs should not interact with tobacco.
Moderate Lifestyle Interaction
Marijuana and Oxycodone Hydrochloride/Ibuprofen 5mg-400mg Tablet(Ibuprofen)
Marijuana and Nonsteroidal antiinflammatory drugs (systemic)(Ibuprofen)
Although an interaction is possible, these drugs may be used together. In therory, the actions of Marijuana, Medical may be decreased if you take Nonsteroidal Antiinflammatory Drugs (NSAIDs). However, the importance of this interaction is not known. Patients receiving this drug combination may notice decreased euphoria and heart rate.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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