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PLEGRIDY: Solution for injection (125mcg)

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What is this Medicine?

PEGINTERFERON BETA-1a (peg in ter FEER on BAY ta) helps to decrease the number of multiple sclerosis attacks and to slow disability in people with relapsing forms of the disease. This medicine does not cure multiple sclerosis.

In-Depth Information
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Plegridy Pen 125mcg/0.5ml Auto-Injector Solution for Injection

NDC: 644060011
  • Prescription Required
  • Not a Controlled Drug
    (CSA Schedule)
  • FDA Approved




FDA approved for the following conditions:
Multiple Sclerosis

Storage Information
Refrigerated product should reach room temperature before administration
Refrigerate (between 36 and 46 degrees F)
Protect from light
Store in carton until time of use
Do not freeze
May be stored between 36 to 77 degrees F, away from heat and light, for up to 30 days if refrigeration is not available
Discard if product has been frozen
Plegridy Pen 125mcg/0.5ml Auto-Injector Solution for Injection

Reported Side Effects for Plegridy Pen 125mcg/0.5ml Auto-Injector Solution for Injection

Tissue Death Incidence:
<1.0%*
Severity: SEVERE
Onset: EARLY
Convulsions Incidence:
<1.0%*
Severity: SEVERE
Onset: DELAYED
Hives Incidence:
<1.0%*
Severity: MILD
Onset: RAPID
Low Platelet Count Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Low White Blood Cells Incidence:
<1.0%*
Severity: MODERATE
Onset: DELAYED
Angioedema Incidence:
<1.0%*
Severity: SEVERE
Onset: RAPID
Elevated Hepatic Enzymes Incidence:
3.0-6.0%*
Severity: MODERATE
Onset: DELAYED
Itching Incidence:
4.0%*
Severity: MILD
Onset: RAPID
High Body Temperature Incidence:
4.0%*
Severity: MODERATE
Onset: DELAYED
Vomiting Incidence:
5.0%*
Severity: MILD
Onset: EARLY
Low White Blood Cell Counts Incidence:
7.0%*
Severity: MODERATE
Onset: DELAYED
Upset Stomach Incidence:
9.0%*
Severity: MILD
Onset: EARLY
Joint Pain Incidence:
11.0%*
Severity: MILD
Onset: DELAYED
Weakness Incidence:
13.0%*
Severity: MILD
Onset: DELAYED
Chills Incidence:
17.0%*
Severity: MILD
Onset: RAPID
Muscle Pain Incidence:
19.0%*
Severity: MILD
Onset: EARLY
Headache Incidence:
44.0%*
Severity: MILD
Onset: EARLY
Fever Incidence:
45.0%*
Severity: MILD
Onset: EARLY
Injection Site Reaction Incidence:
66.0%*
Severity: MILD
Onset: RAPID
*This is an approximate aggregated range of reported side effects from clinical studies performed on this drug. Your experience with this drug may be different.
Daily Life Interactions for Plegridy Pen 125mcg/0.5ml Auto-Injector Solution for Injection

Elements of your daily lifestyle may have an effect on the medications you are taking. Drug interactions can result in unwanted side effects, reduce the effectiveness of your medicine or possibly increase the action of a particular medicine.

Major Lifestyle Interaction
Alcohol and Plegridy Pen 125mcg/0.5ml Auto-Injector Solution for Injection(Peginterferon Beta-1a)
Alcohol and Peginterferon Beta-1a(Peginterferon Beta-1a)
Side effects from Peginterferon Beta-1a, such as liver damage, may be more likely if you take Ethanol. Avoid taking alcoholic beverages during treatment with Peginterferon Beta-1a.
Pregnancy & Lactation Information
FIRST Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

SECOND Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

THIRD Trimester

Class C - Animal studies have shown an adverse effect and there are no adequate and well-controlled studies in pregnant women. OR No animal studies have been conducted and there are no adequate and well-controlled studies in pregnant women.

Lactation

Caution - Not enough information is available to rule out harm to infants when this drug is taken by nursing mothers.


Learning More About
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Patient Experiences with PLEGRIDY

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