Phenergan Solution For Injection 25Mg Drug Medication Dosage Information
show timeout overlay link

Your Session Is About to Expire

This online session is about to expire due to inactivity. Click Continue to return to page.

  • myWeekly Ad

Phenergan: Solution for injection (25mg)

Also see:
  • Get answers to Frequently Asked Questions (FAQs)
  • Find other class related drugs
  • Find additional patient usage statistics

Visit Drug Summary Page
Drug Image file default-drug-image.png


What is this Medicine?

PROMETHAZINE (proe METH a zeen) is an antihistamine. It is used to treat allergic reactions and to treat or prevent nausea and vomiting from illness or motion sickness. It is also used to make you sleep before surgery, and to help treat pain or nausea after surgery.

In-Depth Information
Select a Medication

Phenergan 25mg/ml Solution for Injection

NDC: 006416082
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Pruritus, Nausea/vomiting, Post-operative Nausea/vomiting (PONV), Post-operative Nausea/vomiting (PONV) Prophylaxis, Sedation Induction

Sometimes used for but not FDA approved for the following conditions:
Hyperemesis Gravidarum, Pregnancy-induced Nausea/vomiting

Storage Information
Protect from light
Discard product if it contains particulate matter, is cloudy, or discolored
Store in carton until time of use
Store at controlled room temperature (between 68 and 77 degrees F)
Phenergan 25mg/ml Solution for Injection

Reported Side Effects for Phenergan 25mg/ml Solution for Injection

Dystonic Reaction Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Pseudoparkinsonism Incidence:
1.0%*
Severity: MODERATE
Onset: DELAYED
Inability To Sleep Incidence:
3.2%*
Severity: MILD
Onset: EARLY
Shortness Of Breath Incidence:
3.2%*
Severity: MODERATE
Onset: EARLY
Confusion Incidence:
3.2%*
Severity: MODERATE
Onset: EARLY
Restlessness Incidence:
4.0-14.0%*
Severity: MODERATE
Onset: DELAYED
Dry Mouth Incidence:
9.7%*
Severity: MILD
Onset: EARLY
Excitability Incidence:
9.7%*
Severity: MODERATE
Onset: EARLY
Injection Site Reaction Incidence:
21.0%*
Severity: MILD
Onset: RAPID
Drowsiness Incidence:
38.0-71.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Phenergan 25mg/ml Solution for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Phenergan 25mg/ml Solution for Injection(Promethazine Hydrochloride)
Alcohol and CNS Depressants(Promethazine Hydrochloride)
Avoid alcohol-containing drinks while taking this medicine. Using this drug along with alcohol can lead to serious side effects. You may feel drowsy or more tired when taking these drugs together. Do not drive or operate machinery until you know how this drug affects you, and especially if you are drinking alcohol-containing beverages. If you notice slurred speech, confusion, severe weakness, or difficulty breathing, contact your health care provider immediately.
Moderate Lifestyle Interaction
Tobacco and Phenergan 25mg/ml Solution for Injection(Promethazine Hydrochloride)
Tobacco and Phenothiazines(Promethazine Hydrochloride)
Tobacco smoking may reduce the effectiveness of this drug in treating your condition; Tobacco smoke contains substances that speed the removal of this drug from the body. Alternatively, if you take this drug and suddenly stop Tobacco smoking, you may feel more drowsy or tired, or may experience confusion, dizziness, difficulty in movement or other side effects. If you will stop smoking, use care in driving or operating machinery until you know how this drug will affect you. Make sure your prescriber is aware that you smoke Tobacco or if you plan to stop smoking. Report any unusual side effects promptly.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


Learning More About
Visit the Drug Summary page where you can:
  • Get answers to Frequently Asked Questions (FAQs)
  • Find other class related drugs
  • Find additional patient usage statistics
Learn More
Patient Experiences with Phenergan

Be the first to share your experience!

We want to help our customers stay educated about the medications they are taking. Submit your own observations and experiences to benefit others.

Average Scores
Easy to Take 
0 / 5
0 / 5
Works as Intended 
0 / 5
0 / 5
Tolerable 
0 / 5
0 / 5