Pentoxifylline Oral Tablet, Extended Release 400Mg Drug Medication Dosage Information
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Pentoxifylline: Oral tablet, extended release (400mg)

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Drug Image file DrugItem_7069.JPG
Pentoxifylline 400mg ER Tab
Mylan Pharmaceuticals Inc
Pill Identification: MYLAN  |  357
Drug Image file DrugItem_2487.JPG
Pentoxifylline 400mg ER Tab
Teva Pharmaceuticals USA Inc
Pill Identification: BVF  |  0117
Drug Image file DrugItem_1991.JPG
Pentoxifylline 400mg ER Tab
Apotex Corp
Pill Identification: APO 033 

What is this Medicine?

PENTOXIFYLLINE (pen tox I fi leen) improves blood flow. This medicine helps to decrease the pain, discomfort, or cramps you can get from having poor circulation in your legs.

CVS Pharmacy Patient Statistics for Pentoxifylline: Oral tablet, extended release(400mg)
Generic vs. Brand Name Usage*
*Brand contains same active ingredient but may not represent FDA-approved generic equivalent
Usage By Strength
In-Depth Information
Select a Medication

Pentoxifylline 400mg Extended-Release Tablet

NDC: 003780357
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Claudication

Sometimes used for but not FDA approved for the following conditions:
Behcet's Syndrome, Kawasaki Disease, Sickle Cell Disease, Diabetic Neuropathy

Storage Information
Protect from light
Store at controlled room temperature (between 68 and 77 degrees F)
Pentoxifylline 400mg Extended-Release Tablet
Drug Image file DrugItem_7069.JPG
Mylan Pharmaceuticals Inc
Pill Identification: MYLAN  |  357
Shape: oblong
Color: purple

Reported Side Effects for Pentoxifylline 400mg Extended-Release Tablet

Liver Infection Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Flu Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Yellow Skin Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cell Counts Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Convulsions Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Abnormal Heart Rhythm Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Inflamed Brain Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Blurred Vision Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Confusion Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Conjunctivitis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Elevated Hepatic Enzymes Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Inflamed Vocal Cords Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Feeling Sick Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Pancytopenia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Bruises Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Skin Rash Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Scotomata Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Rapid Heart Rate Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Weight Gain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Weight Loss Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Severe Allergy Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Angioedema Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Decreased Appetite Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Nervousness Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Aplastic Anemia Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Cholecystitis Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Constipation Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Depression Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Shortness Of Breath Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Swelling Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Nose Bleed Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Extra Saliva Production Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Low Blood Pressure Incidence:
<1.0%*
Severity: MODERATE
Onset: RAPID
Stuffy Nose Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Itching Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Low Platelet Count Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Dry Mouth Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Cholestasis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Chest Pain Incidence:
0.3%*
Severity: MODERATE
Onset: EARLY
Chest Pain Incidence:
0.3%*
Severity: MODERATE
Onset: EARLY
Gas Incidence:
0.6%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
1.2%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
2.2%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


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