Piperacillin, Tazobactam Powder For Solution For Injection 2.25G Drug Medication Dosage Information
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Piperacillin, Tazobactam: Powder for solution for injection (2.25g)

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What is this Medicine?

PIPERACILLIN; TAZOBACTAM (pi PER a sil in; ta zoe BAK tam) is a penicillin antibiotic. It is used to treat certain kinds of bacterial infections. It will not work for colds, flu, or other viral infections.

In-Depth Information
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Piperacillin/Tazobactam 2.25g Powder for Injection

NDC: 551500119
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Peritonitis, Pneumonia, Intraabdominal Infections, Intraabdominal Abscess, Nosocomial Pneumonia, Diabetic Foot Ulcer, Pelvic Inflammatory Disease (PID), Cellulitis, Skin And Skin Structure Infections, Endometritis, Appendicitis, Lower Respiratory Tract Infections, Community-acquired Pneumonia

Sometimes used for but not FDA approved for the following conditions:
Bacteremia, Febrile Neutropenia, Pyelonephritis, Cystic Fibrosis, Septicemia, Urinary Tract Infection (UTI), Surgical Infection Prophylaxis

Storage Information
Store between 68 to 77 degrees F, excursions permitted 59 to 86 degrees F
Reconstituted product is stable for up to 24 hours at room temperature and 48 hours under refrigeration
Piperacillin/Tazobactam 2.25g Powder for Injection

Reported Side Effects for Piperacillin/Tazobactam 2.25g Powder for Injection

Anaphylactoid Reactions Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Elevated Hepatic Enzymes Incidence:
<1.4%*
Severity: MODERATE
Onset: DELAYED
Eosinophilia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Flushing Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Injection Site Reaction Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Irritated Blood Vessels Incidence:
<1.3%*
Severity: MODERATE
Onset: RAPID
Bruises Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Kidney Failure Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Severe Allergy Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Anemia Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Joint Pain Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Nose Bleed Incidence:
<1.0%*
Severity: MILD
Onset: DELAYED
Low Blood Sugar Incidence:
<1.0%*
Severity: MODERATE
Onset: EARLY
Low Potassium Levels Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low Blood Pressure Incidence:
<1.3%*
Severity: MODERATE
Onset: RAPID
Low Platelet Count Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Mouth Ulcers Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Pseudomembranous Colitis Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Muscle Pain Incidence:
<1.0%*
Severity: MILD
Onset: EARLY
Stomach Pain Incidence:
1.3-1.8%*
Severity: MILD
Onset: EARLY
High Platelet Count Incidence:
1.4%*
Severity: MODERATE
Onset: DELAYED
Yeast Infection Incidence:
1.6-3.9%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
1.9-3.3%*
Severity: MILD
Onset: EARLY
Fever Incidence:
2.4-3.2%*
Severity: MILD
Onset: EARLY
Vomiting Incidence:
2.7-3.3%*
Severity: MILD
Onset: EARLY
Itching Incidence:
3.1-3.2%*
Severity: MILD
Onset: RAPID
Blistery Rash Incidence:
3.9-4.2%*
Severity: MODERATE
Onset: EARLY
Rash With Pustules Incidence:
3.9-4.2%*
Severity: MILD
Onset: EARLY
Hives Incidence:
3.9-4.2%*
Severity: MILD
Onset: RAPID
Skin Rash Incidence:
3.9-4.2%*
Severity: MILD
Onset: EARLY
Inability To Sleep Incidence:
4.5-6.6%*
Severity: MILD
Onset: EARLY
Headache Incidence:
4.5-7.7%*
Severity: MILD
Onset: EARLY
Upset Stomach Incidence:
5.8-6.9%*
Severity: MILD
Onset: EARLY
Constipation Incidence:
7.7-8.4%*
Severity: MODERATE
Onset: DELAYED
Loose Stools Incidence:
11.3-20.0%*
Severity: MILD
Onset: EARLY
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Pregnancy & Lactation Information
FIRST Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

SECOND Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

THIRD Trimester

Class B - Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate and well-controlled studies in pregnant women. OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Lactation

Compatible - This drug is generally safe to take by nursing mothers.


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