Pentam Lyophilisate For Solution For Injection 300Mg Drug Medication Dosage Information
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Pentam: Lyophilisate for solution for injection (300mg)

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What is this Medicine?

PENTAMIDINE (pen TAM i deen) is an anti-infective drug. It is used to treat Pneumocystis carinii pneumonia (PCP).

In-Depth Information

Pentam 300mg Powder for Injection

NDC: 633230113
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Pneumocystis Pneumonia (PCP)

Sometimes used for but not FDA approved for the following conditions:
Leishmaniasis, Trypanosomiasis, Trypanosomiasis Prophylaxis

Storage Information
Store at room temperature (between 59 to 86 degrees F)
Protect from light
Pentam 300mg Powder for Injection

Reported Side Effects for Pentam 300mg Powder for Injection

Enlarged Liver Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Coughing Up Blood Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Deafness Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hallucinations Incidence:
<1.7%*
Severity: MODERATE
Onset: EARLY
Back Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Skin Redness Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Eosinophilia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Emotional Lability Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Lightheadedness Incidence:
<45.1%*
Severity: MILD
Onset: EARLY
Cyanosis Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Conjunctivitis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Chills Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Breathing Difficulties Incidence:
<15.0%*
Severity: SEVERE
Onset: RAPID
Blurred Vision Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Vomiting Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Inflamed Blood Vessels Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Fainting Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Brain Attack Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Convulsions Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Collapsed Lung Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Nerve Pain Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Fluid Retention Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Pancreas Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Infection Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Increased Blood Sugar Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Decreased Memory Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Eosinophilic Pneumonia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Night Sweats Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Tissue Death Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Rapid Breathing Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Removal Of Spleen Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Skin Ulcer Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Rhinitis Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Kidney Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Prolonged Bleeding Time Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Irritated Blood Vessels Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Peripheral Vasodilation Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Stomach Ulcer Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Paresthesias Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Paranoia Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Pancytopenia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Mouth Sores Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Melena Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Tiredness Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Vocal Cord Spasm Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Inflamed Vocal Cords Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Injection Site Reaction Incidence:
<11.1%*
Severity: MILD
Onset: RAPID
Hypoesthesia Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Overbreathing Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Brain Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Inability To Sleep Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Low Blood Pressure Incidence:
<5.0%*
Severity: MODERATE
Onset: RAPID
Low Magnesium Levels Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low Blood Sugar Incidence:
<5.9%*
Severity: MODERATE
Onset: EARLY
Low Calcium Levels Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Extra Saliva Production Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
High Potassium Level Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Headache Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Gout Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Gum Inflammation Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Inflamed Stomach Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Fever Incidence:
<51.0%*
Severity: MILD
Onset: EARLY
Throat Inflammation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Shortness Of Breath Incidence:
<48.3%*
Severity: MODERATE
Onset: EARLY
Upset Stomach Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Drowsiness Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Loose Stools Incidence:
<5.0%*
Severity: MILD
Onset: EARLY
Diabetic Ketoacidosis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Diabetes Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Depression Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Constipation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Colon Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Yeast Infection Incidence:
<5.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Eyes Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Joint Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Nervousness Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Angioedema Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Blood In The Urine Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Stomach Pain Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Dry Mouth Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Dry Skin Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Balance Problems Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Rapid Heart Rate Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Uncontrolled Urination Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Shaking Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Torsade De Pointes Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Low Platelet Count Incidence:
<2.6%*
Severity: MODERATE
Onset: DELAYED
Stevens-Johnson Syndrome Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Muscle Pain Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
SIADH Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Itching Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Stuffy Nose Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Lung Inflammation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Sore Throat Incidence:
<5.0%*
Severity: MILD
Onset: DELAYED
Low White Blood Cells Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Eye Pain Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Anemia Incidence:
1.0-5.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
1.0-5.9%*
Severity: MILD
Onset: EARLY
Wheezing Incidence:
1.0-32.4%*
Severity: MODERATE
Onset: RAPID
Flu Incidence:
1.0-5.0%*
Severity: MILD
Onset: DELAYED
Chest Pain Incidence:
1.0-5.0%*
Severity: MODERATE
Onset: EARLY
Sinus Infection Incidence:
1.0-5.0%*
Severity: MILD
Onset: DELAYED
Metallic Taste Incidence:
1.7%*
Severity: MILD
Onset: EARLY
Confusion Incidence:
1.7%*
Severity: MODERATE
Onset: EARLY
Skin Rash Incidence:
3.3%*
Severity: MILD
Onset: EARLY
Decreased Appetite Incidence:
5.9%*
Severity: MILD
Onset: DELAYED
Low Kidney Function Incidence:
8.5%*
Severity: SEVERE
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
8.7%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
10.4%*
Severity: MODERATE
Onset: DELAYED
Cough Incidence:
38.0-62.7%*
Severity: MILD
Onset: DELAYED
Tired Incidence:
65.7%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Avoid - This drug is known to cause harm to infants when taken by nursing mothers.


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